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Author

Mohammad Roghanian

Observed names: M. Roghanian, Roghanian, Mohammad
Observed institutions: University of Copenhagen, Lund University, Hvidovre Hospital, Copenhagen University Hospital, Rigshospitalet, Umeå Centre for Microbial Research, Newcastle University, Umeå University
ORCID: 0000-0003-3116-3817
Observed ORCID: 0000-0003-3116-3817
OpenAlex ID: A5002016887
RETRACTED: Stochastic induction of persister cells by HipA through (p)ppGpp-mediated activation of mRNA endonucleases
2015 · Elsa Germain, Mohammad Roghanian, et al. · Proceedings of the National Academy of Sciences · 162
Stepwise mechanism for transcription fidelity
2010 · Yulia Yuzenkova, Aleksandra Bochkareva, et al. · BMC Biology · 105
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Activation of the Stringent Response by Loading of RelA-tRNA Complexes at the Ribosomal A-Site
2018 · Kristoffer Skovbo Winther, Mohammad Roghanian, et al. · Molecular Cell · 99
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Bacterial global regulators DksA/ppGpp increase fidelity of transcription
2015 · Mohammad Roghanian, Nikolay Zenkin, et al. · Nucleic Acids Research · 57
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Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre
2011 · M. Roghanian, Y. Yuzenkova, et al. · Nucleic Acids Research · 54
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RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis
2021 · Tatsuaki Kurata, Tetiana Brodiazhenko, et al. · Molecular Cell · 49
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(p)ppGpp-mediated stress response induced by defects in outer membrane biogenesis and ATP production promotes survival in Escherichia coli
2019 · Mohammad Roghanian, Szabolcs Semsey, et al. · Scientific Reports · 48
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The C-Terminal RRM/ACT Domain Is Crucial for Fine-Tuning the Activation of ‘Long’ RelA-SpoT Homolog Enzymes by Ribosomal Complexes
2020 · Hiraku Takada, Mohammad Roghanian, et al. · Frontiers in Microbiology · 47
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(p)ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains
2021 · Mohammad Roghanian, Katleen Van Nerom, et al. · Molecular Cell · 45
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Photorhabdus antibacterial Rhs polymorphic toxin inhibits translation through ADP-ribosylation of 23S ribosomal RNA
2021 · Dukas Jurėnas, Amaury Payelleville, et al. · Nucleic Acids Research · 45
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Ribosome association primes the stringent factor Rel for tRNA-dependent locking in the A-site and activation of (p)ppGpp synthesis
2020 · Hiraku Takada, Mohammad Roghanian, et al. · Nucleic Acids Research · 41
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Fatty acid starvation activates RelA by depleting lysine precursor pyruvate
2019 · Anurag Kumar Sinha, Kristoffer Skovbo Winther, et al. · Molecular Microbiology · 39
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Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase
2019 · Stine Vang Nielsen, Kathryn Jane Turnbull, et al. · mBio · 38
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Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA
2019 · Kathryn Jane Turnbull, Ievgen Dzhygyr, et al. · Frontiers in Microbiology · 33
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Tagetitoxin inhibits transcription by stabilizing pre-translocated state of the elongation complex
2013 · Y. Yuzenkova, M. Roghanian, et al. · Nucleic Acids Research · 32
Structure of SpoT reveals evolutionary tuning of catalysis via conformational constraint
2022 · Hedvig Tamman, Karin Ernits, et al. · Nature Chemical Biology · 28
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Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Module-Encoded mRNases
2016 · Chengzhe Tian, Mohammad Roghanian, et al. · Journal of Bacteriology · 25
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(p)ppGpp imposes graded transcriptional changes to impair motility and promote antibiotic tolerance in biofilms
2025 · Florian Engelhardt, Kathryn Turnbull, et al. · npj Biofilms and Microbiomes · 23
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Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes
2022 · Timm O Koller, Kathryn J Turnbull, et al. · Nucleic Acids Research · 22
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Alarmone (p)ppGpp regulates the transition from pathogenicity to mutualism in P hotorhabdus luminescens
2016 · Ragnhild Bager, Mohammad Roghanian, et al. · Molecular Microbiology · 14
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Multiple active centers of multi-subunit RNA polymerases
2012 · Yulia Yuzenkova, Mohammad Roghanian, et al. · Transcription · 11
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Nonhydrolysable Analogues of (p)ppGpp and (p)ppApp Alarmone Nucleotides as Novel Molecular Tools
2021 · Viktor Mojr, Mohammad Roghanian, et al. · ACS Chemical Biology · 4
Pathogen virulence does not alter antibiotic efficacy under growth-matched in vivo conditions
2026 · Victor Wolff Bengtsen, Susanne Häussler, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
Nanobody-mediated control of long RSH Rel and RelA catalysis by restriction of their conformational landscape
2026 · Katleen Van Nerom, Andres Ainelo, et al. · Nature Communications · 1
Role of O-specific antigen expression in Pseudomonas aeruginosa pathogenicity
2026 · Oliver Hartmann, Matthias Preusse, et al. · mBio
Works count: 32
Citation count: 1,023
H-index: 19
I10-index: 21
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