The Influence of Urethane Narcosis Upon the Specific Dynamic Action of Glycocoll and Glucose in Rabbits
Year: 1927
Type: article
Abstract: These investigations were made in order to determine the effect of narcosis upon the so called specific dynamic action of foodstuffs.No attempt will be made to review the literature on the subject of specific dynamic action; only such works will be referred to as have a definite bearing upon the problem under study.So far as we have been able to learn, no direct studies have been made on the relationship of narcosis to specific dynamic action.Chance isolated observations have been found in four sources.Aub (1) refers to unpublished work performed by himself and two associates in which they found the effects of thyroid and adrenalin on metabolism were present under urethane anesthesia, even when the stimulation from caffeine and amino acids had disappeared.Weiss and Klein (2) note the rise in the metabolism of rabbits urethanized with 1 gm. of urethane per kilo after the feeding of 10 gm. of glucose.In a paper in the Pawlow Memorial Volume, by Krogh and Rehberg (3), the authors record a single experiment performed on a rabbit narcotized with 1.9 gm. per kilo of urethane in which 4 gm. of glucose were given intragastrically without any rise in the metabolism.Reiss and Weiss (4) record an experiment in which 10 gm. of sugar were given intravenously to a rabbit narcotized with 2.5 gm. of urethane per kilo in which they observed no increase in metabolism.
Source: Journal of Biological Chemistry
Authors: M.S. Guttmacher, Robert Weiss
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W960819183