Thermodynamic, Kinetic, and Dynamics Studies of the Allosteric Ligand-Responsive Regulatory Protein TRAP
Year: 2011
Type: article
Abstract: Life is made possible by an astounding array of interactions between highly-evolved biomolecules that serve a variety of specific functions.Their functions are dictated by structure and flexibility or "dynamics," both of which can change upon interaction with a partner molecule.Understanding these changes To Mark, you are a model scientist because of your intelligence, critical nature, patience, and generosity.You are a model mentor because you care to learn who I am, you encourage me to be genuine, you cultivate an individualized environment for optimal learning, and you remind me to see the bigger picture.Even still, you are so much more than your impressive and inspiring career, and I will continue to learn more from you, despite the distance.To my committee members Chris Jaroniec, Thomas Magliery, Richard Swenson, and Zhengrong Wu, for your thoughtful feedback and genuine interest in my academic health.To my family, for your unconditional support and love, and for making sure I didn't drift too far off course.To Ma, for your eager ears, for enlightening me to the wonders of the human mind, and for reminding me to graduate.To Dad, for your inspiring intellect, leadership, and patience, for reminding me how to appear more human, and for teaching me how to build a fence.To Melissa, Joe, Joey, Jack, and Liam, for closing the distance via phone and email, and for believing in me as a role model.To Matt and Yolanda, for your selflessness and generosity, and for many happy memories of frequent visits.To Alli, Chad, Nick, Julie, Carly and Aidan, for making sure I still know how to have fun like a child.v To my friends Ross and Eli, for helping to make science so much fun.To Amber, for your strength of mind and body, your resilience, and your irreplaceable affection.Our similarities bind us together, while our differences intrigue me to draw ever closer and learn more.You're such a good girlfriend!vi
Author: Ian R. Kleckner
Institution: The Ohio State University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Funder: National Institutes of Health
OpenAlex ID: W93512439