Work

The Sialic Acids

Year: 1966

Type: article

Abstract: A novel type of sugar nucleotide, containing 1 rather than 2 phosphate residues, was isolated from Escherichia coli K-235. The nucleotide was shown to be cytidine 5'-monophospho-N-acetylneuraminic acid in which the sialic acid was glycosidically linked to the phosphate residue. The glycoside was highly sensitive to acid, and optical rotation studies showed that it was the β anomer, in contrast to other known, natural, sialidase-sensitive sialic acid glycosides.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(18)96391-x

Authors: Donald G. Comb, Donald R. Watson, Saul Roseman

Institution: University of Michigan

Language: English

Topic: Glycosylation and Glycoproteins Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W982669008

FWCI: 0.475

Cites: 19

Cited by: 48

Related to: 10