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Kiel Hards

Observed names: Hards, Kiel, Kiel J. Hards
ORCID: 0000-0002-7887-4977
Observed ORCID: 0000-0002-7887-4977
OpenAlex ID: A5004530681
Bactericidal mode of action of bedaquiline
2015 · Kiel Hards, Jennifer R. Robson, et al. · Journal of Antimicrobial Chemotherapy · 228
Energetics of Respiration and Oxidative Phosphorylation in Mycobacteria
2014 · Gregory M. Cook, Kiel Hards, et al. · Microbiology Spectrum · 212
Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection
2017 · Nitin P. Kalia, Erik J. Hasenoehrl, et al. · Proceedings of the National Academy of Sciences · 189
A soil actinobacterium scavenges atmospheric H 2 using two membrane-associated, oxygen-dependent [NiFe] hydrogenases
2014 · Chris Greening, Michael Berney, et al. · Proceedings of the National Academy of Sciences · 153
Persistence of the dominant soil phylum Acidobacteria by trace gas scavenging
2015 · Chris Greening, Carlo R. Carere, et al. · Proceedings of the National Academy of Sciences · 136
Mixotrophy drives niche expansion of verrucomicrobial methanotrophs
2017 · Carlo R Carere, Kiel Hards, et al. · The ISME Journal · 131
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Oxidative Phosphorylation as a Target Space for Tuberculosis: Success, Caution, and Future Directions
2017 · Gregory M. Cook, Kiel Hards, et al. · Microbiology Spectrum · 130
Energetics of Pathogenic Bacteria and Opportunities for Drug Development
2014 · Gregory M. Cook, Chris Greening, et al. · Advances in microbial physiology/Advances in Microbial Physiology · 126
Atmospheric Hydrogen Scavenging: from Enzymes to Ecosystems
2014 · Chris Greening, Philippe Constant, et al. · Applied and Environmental Microbiology · 109
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Targeting bacterial energetics to produce new antimicrobials
2017 · Kiel Hards, Gregory M. Cook · Drug Resistance Updates · 99
Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis
2020 · Bei Shi Lee, Kiel Hards, et al. · EMBO Molecular Medicine · 98
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Essentiality of Succinate Dehydrogenase in Mycobacterium smegmatis and Its Role in the Generation of the Membrane Potential Under Hypoxia
2014 · Ildiko Pecsi, Kiel Hards, et al. · mBio · 94
Ionophoric effects of the antitubercular drug bedaquiline
2018 · Kiel Hards, Duncan G. G. McMillan, et al. · Proceedings of the National Academy of Sciences · 90
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Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering
2020 · Brendon M. Lee, Liam K. Harold, et al. · PLoS Pathogens · 89
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Emerging connections between gut microbiome bioenergetics and chronic metabolic diseases
2021 · Brendan A. Daisley, David Koenig, et al. · Cell Reports · 84
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Pyrazolo[1,5-a]pyridine Inhibitor of the Respiratory Cytochrome bcc Complex for the Treatment of Drug-Resistant Tuberculosis
2018 · Xiaoyun Lu, Zoe Williams, et al. · ACS Infectious Diseases · 84
Three different [ NiFe ] hydrogenases confer metabolic flexibility in the obligate aerobe M ycobacterium smegmatis
2013 · Michael Berney, Chris Greening, et al. · Environmental Microbiology · 68
The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB
2021 · Schara Safarian, Helen K. Opel-Reading, et al. · Nature Communications · 60
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M. tuberculosis relies on trace oxygen to maintain energy homeostasis and survive in hypoxic environments
2023 · Nitin Pal Kalia, Samsher Singh, et al. · Cell Reports · 48
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An amiloride derivative is active against the F1Fo-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis
2022 · Kiel Hards, Chen-Yi Cheung, et al. · Communications Biology · 47
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Activation of type II NADH dehydrogenase by quinolinequinones mediates antitubercular cell death
2016 · Adam Heikal, Kiel Hards, et al. · Journal of Antimicrobial Chemotherapy · 47
Two uptake hydrogenases differentially interact with the aerobic respiratory chain during mycobacterial growth and persistence
2019 · Paul R.F. Cordero, Rhys Grinter, et al. · Journal of Biological Chemistry · 44
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Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2
2020 · Nichaela Harbison-Price, Scott A. Ferguson, et al. · mSphere · 42
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Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis
2019 · Wuan-Geok Saw, Mu-Lu Wu, et al. · Scientific Reports · 35
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The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria
2013 · Matthew B. McNeil, Hannah G. Hampton, et al. · FEBS Letters · 34
Works count: 62
Citation count: 2,888
H-index: 27
I10-index: 43
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