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Michel L. Belley

The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs
2000 · Mark Abramovitz, Mohammed Adam, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 557
Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist
1989 · T. R. Jones, R. Zamboni, et al. · Canadian Journal of Physiology and Pharmacology · 270
Pharmacology of montelukast sodium (Singulair™), a potent and selective leukotriene D4receptor antagonist
1995 · T. R. Jones, M. Labelle, et al. · Canadian Journal of Physiology and Pharmacology · 250
γ-Aminobutyric Acid Type B Receptors with Specific Heterodimer Composition and Postsynaptic Actions in Hippocampal Neurons Are Targets of Anticonvulsant Gabapentin Action
2001 · Gordon Y.K. Ng, Sandrine Bertrand, et al. · Molecular Pharmacology · 146
An efficient synthesis of LTD4 antagonist L-699,392
1993 · A. O. King, E. G. Corley, et al. · The Journal of Organic Chemistry · 137
From indomethacin to a selective COX-2 inhibitor: Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors
1996 · W.C. Black, C. Bayly, et al. · Bioorganic & Medicinal Chemistry Letters · 109
Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme induction
1995 · M. Labelle, M. Belley, et al. · Bioorganic & Medicinal Chemistry Letters · 100
Comparison of the Antinociceptive Profiles of Gabapentin and 3-Methylgabapentin in Rat Models of Acute and Persistent Pain: Implications for Mechanism of Action
2005 · M.O. Urban, K. Ren, et al. · Journal of Pharmacology and Experimental Therapeutics · 73
The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14
2011 · Jacques Yves Gauthier, Michel Belley, et al. · Bioorganic & Medicinal Chemistry Letters · 61
Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor
2008 · Yongxin Han, Michel Belley, et al. · Bioorganic & Medicinal Chemistry Letters · 57
.alpha.-(Arylsulfonamido)borneols as auxiliaries in asymmetric synthesis: an efficient and highly stereoselective method for the reduction of .alpha.-keto esters
1993 · Yi Bin Xiang, Ken Snow, et al. · The Journal of Organic Chemistry · 57
Addition of thiols to styrenes: formation of benzylic thioethers
1989 · M. Belley, R. Zamboni · The Journal of Organic Chemistry · 53
Discovery and Synthesis of a Potent, Selective and Orally Bioavailable EP4 Receptor Agonist
2004 · Robert N. Young, Xavier Billot, et al. · Heterocycles · 52
Development of a novel series of styrylquinoline compounds as high-affinity leukotriene D4 receptor antagonists: synthetic and structure-activity studies leading to the discovery of (.+-.)-3-[[[3-[2-(7-chloro-2-quinolinyl)-(E)-ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid
1992 · R. Zamboni, M. Belley, et al. · Journal of Medicinal Chemistry · 51
Coexpression of full-length gamma-aminobutyric acid(B) (GABA(B)) receptors with truncated receptors and metabotropic glutamate receptor 4 supports the GABA(B) heterodimer as the functional receptor.
2000 · R Sullivan, A Chateauneuf, et al. · PubMed · 49
Differential Effect of a Selective Cyclooxygenase-2 Inhibitor Versus Indomethacin on Renal Blood Flow in Conscious Volume-Depleted Dogs
1998 · Shawn C. Black, Christine Brideau, et al. · Journal of Cardiovascular Pharmacology · 41
Synthesis and SAR of pyrimidine-based, non-nucleotide P2Y14 receptor antagonists
2011 · Daniel Guay, Christian Beaulieu, et al. · Bioorganic & Medicinal Chemistry Letters · 39
Synthesis of the Nanomolar Photoaffinity GABAB Receptor Ligand CGP 71872 Reveals Diversity in the Tissue Distribution of GABAB Receptor Forms
1999 · Michel Belley, Richard Sullivan, et al. · Bioorganic & Medicinal Chemistry · 35
Comparison between two classes of selective EP3 antagonists and their biological activities
2006 · Michel Belley, Chi Chung Chan, et al. · Bioorganic & Medicinal Chemistry Letters · 32
Synthesis and reactivity of N-hydroxy-2-aminoindoles
2005 · Michel Belley, Effiette Sauer, et al. · Tetrahedron Letters · 32
Intramolecular cyclopropanation of enol ethers: synthetic approach to medium-sized carbocycles
1987 · Julian Adams, Richard Frenette, et al. · Journal of the American Chemical Society · 31
The discovery of a new structural class of potent orally active leukotriene D4 antagonists
1992 · M. Labelle, P. Prasit, et al. · Bioorganic & Medicinal Chemistry Letters · 27
A new class of leukotriene biosynthesis inhibitor: the development of MK-0591.
1993 · P Prasit, M Belley, et al. · PubMed · 26
Formation of reactive tricyclic intermediates via the intramolecular cyclopropanation of dihydropyrans. Synthesis of eucalyptol
1986 · Julian Adams, Michel Belley · Tetrahedron Letters · 26
Structure–activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP3 antagonists
2004 · Michel Belley, Michel Gallant, et al. · Bioorganic & Medicinal Chemistry Letters · 25
Works count: 69
Citation count: 2,672
H-index: 25
I10-index: 43
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