Author

Christoph Loenarz

Observed names: C. Loenarz, Christoph Lönarz, Loenarz Christoph, Loenarz, Christoph

Institution: University of Freiburg

Observed institutions: University of Freiburg, University of Oxford

ORCID: 0000-0002-8843-2531

Observed ORCID: 0000-0002-8843-2531

OpenAlex ID: A5000825987

Expanding chemical biology of 2-oxoglutarate oxygenases

2008 · Christoph Loenarz, Christopher J Schofield · Nature Chemical Biology · 498

Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study

2008 · Nicola A. Burgess-Brown, Sujata Sharma, et al. · Protein Expression and Purification · 339

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

2008 · Patrick J. Pollard, Christoph Loenarz, et al. · Biochemical Journal · 296

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Structural studies on human 2-oxoglutarate dependent oxygenases

2010 · Michael A McDonough, Christoph Loenarz, et al. · Current Opinion in Structural Biology · 280

Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases

2010 · Christoph Loenarz, Christopher J. Schofield · Trends in Biochemical Sciences · 274

Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases

2009 · Rasheduzzaman Chowdhury, Michael A. McDonough, et al. · Structure · 241

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The hypoxia‐inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens

2010 · Christoph Loenarz, Mathew L Coleman, et al. · EMBO Reports · 235

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Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family

2011 · Lars Hillringhaus, Wyatt W. Yue, et al. · Journal of Biological Chemistry · 175

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PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase

2009 · Christoph Loenarz, Wei Ge, et al. · Human Molecular Genetics · 171

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

2012 · Wei Ge, Alexander Wolf, et al. · Nature Chemical Biology · 154

Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)

2011 · Armin Thalhammer, Zuzana Bencokova, et al. · PLoS ONE · 151

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Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy

2014 · Christoph Loenarz, Rok Sekirnik, et al. · Proceedings of the National Academy of Sciences · 127

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OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

2014 · Rachelle S. Singleton, Phebee Liu-Yi, et al. · Proceedings of the National Academy of Sciences · 122

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Kinetic Rationale for Selectivity toward N- and C-terminal Oxygen-dependent Degradation Domain Substrates Mediated by a Loop Region of Hypoxia-Inducible Factor Prolyl Hydroxylases

2007 · Emily Flashman, Eleanor A.L. Bagg, et al. · Journal of Biological Chemistry · 87

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Oxygenase Catalyzed 5-Methylcytosine Hydroxylation

2009 · Christoph Loenarz, Christopher J. Schofield · Chemistry & Biology · 85

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A mechanism for induction of a hypoxic response by vaccinia virus

2013 · Michela Mazzon, Nicholas E. Peters, et al. · Proceedings of the National Academy of Sciences · 83

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Evidence for a Stereoelectronic Effect in Human Oxygen Sensing

2009 · Christoph Loenarz, Jasmin Mecinović, et al. · Angewandte Chemie International Edition · 68

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates

2010 · Armin Thalhammer, Jasmin Mecinović, et al. · Organic & Biomolecular Chemistry · 60

Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth

2014 · Maximiliano J. Katz, Julieta M. Acevedo, et al. · Proceedings of the National Academy of Sciences · 50

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Identification and Characterization of a Novel Evolutionarily Conserved Lysine-specific Methyltransferase Targeting Eukaryotic Translation Elongation Factor 2 (eEF2)

2014 · Erna Davydova, Angela Y.Y. Ho, et al. · Journal of Biological Chemistry · 48

Application of a Proteolysis/Mass Spectrometry Method for Investigating the Effects of Inhibitors on Hydroxylase Structure

2009 · Christopher J. Stubbs, Christoph Loenarz, et al. · Journal of Medicinal Chemistry · 46

Biomimetic S ‐Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes**

2023 · Lukas Gericke, Dipali Mhaindarkar, et al. · ChemBioChem · 40

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Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases

2015 · Shoichiro Horita, John S. Scotti, et al. · Structure · 39

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Crystal structure of the PHF8 Jumonji domain, an Nε‐methyl lysine demethylase

2010 · Wyatt W. Yue, Viktorija Hozjan, et al. · FEBS Letters · 37

A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C α ‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase

2022 · Jana Gagsteiger, Sören Jahn, et al. · Angewandte Chemie International Edition · 29

Works count: 55

Citation count: 3,963

H-index: 26

I10-index: 36