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Laurence Danober

Pathophysiological mechanisms of genetic absence epilepsy in the rat
1998 · L Danober, C Deransart, et al. · Progress in Neurobiology · 584
The amygdala is critical for seizure propagation from brainstem to forebrain
1997 · E Hirsch, L Danober, et al. · Neuroscience · 92
C-fos expression after single and kindled audiogenic seizures in Wistar rats
1994 · Simone Simler, Edouard Hirsch, et al. · Neuroscience Letters · 76
Design, Synthesis, and Pharmacology of Novel 7-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of AMPA Receptors
2007 · Pierre Francotte, Pascal de Tullio, et al. · Journal of Medicinal Chemistry · 73
Electrophysiological studies on the hippocampus and prefrontal cortex assessing the effects of amyloidosis in amyloid precursor protein 23 transgenic mice
2003 · S Roder, L Danober, et al. · Neuroscience · 72
New Fluorinated 1,2,4-Benzothiadiazine 1,1-Dioxides: Discovery of an Orally Active Cognitive Enhancer Acting through Potentiation of the 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors
2010 · Pierre Francotte, Eric Goffin, et al. · Journal of Medicinal Chemistry · 60
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GABAA receptor impairment in the genetic absence epilepsy rats from Strasbourg (GAERS): an immunocytochemical and receptor binding autoradiographic study
1993 · R Spreafico, T Mennini, et al. · Epilepsy Research · 58
Effects of cholinergic drugs on genetic absence seizures in rats
1993 · Laurence Danober, Antoine Depaulis, et al. · European Journal of Pharmacology · 49
Thalamic NMDA transmission in a genetic model of absence epilepsy in rats
1996 · C. Koerner, L. Danober, et al. · Epilepsy Research · 46
Synthesis, Pharmacological and Structural Characterization, and Thermodynamic Aspects of GluA2-Positive Allosteric Modulators with a 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxide Scaffold
2013 · Ann-Beth Nørholm, Pierre Francotte, et al. · Journal of Medicinal Chemistry · 42
Mechanisms and functional significance of a slow inhibitory potential in neurons of the lateral amygdala
1998 · Laurence Danober, Hans‐Christian Pape · European Journal of Neuroscience · 40
Strychnine-sensitive glycine responses in neurons of the lateral amygdala: an electrophysiological and immunocytochemical characterization
1998 · L Danober, H.-C Pape · Neuroscience · 39
Quantitative assessment of oligomeric amyloid β peptide binding to α7 nicotinic receptor
2019 · Erika Cecon, Julie Dam, et al. · British Journal of Pharmacology · 38
DRUG FOCUS: S 18986: A Positive Allosteric Modulator of AMPA‐Type Glutamate Receptors Pharmacological Profile of a Novel Cognitive Enhancer
2010 · Katy Bernard, Laurence Danober, et al. · CNS Neuroscience & Therapeutics · 37
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Mesopontine cholinergic control over generalized non-convulsive seizures in a genetic model of absence epilepsy in the rat
1995 · L. Danober, A. Depaulis, et al. · Neuroscience · 34
Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure–Activity Relationship at AMPA Receptors
2016 · Anja Probst Larsen, Pierre Francotte, et al. · ACS Chemical Neuroscience · 31
Synthesis and pharmacological evaluation of a second generation of pyridothiadiazine 1,1-dioxides acting as AMPA potentiators
2008 · Pierre Francotte, Pascal de Tullio, et al. · Bioorganic & Medicinal Chemistry · 31
Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors
2017 · Sylvie Bretin, Caroline Louis, et al. · PLoS ONE · 28
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Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2 H -1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2 H -1,2,4-benzothiadiazine 1,1-Dioxides
2014 · Pierre Francotte, Ann-Beth Nørholm, et al. · Journal of Medicinal Chemistry · 27
Ring-Fused Thiadiazines as Core Structures for the Development of Potent AMPA Receptor Potentiators
2010 · B. Pirotte, P. Francotte, et al. · Current Medicinal Chemistry · 23
Nucleus basalis lesions suppress spike and wave discharges in rats with spontaneous absence-epilepsy
1994 · L. Danober, M. Vergnes, et al. · Neuroscience · 23
Development of Thiophenic Analogues of Benzothiadiazine Dioxides as New Powerful Potentiators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid (AMPA) Receptors
2013 · Pierre Francotte, Eric Goffin, et al. · Journal of Medicinal Chemistry · 22
Development of Thiochroman Dioxide Analogues of Benzothiadiazine Dioxides as New Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors
2021 · Koffi Sénam Etsè, Jerzy Dorosz, et al. · ACS Chemical Neuroscience · 20
Thermodynamic Characterization of New Positive Allosteric Modulators Binding to the Glutamate Receptor A2 Ligand-Binding Domain: Combining Experimental and Computational Methods Unravels Differences in Driving Forces
2014 · Ann-Beth Nørholm, Pierre Francotte, et al. · Journal of Chemical Information and Modeling · 18
In vivo pharmacological profile of S 38093, a novel histamine H3 receptor inverse agonist
2017 · Fany Panayi, Aurore Sors, et al. · European Journal of Pharmacology · 16
Works count: 70
Citation count: 1,653
H-index: 22
I10-index: 29
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