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Umut Şahin

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
2004 · Umut Sahin, Gisela Weskamp, et al. · The Journal of Cell Biology · 1,013
Sumoylation on its 25th anniversary: mechanisms, pathology, and emerging concepts
2020 · Arda B. Celen, Umut Sahin · FEBS Journal · 252
Oxidative stress–induced assembly of PML nuclear bodies controls sumoylation of partner proteins
2014 · Umut Sahin, Omar Ferhi, et al. · The Journal of Cell Biology · 237
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Essential Role for ADAM19 in Cardiovascular Morphogenesis
2003 · Hong-Ming Zhou, Gisela Weskamp, et al. · Molecular and Cellular Biology · 139
Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells
2015 · Hiba El Hajj, Zeina Dassouki, et al. · Blood · 129
Ectodomain shedding of the EGF‐receptor ligand epigen is mediated by ADAM17
2006 · Umut Sahin, Carl P. Blobel · FEBS Letters · 123
Sumoylation in Physiology, Pathology and Therapy
2022 · Umut Sahin, Hugues de Thé, et al. · Cells · 98
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PML nuclear bodies: Assembly and oxidative stress-sensitive sumoylation
2014 · Umut Sahin, Hugues de Thé, et al. · Nucleus · 98
ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation
2014 · Zeina Dassouki, Umut Sahin, et al. · Blood · 84
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PML nuclear bodies: regulation, function and therapeutic perspectives
2014 · Umut Sahin, Valérie Lallemand‐Breitenbach, et al. · The Journal of Pathology · 66
Interferon controls SUMO availability via the Lin28 and let-7 axis to impede virus replication
2014 · Umut Sahin, Omar Ferhi, et al. · Nature Communications · 61
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A Sensitive Method to Monitor Ectodomain Shedding of Ligands of the Epidermal Growth Factor Receptor
2006 · Umut Sahin, Gisela Weskamp, et al. · Humana Press eBooks · 52
Sumoylation of Human Argonaute 2 at Lysine-402 Regulates Its Stability
2014 · Umut Sahin, Pierre Lapaquette, et al. · PLoS ONE · 38
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Characterization of the catalytic properties of the membrane-anchored metalloproteinase ADAM9 in cell-based assays
2017 · Thorsten Maretzky, Steven Swendeman, et al. · Biochemical Journal · 23
Detection of Protein SUMOylation In Situ by Proximity Ligation Assays
2016 · Umut Sahin, Florence Jollivet, et al. · Methods in molecular biology · 16
Sumoylation of Cas9 at lysine 848 regulates protein stability and DNA binding
2022 · Tunahan Ergünay, Özgecan Ayhan, et al. · Life Science Alliance · 15
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A molecule inducing androgen receptor degradation and selectively targeting prostate cancer cells
2019 · Serge Auvin, Harun Öztürk, et al. · Life Science Alliance · 14
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A novel homozygous loss-of-function variant in SOD1 causing progressive spastic tetraplegia and axial hypotonia
2023 · Arman Çakar, Emre Pekbilir, et al. · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · 11
Human immunodeficiency virus type 1 impairs sumoylation
2022 · Bilgül Mete, Emre Pekbilir, et al. · Life Science Alliance · 9
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Pml loss worsens NEK1 ‐linked ALS and Pml induction drives NEK1 degradation, precluding disease onset
2026 · Panagiota Georgiadou, Bahriye Erkaya, et al. · FEBS Journal · 3
Cas9 beyond CRISPR – SUMOylation , effector‐like potential and pathogenic adaptation
2025 · Umut Sahin · FEBS Journal · 1
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Tax as a therapeutic target in ATL
2015 · Zeina Dassouki, Umut Sahin, et al. · Retrovirology · 1
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The centrosome-cilium-centriolar satellite axis in neurodegenerative diseases
2026 · Umut Sahin, Elif Nur Firat-Karalar · EMBO Reports
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Author response for "Pml loss worsens NEK1-linked ALS and Pml induction drives NEK1 degradation, precluding disease onset"
2026 · Panagiota Georgiadou, Bahriye Erkaya, et al. · Publons reviews and discussion
Umut Şahin: SUMOylation in health and disease
2022 · Umut Şahin · Life Science Alliance
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Works count: 28
Citation count: 2,483
H-index: 15
I10-index: 18
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