Fungus infections of the urinary tract.
Year: 1958
Type: article
Study design: Observational Study
Abstract: Although bacterial infections of the urinary tract have received considerable attention in recent years, diseases of this system due to fungi have only been sporadically mentioned in the literature. The majority of cases reported have been instances of renal involvement secondary to dissemination of the fungi by the circulation. Only a few instances of primary diseases have been noted. With the increase in number of fungal infections observed in recent years, " it would be expected that a similar rise might occur in the incidence of primary urinary tract infections due to fungi. Since the clinical appearance of fungal and bacterial infections of the kidney and bladder are often indistinguishable, the diagnosis must be made from information obtained by urine culture. Fungi frequently appear in the urine in small numbers and are usually discarded as contaminants by laboratory personnel. However, with the use of quantitative methods of culture, it is possible to distinguish a significant bacteriuria (or "funguria"). ' This report describes observations made on 15 patients whose urines contained large numbers of fungi. MATERIALS AND METHODS Urine specimens were obtained in male and female patients by "clean voided" technique. Previous observations have demonstrated that this is a satisfactory method of collection when quantitative bacteriological procedures are employed.28 8 Urine was diluted serially in nutrient broth and 1 ml. of a 1: 100 dilution incorporated into an agar pour plate. (Earlier in the work an additional plate was made with an aliquot of a 1: 10,000 dilution.) Additional samples of undiluted urine were inoculated into blood and desoxycholate agar plates and thioglycollate broth. Cultures were examined after incubation for 48 hours at 37 ° C. In this manner an estimate of the type and quantity of organisms was obtained and further identification performed by appropriate methods.
Source: PubMed Central
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W86162677