Work

Metabolism of amino-acids

Year: 1935
Type: article
Abstract: Oxidation of 1 ( + )-glutamic acid without formation of ammonia.THE starting-point of this investigation was the observation that glutamic acid behaves differently from all the other ax-amino-acids in guinea-pig and rabbit kidneys, in that, although it increases the oxygen uptake even more than any other amino-acid of the i-series, in most cases it actually diminishes ammonia formation.In guinea-pig kidney, the oxygen uptake is increased about 100-150% (Table I) whilst in most experiments no ammonia at all is detectable in the presence of 1( + )-glutamic acid [Krebs, 1933, 2]1.
Language: English
Subfield: Biochemistry
Open Access status: bronze
OpenAlex ID: W73242948
FWCI: 2.457
Cites: 3
Cited by: 587
Related to: 10