Circadian rhythmicity of human plasma cortisol and PHA-induced lymphocyte transformation.
Year: 1975
Type: article
Abstract: In two experiments, lymphocytes from six healthy subjects were sampled every 4 hr, counted, and cultured with PHA. Plasma cortisol in the same blood samples was measured and showed an expected circadian variation in level. A circadian rhythm in lymphocyte transformability to PHA was found to coincide directly with the cortisol level but varied inversely with lymphocyte numbers. The relationship between cortisol and lymphocyte transformability could be fortuitous or might indicate a role for cortisol in controlling lymphocyte function in vivo.
Source: PubMed Central
Authors: H B Tavadia, K A Fleming, P D Hume, H W Simpson
Language: English
Subfield: Behavioral Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W75611809