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Hajime Iwagoe

Mapping the human genetic architecture of COVID-19
2021 · COVID-19 Host Genetics Initiative, COVID-19 Host Genetics InitiativeLeadership, et al. · Nature · 990
A second update on mapping the human genetic architecture of COVID-19
2023 · The COVID-19 Host Genetics Initiative, Leadership, et al. · Nature · 127
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Esophageal stimulation by hydrochloric acid causes neurogenic inflammation in the airways in guinea pigs
1997 · Junji Hamamoto, Hirotsugu Kohrogi, et al. · Journal of Applied Physiology · 120
DOCK2 is involved in the host genetics and biology of severe COVID-19
2022 · Ho Namkoong, Ryuya Edahiro, et al. · Nature · 94
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Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity
2023 · Ryuya Edahiro, Yuya Shirai, et al. · Nature Genetics · 68
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Allergen Exposure Induces the Expression of Endothelial Adhesion Molecules in Passively Sensitized Human Bronchus: Time Course and the Role of Cytokines
1998 · Naomi Hirata, Hirotsugu Kohrogi, et al. · American Journal of Respiratory Cell and Molecular Biology · 63
Importation of Dengue Virus Type 3 to Japan from Tanzania and Cote d'Ivoire
2010 · Meng Ling Moi, Tomohiko Takasaki, et al. · Emerging infectious diseases · 60
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Decrease in hemoglobin level predicts increased risk for severe respiratory failure in COVID-19 patients with pneumonia
2020 · Moriyasu Anai, Kimitaka Akaike, et al. · Respiratory Investigation · 59
Clinical Characteristics of Patients with Coronavirus Disease (COVID-19): Preliminary Baseline Report of Japan COVID-19 Task Force, a Nationwide Consortium to Investigate Host Genetics of COVID-19
2021 · Ho Namkoong, Ryuya Edahiro, et al. · International Journal of Infectious Diseases · 56
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Characteristics of hospitalized patients with COVID-19 during the first to fifth waves of infection: a report from the Japan COVID-19 Task Force
2022 · Ho Lee, Shotaro Chubachi, et al. · BMC Infectious Diseases · 46
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The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force
2022 · Qingbo S. Wang, Ryuya Edahiro, et al. · Nature Communications · 42
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Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues
2024 · Yoshihiko Tomofuji, Ryuya Edahiro, et al. · Cell Genomics · 33
Blood DNA virome associates with autoimmune diseases and COVID-19
2025 · Noah Sasa, Shohei Kojima, et al. · Nature Genetics · 26
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Resistance of SARS-CoV-2 variants to neutralization by antibodies induced in convalescent patients with COVID-19
2021 · Yu Kaku, Takeo Kuwata, et al. · Cell Reports · 26
The role of cysteinyl leukotrienes in the pathogenesis of asthma: Clinical study of leukotriene antagonist pranlukast for 1 year in moderate and severe asthma
1999 · Hirotsugu Kohrogi, Hajime Iwagoe, et al. · Respirology · 16
The role of substance P release in the lung with esophageal acid
2001 · Hirotsugu Kohrogi, Junji Hamamoto, et al. · The American Journal of Medicine · 15
Novel Phosphodiesterase 4 Inhibitor T-440 Reverses and Prevents Human Bronchial Contraction Induced by Allergen
1998 · Kazuhiko Fujii, Hirotsugu Kohrogi, et al. · Journal of Pharmacology and Experimental Therapeutics · 15
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution
2025 · Ryuya Edahiro, Go Sato, et al. · Nature Genetics · 13
Host control of persistent Epstein–Barr virus infection
2026 · Axel Schmidt, T. Madhusankha Alawathurage, et al. · Nature · 9
Association of severe COVID-19 outcomes with radiological scoring and cardiomegaly: findings from the COVID-19 inpatients database, Japan
2022 · Atsuhiro Kanayama, Yuuki Tsuchihashi, et al. · Japanese Journal of Radiology · 9
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Evidence that PGF2 alpha-induced contraction of isolated guinea pig bronchi is mediated in part by release of tachykinins
1995 · K. Fujii, H. Kohrogi, et al. · Journal of Applied Physiology · 9
Gastrointestinal symptoms in COVID-19 and disease severity: a Japanese registry-based retrospective cohort study
2024 · Yuta Matsubara, Hiroki Kiyohara, et al. · Journal of Gastroenterology · 7
Tachykinin antagonist FK224 inhibits neurokinin A‐, substance P‐ and capsaicin‐induced human bronchial contraction
1997 · I. Honda, H. Kohrogi, et al. · Fundamental and Clinical Pharmacology · 7
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Evidence That Allergen-Induced Contraction of Guinea Pig Bronchi Is Mediated in Part by the Release of Tachykinins
2009 · Hirotsugu Kohrogi, Tetsuro Yamaguchi, et al. · International Archives of Allergy and Immunology · 6
Multicenter phase II study of the combination of carboplatin and paclitaxel as first line treatment in elderly patients with advanced non small cell lung cancer (NSCLC)
2004 · I. Okamoto, E. Moriyama, et al. · Journal of Clinical Oncology · 6
Works count: 32
Citation count: 1,929
H-index: 15
I10-index: 18
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