Year: 2007
Type: article
Abstract: does not directly cause the observed immunological effects of social disruption.Taken together, these data indicate that social disruption stress caused an increase in anxietylike behaviors, but not depressive-like behaviors.This increase in anxiety-like behavior was also observed in aged mice, which were predisposed toward increased inflammation, and this effect was further exacerbated by social defeat.Pharmacologic blockade of anxiety-like behavior neither attenuated nor exacerbated the previously-observed defeatinduced changes to immune function, suggesting that the SDR-induced anxiety-like state does not causally affect immunity.v Dedicated to my family and the many friends who supported me throughout my education.vi
Author: Steven G. Kinsey
Institution: The Ohio State University
Language: English
Subfield: Behavioral Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W74547413