Author

Shigeru Akasofu

Observed names: Akasofu Shigeru, Akasofu, Shigeru, S. Akasofu

Institution: Eisai (Japan)

Observed institutions: Prefectural University of Hiroshima, Kyushu University, Kyoto University, Eisai (Japan), Kobe University

OpenAlex ID: A5003751302

Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer’s disease

2020 · Malcolm Roberts, Ioanna Sevastou, et al. · Acta Neuropathologica Communications · 148

Study of neuroprotection of donepezil, a therapy for Alzheimer's disease

2008 · S. Akasofu, M. Kimura, et al. · Chemico-Biological Interactions · 88

Purification and Characterization of a Src-related p57 Protein-tyrosine Kinase from Xenopus Oocytes

1996 · Ken-ichi Sato, Mamoru Aoto, et al. · Journal of Biological Chemistry · 77

Protective effect of donepezil against Aβ(1-40) neurotoxicity in rat septal neurons

2005 · Manami Kimura, Shigeru Akasofu, et al. · Brain Research · 75

Protective effect of donepezil in a primary culture of rat cortical neurons exposed to oxygen–glucose deprivation

2003 · Shigeru Akasofu, Takashi Kosasa, et al. · European Journal of Pharmacology · 72

Preclinical in vivo characterization of lemborexant (E2006), a novel dual orexin receptor antagonist for sleep/wake regulation

2019 · Carsten Theodor Beuckmann, Takashi Ueno, et al. · SLEEP · 53

PE859, a Novel Tau Aggregation Inhibitor, Reduces Aggregated Tau and Prevents Onset and Progression of Neural Dysfunction In Vivo

2015 · Michiaki Okuda, Ichiro Hijikuro, et al. · PLoS ONE · 38

Protective effect of donepezil in primary-cultured rat cortical neurons exposed to N-methyl-d-aspartate (NMDA) toxicity

2006 · Shigeru Akasofu, Manami Kimura, et al. · European Journal of Pharmacology · 28

Donepezil attenuates excitotoxic damage induced by membrane depolarization of cortical neurons exposed to veratridine

2008 · Shigeru Akasofu, Kohei Sawada, et al. · European Journal of Pharmacology · 14

Application of Polymer-Protected Ultrafine Platinum Particles to the Immunological Detection of Human Serum Albumin

1994 · T. Uda, R. Kanmei, et al. · Analytical Biochemistry · 7

P4‐695: E2814: a Novel Anti‐tau Therapeutic Antibody for Alzheimer's Disease

2019 · Malcolm Roberts, Ioanna Sevastou, et al. · Alzheimer s & Dementia · 1

Alzheimer病における受動免疫療法のためのタウの微小管結合反復ドメインを標的とする高親和性抗体,E2814の前臨床特性化【JST・京大機械翻訳】

2020 · Roberts Malcolm, Sevastou Ioanna, et al.

Works count: 15

Citation count: 601

H-index: 9

I10-index: 9