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Philip E. Ryan

Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line.
2002 · Clifford G Tepper, David L Boucher, et al. · PubMed · 263
Cbl and Human Myeloid Neoplasms: The Cbl Oncogene Comes of Age
2010 · Stephen C. Kales, Philip E. Ryan, et al. · Cancer Research · 130
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Regulating the regulator: negative regulation of Cbl ubiquitin ligases
2006 · Philip E. Ryan, Gareth C. Davies, et al. · Trends in Biochemical Sciences · 93
The N Terminus of Cbl-c Regulates Ubiquitin Ligase Activity by Modulating Affinity for the Ubiquitin-conjugating Enzyme
2010 · Philip E. Ryan, Nina Sivadasan-Nair, et al. · Journal of Biological Chemistry · 37
Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells
2005 · Clifford G. Tepper, Jeffrey P. Gregg, et al. · The Prostate · 35
EGFRvIII undergoes activation-dependent downregulation mediated by the Cbl proteins
2006 · G C Davies, P E Ryan, et al. · Oncogene · 34
Cbl interacts with multiple E2s in vitro and in cells
2019 · Mariya S. Liyasova, Ke Ma, et al. · PLoS ONE · 25
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Cbl-c Ubiquitin Ligase Activity Is Increased via the Interaction of Its RING Finger Domain with a LIM Domain of the Paxillin Homolog, Hic 5
2012 · Philip E. Ryan, Stephen C. Kales, et al. · PLoS ONE · 20
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Cbl exposes its RING finger
2012 · Stephen C Kales, Philip E Ryan, et al. · Nature Structural & Molecular Biology · 20
T Cells in G1 Provide a Memory-Like Response to Secondary Stimulation
2005 · Ivana Munitic, Philip E Ryan, et al. · The Journal of Immunology · 20
Loss of function Cbl-c mutations in solid tumors
2019 · Silvano Rakeem Daniels, Mariya Liyasova, et al. · PLoS ONE · 17
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The translational science training program at NIH: Introducing early career researchers to the science and operation of translation of basic research to medical interventions
2016 · C. Taylor Gilliland, G. Sitta Sittampalam, et al. · Biochemistry and Molecular Biology Education · 14
Abstract 4542: Ube2d family members, Ube2e family members and Ube2w modulate the ubiquitination and degradation of EGFR by Cbl
2016 · Ke Ma, Philip Ryan, et al. · Cancer Research · 3
Abstract 555: Loss of function Cbl-c mutations in solid tumors
2018 · Silvano R. Daniels, Stephen C. Kales, et al. · Cancer Research
Abstract 4965: Multiple ubiquitin-conjugating enzymes modulate the ubiquitination and downregulation of the EGFR by the Cbl RING finger ubiquitin ligase
2015 · Ke Ma, Philip Ryan, et al. · Cancer Research
Abstract 4429: Loss of function Cbl-c mutations in solid tumors
2014 · Stephen C. Kales, Philip E. Ryan, et al. · Cancer Research
Abstract 543: A loss of function Cbl-c mutation in a murine breast cancer model.
2013 · Stephen C. Kales, Philip E. Ryan, et al. · Cancer Research
Characterization of the ubiquitin ligase Cbl-c
2008 · Ryan, Philip · ProQuest Demo Repository
The constitutively active EGFR vIII and hyperactive L858R EGFR mutants do not escape Cbl mediated ubiquitination and degradation
2005 · Gareth Davies, Phillip E. Ryan, et al. · Cancer Research
Works count: 19
Citation count: 711
H-index: 12
I10-index: 12
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