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Organometallic-Nanoparticle Constructs as CO-Release Theranostics: An Evaluation with Some Group 7 and 8 Metals

Year: 2026
Type: article
Abstract: A central issue with the use of transition metal carbonyl complexes in CO-release medical therapy centers around the attendant side effects associated with the products after CO release (iCORMs). In this study, we examined the feasibility of an organometallic-nanoparticle (AuNP@OM) construct as a means to stabilize the iCORM of a photoactivable CO-releasing molecule (photoCORM), as well as for tracking. Four metal carbonyl complexes comprising a group 7 or 8 metal and bearing the 3-di(pyridin-2-yl)benzo[g]quinoxaline (dpb) ligand were assessed, along with their AuNP@OM constructs, for such use.
DOI: 10.1021/acsabm.6c01529
Authors: Teresa Yu Ping Lim, Zhen Xuan Wong, Benedict Jin Kiat Bay, Darryl Heng Yik Ooi, Christophe Sandt, Ricky Yu-Syun Fan, Yongxin Li, Kien Voon Kong, Helene C. Bertrand, Weng Kee Leong
Institutions: Centre National de la Recherche Scientifique, Nanyang Technological University, Université Paris Sciences et Lettres, École Normale Supérieure - PSL, Sorbonne Université, Agency for Science, Technology and Research, Synchrotron SOLEIL, National Taiwan University
Language: English
Open Access status: hybrid
Estimated APC paid: $4,500
OpenAlex ID: W7225830126
FWCI:
Cites: 68
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