Work

Analysis of Subgroup Effects in Randomized Trials When Subgroup Membership Is Informatively Missing: Application to the Madit Ii Study

Year: 2008

Type: article

Abstract: In this paper, we develop and implement a general sensitivity analysis methodology for drawing inference about subgroup effects in a two-arm randomized trial when subgroup status is only known for a non-random sample in one of the trial arms. The methodology is developed in the context of the MADIT II study, a randomized trial designed to evaluate the effectiveness of implantable defibrillators on survival.

Source: Collection of Biostatistics Research Archive

Authors: Daniel O. Scharfstein, Georgiana Onicescu, Steven N. Goodman

Institution: Johns Hopkins University

Language: English

Topic: Statistical Methods in Clinical Trials

Subfield: Statistics and Probability

Field: Mathematics

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W903976544

FWCI:

Cites: 11

Cited by:

Related to: 10