Author

Helga Rübsamen‐Schaeff

Observed names: H Rübsamen-Schaeff, H Rübsamen‐Schaeff, H. Rubsamen-Schaeff, Helga Rübsamen-Schaeff, Rübsamen-Schaeff, Helga, Rübsamen-Schaeff, Helga 1949-

Institution: AiCuris (Germany)

Observed institution: AiCuris (Germany)

OpenAlex ID: A5004530281

Letermovir for Cytomegalovirus Prophylaxis in Hematopoietic-Cell Transplantation

2014 · Roy F. Chemaly, Andrew J. Ullmann, et al. · New England Journal of Medicine · 384

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Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism

2010 · Byung-Gil Lee, Eun Young Park, et al. · Nature Structural & Molecular Biology · 228

First Report of Successful Treatment of Multidrug-Resistant Cytomegalovirus Disease with the Novel Anti-CMV Compound AIC246

2011 · D.R. Kaul, S. Stoelben, et al. · American Journal of Transplantation · 166

Preemptive treatment of Cytomegalovirus infection in kidney transplant recipients with letermovir: results of a Phase 2a study

2013 · Susanne Stoelben, Wolfgang Arns, et al. · Transplant International · 139

AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control

2015 · Malte Gersch, Kirsten Famulla, et al. · Nature Communications · 135

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Pharmacokinetics and Safety of Letermovir Coadministered With Cyclosporine A or Tacrolimus in Healthy Subjects

2017 · Dirk Kropeit, Oliver von Richter, et al. · Clinical Pharmacology in Drug Development · 84

Pharmacokinetics and safety of letermovir, a novel anti‐human cytomegalovirus drug, in patients with renal impairment

2017 · Dirk Kropeit, Jürgen Scheuenpflug, et al. · British Journal of Clinical Pharmacology · 37

Intravenous Hydroxypropyl β‐Cyclodextrin Formulation of Letermovir: A Phase I, Randomized, Single‐Ascending, and Multiple‐Dose Trial

2017 · K Erb‐Zohar, D Kropeit, et al. · Clinical and Translational Science · 31

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Pharmacokinetics and safety of the anti‐human cytomegalovirus drug letermovir in subjects with hepatic impairment

2017 · Dirk Kropeit, David McCormick, et al. · British Journal of Clinical Pharmacology · 30

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First‐in‐Human, Single‐ and Multiple‐Ascending‐Dose, Food‐Effect, and Absolute Bioavailability Trials to Assess the Pharmacokinetics, Safety, and Tolerability of Pritelivir, a Nonnucleoside Helicase‐Primase Inhibitor Against Herpes Simplex Virus in Healthy Subjects

2023 · Dirk Kropeit, Susanne Bonsmann, et al. · Clinical Pharmacology in Drug Development · 18

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Overcoming fragmentation of health research in Europe: lessons from COVID-19

2020 · Karin R Sipido, Fernando Antoñanzas, et al. · The Lancet · 18

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Pharmacokinetics and Safety of Letermovir and Midazolam Coadministration in Healthy Subjects

2021 · Dirk Kropeit, David McCormick, et al. · Clinical Pharmacology in Drug Development · 12

Helicase–Primase Inhibitors as the Potential Next Generation of Highly Active Drugs Against Herpes Simplex Viruses

2011 · Alexander Birkmann, Guy Hewlett, et al. · Future Virology · 12

The T cell-selective IL-2 mutant AIC284 mediates protection in a rat model of Multiple Sclerosis

2015 · Andreas Weishaupt, Daniela Paulsen, et al. · Journal of Neuroimmunology · 11

New Drug Development for Known and Emerging Viruses

2021 · Helga Rübsamen‐Schaeff, Helmut Buschmann · Methods and principles in medicinal chemistry · 10

The Effect of Oral Letermovir Administration on the Pharmacokinetics of a Single Oral Dose of P‐Glycoprotein Substrate Digoxin in Healthy Volunteers

2021 · Jürgen Scheuenpflug, Dirk Kropeit, et al. · Clinical Pharmacology in Drug Development · 7

Wenn Antibiotika nicht mehr helfen

2014 · Helga Rübsamen-Schaeff · BIOspektrum · 1

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Antiviral Strategies Against the Human Cytomegalo Virus

2021 · Helga Rübsamen‐Schaeff · Methods and principles in medicinal chemistry

Front Matter

2021 · Helga Rübsamen-Schaeff, Helmut Buschmann · Methods and principles in medicinal chemistry

From academic research to founding a company: the story of AiCuris

2019 · Helga Rübsamen-Schaeff · Pure and Applied Chemistry

P3.446 Excellent Efficacy of PRITELIVIR (AIC316) in Suppression of Genital Herpes, a Novel Drug Against Herpes Simplex Virus (HSV) Type 1 and 2

2013 · A Birkmann, D McCormick, et al. · Sexually Transmitted Infections

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Works count: 23

Citation count: 1,323

H-index: 12

I10-index: 15