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Samer O. Abdul‐Hay

Observed names: S. Abdul-Hay, Samer Abdul-Hay, Samer Abdul‐Hay, Samer O Abdul-Hay, Samer O. Abdul-Hay, Samer. Abdul-Hay (7958078)
OpenAlex ID: A5005325846
Deletion of Insulin-Degrading Enzyme Elicits Antipodal, Age-Dependent Effects on Glucose and Insulin Tolerance
2011 · Samer O. Abdul-Hay, Dongcheul Kang, et al. · PLoS ONE · 113
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Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin
2010 · Malcolm A. Leissring, Enrico Malito, et al. · PLoS ONE · 108
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ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer’s disease
2014 · Christopher W Medway, Samer Abdul-Hay, et al. · Molecular Neurodegeneration · 82
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Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40
2020 · Caitlin N. Suire, Samer O. Abdul-Hay, et al. · Alzheimer s Research & Therapy · 73
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Identification of BACE2 as an avid ß-amyloid-degrading protease
2012 · Samer O Abdul-Hay, Tomoko Sahara, et al. · Molecular Neurodegeneration · 67
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Optimization of Peptide Hydroxamate Inhibitors of Insulin-Degrading Enzyme Reveals Marked Substrate-Selectivity
2013 · Samer O. Abdul-Hay, Amy L. Lane, et al. · Journal of Medicinal Chemistry · 61
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Characterization of Insulin Degrading Enzyme and Other Amyloid-β Degrading Proteases in Human Serum: A Role in Alzheimer's Disease?
2012 · Zhiheng Liu, Haihao Zhu, et al. · Journal of Alzheimer s Disease · 35
Inhibition of Amyloidogenesis by Nonsteroidal Anti-inflammatory Drugs and Their Hybrid Nitrates
2011 · Isaac T. Schiefer, Samer Abdul-Hay, et al. · Journal of Medicinal Chemistry · 34
Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: In vitro evidence querying the NO donor functionality
2008 · Tareisha Dunlap, Samer O. Abdul-Hay, et al. · Nitric Oxide · 31
Selective Targeting of Extracellular Insulin-Degrading Enzyme by Quasi-Irreversible Thiol-Modifying Inhibitors
2015 · Samer O. Abdul-Hay, Thomas D. Bannister, et al. · ACS Chemical Biology · 26
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Quinone-Induced Activation of Keap1/Nrf2 Signaling by Aspirin Prodrugs Masquerading as Nitric Oxide
2012 · Tareisha Dunlap, Sujeewa C. Piyankarage, et al. · Chemical Research in Toxicology · 23
Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis
2024 · Heather M. Terron, Sagar J. Parikh, et al. · Alzheimer s Research & Therapy · 22
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NO‐flurbiprofen reduces amyloid‐β, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade
2009 · Samer O. Abdul‐Hay, Jia Luo, et al. · Journal of Neurochemistry · 21
Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors
2008 · Srinivas Reddy Chirapu, Boobalan Pachaiyappan, et al. · Bioorganic & Medicinal Chemistry Letters · 21
LRRTM3 Interacts with APP and BACE1 and Has Variants Associating with Late-Onset Alzheimer’s Disease (LOAD)
2013 · Sarah Lincoln, Mariet Allen, et al. · PLoS ONE · 18
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Selective modulation of amyloid‐β peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Aβ levels
2009 · Samer O. Abdul‐Hay, Praneeth Edirisinghe, et al. · Journal of Neurochemistry · 18
Anti-Inflammatory, Antiproliferative, and Cytoprotective Activity of NO Chimera Nitrates of Use in Cancer Chemoprevention
2008 · Ghenet K. Hagos, Samer O. Abdul-Hay, et al. · Molecular Pharmacology · 16
NO-SSRIs: Nitric Oxide Chimera Drugs Incorporating a Selective Serotonin Reuptake Inhibitor
2011 · Samer Abdul-Hay, Isaac T. Schiefer, et al. · ACS Medicinal Chemistry Letters · 15
Age and Its Association with Low Insulin and High Amyloid-β Peptides in Blood
2015 · Huajie Li, Haihao Zhu, et al. · Journal of Alzheimer s Disease · 14
O1‐05‐06: Functional cDNA screening identifies BACE‐2 as a principal beta‐amyloid degrading protease
2011 · Samer Abdul‐Hay, Malcolm Leissring, et al. · Alzheimer s & Dementia · 2
The Blood Glucose-lowering Effect of Racecadotril is not Attributable to Inhibition of Insulin-degrading Enzyme
2013 · S. Kurklinsky, S. Abdul-Hay, et al. · Hormone and Metabolic Research · 1
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Exploring the use of hybrid organic nitrates for the treatment of Alzheimer's disease.
2025 · Samer. Abdul-Hay (7958078) · Figshare
P1‐055: Multiple Abca7 Missense Variants Mined From the Exome Variant Server Show Independent Association With Increased or Decreased Risk of Late‐onset Alzheimer's Disease (load)
2014 · Christopher William Medway, Samer Abdul‐Hay, et al. · Alzheimer s & Dementia
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P1‐292: Correlation between insulin‐degrading enzyme levels and neuropathology in control versus Alzheimer brains with and without cerebral amyloid angiopathy
2010 · Anthony DelleDonne, Richard J. Miles, et al. · Alzheimer s & Dementia
P1–439: NO chimera drugs provide reversal of cognition deficits in animal models: GT 1061 an investigational new drug for Alzheimer's
2006 · Gregory R.J. Thatcher, Brian M. Bennett, et al. · Alzheimer s & Dementia
Works count: 25
Citation count: 801
H-index: 16
I10-index: 19
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