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Yhun Yhong Sheen

Observed names: Y SHEEN, Y Y Sheen, Y. Y. Sheen, Y. Yhong Sheen, Y.Y. Sheen, YHUN YHONG SHEEN, Yhun Sheen, Yhun Y Sheen, Yhun Y. SHEEN, Yhun Y. Sheen, Yhun-Yhong Sheen
Observed institutions: National Institutes of Health, Ewha Womans University, University of Illinois Urbana-Champaign, University of Illinois System, University of Illinois Chicago, Eunice Kennedy Shriver National Institute of Child Health and Human Development
ORCID: 0000-0002-4928-1611
Observed ORCID: 0000-0002-4928-1611
OpenAlex ID: A5000413124
A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.
1992 · J.K. Ritter, F Chen, et al. · Journal of Biological Chemistry · 470
The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles
2009 · Minjung Cho, Wan-Seob Cho, et al. · Toxicology Letters · 305
IN-1130, a novel transforming growth factor-β type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy
2006 · J.-A. Moon, H.-T. Kim, et al. · Kidney International · 197
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Discovery of N -((4-([1,2,4]Triazolo[1,5- a ]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1 H -imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A Highly Potent, Selective, and Orally Bioavailable Inhibitor of TGF-β Type I Receptor Kinase as Cancer Immunotherapeutic/Antifibrotic Agent
2014 · Cheng Hua Jin, Maddeboina Krishnaiah, et al. · Journal of Medicinal Chemistry · 169
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EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling
2014 · Sang-A Park, Min-Jin Kim, et al. · Cellular and Molecular Life Sciences · 154
Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells. 3,4-catechol estrogens and estriol as primary substrates.
1990 · J K Ritter, Y Y Sheen, et al. · Journal of Biological Chemistry · 152
EW-7197, a Novel ALK-5 Kinase Inhibitor, Potently Inhibits Breast to Lung Metastasis
2014 · Ji Yeon Son, So-Yeon Park, et al. · Molecular Cancer Therapeutics · 115
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Antiestrogen action in breast cancer cells: Modulation of proliferation and protein synthesis, and interaction with estrogen receptors and additional antiestrogen binding sites
1985 · Benita S. Katzenellenbogen, Margaret Ann Miller, et al. · Breast Cancer Research and Treatment · 111
Targeting the Transforming Growth Factor-β Signaling in Cancer Therapy
2013 · Yhun Yhong Sheen, Min-Jin Kim, et al. · Biomolecules & Therapeutics · 105
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Two human liver cDNAs encode UDP-glucuronosyltransferases with 2 log differences in activity toward parallel substrates including hyodeoxycholic acid and certain estrogen derivatives
1992 · Joseph K. Ritter, Fan Chen, et al. · Biochemistry · 97
High aldehyde dehydrogenase activity enhances stem cell features in breast cancer cells by activating hypoxia-inducible factor-2α
2012 · Ran-Ju Kim, Jeong-Ran Park, et al. · Cancer Letters · 90
Peroxisome Proliferator-Activated Receptor-γ Activator 15-Deoxy-Δ12,14-Prostaglandin J2 Inhibits Neuroblastoma Cell Growth through Induction of Apoptosis: Association with Extracellular Signal-Regulated Kinase Signal Pathway
2003 · Eun Joung Kim, Ki Sook Park, et al. · Journal of Pharmacology and Experimental Therapeutics · 73
Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells
2015 · So-Yeon Park, Min-Jin Kim, et al. · Oncotarget · 70
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Aberrant expressions of pathogenic phenotype in Alzheimer's diseased transgenic mice carrying NSE-controlled APPsw
2004 · Dae Y. Hwang, Jung S. Cho, et al. · Experimental Neurology · 69
TIMP-1 mediates TGF-β-dependent crosstalk between hepatic stellate and cancer cells via FAK signaling
2015 · Sang-A Park, Min-Jin Kim, et al. · Scientific Reports · 68
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An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial–mesenchymal transition
2014 · Chul-Yong Park, Kyung Nan Min, et al. · Cancer Letters · 56
TGF-β Type I Receptor Kinase Inhibitor EW-7197 Suppresses Cholestatic Liver Fibrosis by Inhibiting HIF1α-Induced Epithelial Mesenchymal Transition
2016 · Min-Jin Kim, Sang-A Park, et al. · Cellular Physiology and Biochemistry · 53
Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: cDNA cloning, sequence, and expression in Saccharomyces cerevisiae
1991 · Joseph K. Ritter, Ida S. Owens, et al. · Biochemistry · 50
Antiestrogen Stimulation of the Production of a 37,000 Molecular Weight Secreted Protein and Estrogen Stimulation of the Production of a 32,000 Molecular Weight Secreted Protein in MCF-7 Human Breast Cancer Cells*
1987 · YHUN YHONG SHEEN, BENITA S. KATZENELLENBOGEN · Endocrinology · 45
EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung
2011 · Chul-Yong Park, Jee-Yeon Son, et al. · European Journal of Cancer · 44
An Evaluation of the Role of Antiestrogen-Binding Sites in Mediating the Growth Modulatory Effects of Antiestrogens: Studies Usingt-Butylphenoxyethyl Diethylamine, a Compound Lacking Affinity for the Estrogen Receptor*
1985 · YHUN YHONG SHEEN, DAVID M. SIMPSON, et al. · Endocrinology · 39
Synthesis and biological evaluation of 1-substituted-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors
2011 · Cheng Hua Jin, Maddeboina Krishnaiah, et al. · Bioorganic & Medicinal Chemistry Letters · 38
Inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-stimulated Cyp1a1 promoter activity by hypoxic agents
2000 · Ji-E Kim, Yhun Y Sheen · Biochemical Pharmacology · 38
4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazole and -pyrazole derivatives as potent and selective inhibitors of transforming growth factor-β type I receptor kinase
2014 · Cheng Hua Jin, Maddeboina Krishnaiah, et al. · Bioorganic & Medicinal Chemistry · 36
Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors
2011 · Cheng Hua Jin, Domalapally Sreenu, et al. · European Journal of Medicinal Chemistry · 36
Works count: 147
Citation count: 3,293
H-index: 29
I10-index: 50
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