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Edward Avezov

Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
2013 · J. Nangalia, C.E. Massie, et al. · New England Journal of Medicine · 1,755
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An Optical Technique for Mapping Microviscosity Dynamics in Cellular Organelles
2018 · Joseph E. Chambers, Markéta Kubánková, et al. · ACS Nano · 182
Endoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5–6GlcNAc2 in Glycoprotein ER-associated Degradation
2007 · Edward Avezov, Zehavit Frenkel, et al. · Molecular Biology of the Cell · 141
Intracellular Sources of ROS/H2O2 in Health and Neurodegeneration: Spotlight on Endoplasmic Reticulum
2021 · Tasuku Konno, Eduardo Pinho Melo, et al. · Cells · 140
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Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox
2013 · Edward Avezov, Benedict C.S. Cross, et al. · The Journal of Cell Biology · 106
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The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes
2020 · Meng Lu, Francesca W. van Tartwijk, et al. · Science Advances · 101
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Single particle trajectories reveal active endoplasmic reticulum luminal flow
2018 · David Holcman, Pierre Parutto, et al. · Nature Cell Biology · 95
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models
2023 · Aamir S. Mukadam, Lauren V. C. Miller, et al. · Science · 83
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ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity
2017 · Ilir Mehmeti, Stephan Lortz, et al. · Free Radical Biology and Medicine · 83
Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm
2014 · Pawan Gulati, Edward Avezov, et al. · Bioscience Reports · 82
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Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker
2015 · Steffen Preissler, Joseph E Chambers, et al. · eLife · 77
PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress
2007 · Maria Kondratyev, Edward Avezov, et al. · Experimental Cell Research · 76
Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants
2014 · Satoshi Tsunoda, Edward Avezov, et al. · eLife · 72
ERO1-independent production of H2O2 within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding
2015 · Tasuku Konno, Eduardo Pinho Melo, et al. · The Journal of Cell Biology · 67
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PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress
2024 · Karinder K. Brar, Daniel T. Hughes, et al. · Science · 64
A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation
2016 · K Kollmann, W Warsch, et al. · Leukemia · 62
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A Shared Endoplasmic Reticulum-associated Degradation Pathway Involving the EDEM1 Protein for Glycosylated and Nonglycosylated Proteins
2012 · Marina Shenkman, Bella Groisman, et al. · Journal of Biological Chemistry · 55
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Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum
2015 · Edward Avezov, Tasuku Konno, et al. · BMC Biology · 48
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TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2
2017 · Eduardo Pinho Melo, Carlos Lopes, et al. · BMC Biology · 45
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ERnet: a tool for the semantic segmentation and quantitative analysis of endoplasmic reticulum topology
2023 · Meng Lu, Charles N. Christensen, et al. · Nature Methods · 44
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Z-α 1 -antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state
2022 · Joseph E. Chambers, Nikita Zubkov, et al. · Science Advances · 44
Stress-induced protein disaggregation in the endoplasmic reticulum catalysed by BiP
2022 · Eduardo Pinho Melo, Tasuku Konno, et al. · Nature Communications · 43
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THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer
2022 · Arnaud Blomme, Coralie Peter, et al. · EMBO Molecular Medicine · 36
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Intracellular Aβ42 Aggregation Leads to Cellular Thermogenesis
2022 · Chyi Wei Chung, Amberley D. Stephens, et al. · Journal of the American Chemical Society · 33
Mannosidase IA is in Quality Control Vesicles and Participates in Glycoprotein Targeting to ERAD
2016 · Navit Ogen-Shtern, Edward Avezov, et al. · Journal of Molecular Biology · 30
Works count: 75
Citation count: 3,729
H-index: 26
I10-index: 32
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