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Simone Giovannuzzi

1,5-Diaryl-1,2,4-triazole Ureas as New SLC-0111 Analogues Endowed with Dual Carbonic Anhydrase and VEGFR-2 Inhibitory Activities
2023 · Ahmed E. Elsawi, Mostafa M. Elbadawi, et al. · Journal of Medicinal Chemistry · 74
Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR-2 as Potential Agents for Solid Tumors: X-ray, In Vitro , In Vivo , and In Silico Investigations of Coumarin-Based Thiazoles
2024 · Salma M. Hefny, Tarek F. El-Moselhy, et al. · Journal of Medicinal Chemistry · 58
Discovery of indolinone-bearing benzenesulfonamides as new dual carbonic anhydrase and VEGFR-2 inhibitors possessing anticancer and pro-apoptotic properties
2023 · Samaa Saied, Moataz Shaldam, et al. · European Journal of Medicinal Chemistry · 50
Coumarins effectively inhibit bacterial α-carbonic anhydrases
2022 · Simone Giovannuzzi, Chad S. Hewitt, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 45
Inhibition studies of bacterial α-carbonic anhydrases with phenols
2022 · Simone Giovannuzzi, Chad S. Hewitt, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 28
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Aromatic Sulfonamides including a Sulfonic Acid Tail: New Membrane Impermeant Carbonic Anhydrase Inhibitors for Targeting Selectively the Cancer-Associated Isoforms
2021 · Simone Giovannuzzi, Mario D’Ambrosio, et al. · International Journal of Molecular Sciences · 28
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Dithiocarbamates effectively inhibit the α-carbonic anhydrase from Neisseria gonorrhoeae
2021 · Simone Giovannuzzi, Nader S. Abutaleb, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 28
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Human carbonic anhydrase modulators: the past, present, and future
2025 · Simone Giovannuzzi, Claudiu T. Supuran · Trends in Pharmacological Sciences · 27
Dual Inhibitors of Brain Carbonic Anhydrases and Monoamine Oxidase-B Efficiently Protect against Amyloid-β-Induced Neuronal Toxicity, Oxidative Stress, and Mitochondrial Dysfunction
2024 · Simone Giovannuzzi, Daniel Chavarria, et al. · Journal of Medicinal Chemistry · 27
Boron-containing carbonic anhydrases inhibitors
2023 · Simone Giovannuzzi, Anna Nikitjuka, et al. · Bioorganic Chemistry · 27
Development of pyrazolo[1,5-a]pyrimidine-grafted coumarins as selective carbonic anhydrase inhibitors and tubulin polymerization inhibitors with potent anticancer activity
2025 · Mahmoud S. Elkotamy, Mohamed A. Abdelrahman, et al. · International Journal of Biological Macromolecules · 25
Innovative design and synthesis of dual-acting hCA IX/CDK-2 inhibitors through hetero ring fused pyrimidine utilization for cutting-edge anticancer therapy: Zein nanoparticles for in vivo lung cancer treatment
2025 · Heba M. Abosalim, Tarek F. El-Moselhy, et al. · Bioorganic Chemistry · 24
Novel benzenesulfonamide derivatives linked to diaryl pyrazole tail as potential carbonic anhydrase II/VII inhibitors with anti-epileptic activity
2025 · Wael A.A. Fadaly, Mohamed T.M. Nemr, et al. · European Journal of Medicinal Chemistry · 24
Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors
2025 · Mohamed A. Zeidan, Mahmoud Abdelrahman Alkabbani, et al. · Journal of Medicinal Chemistry · 23
Probing benzenesulfonamide–thiazolidinone hybrids as multitarget directed ligands for efficient control of type 2 diabetes mellitus through targeting the enzymes: α-glucosidase and carbonic anhydrase II
2024 · Mona A. Gamal, Samar H. Fahim, et al. · European Journal of Medicinal Chemistry · 20
Development of isatin-functionalized benzenesulfonamides as novel carbonic anhydrase II and VII inhibitors with antiepileptic potential
2025 · Wagdy M. Eldehna, Anwar A. El-Hamaky, et al. · European Journal of Medicinal Chemistry · 19
Identification of thienopyrimidine derivatives tethered with sulfonamide and other moieties as carbonic anhydrase inhibitors: Design, synthesis and anti-proliferative activity
2024 · Samah Higazy, Nermin Samir, et al. · Bioorganic Chemistry · 19
Development of Penicillin-Based Carbonic Anhydrase Inhibitors Targeting Multidrug-Resistant Neisseria gonorrhoeae
2024 · Alessandro Bonardi, Alessio Nocentini, et al. · Journal of Medicinal Chemistry · 18
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4-(3-Alkyl/benzyl-guanidino)benzenesulfonamides as selective carbonic anhydrase VII inhibitors
2022 · Morteza Abdoli, Simone Giovannuzzi, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 18
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Coumarins inhibit η-class carbonic anhydrase from Plasmodium falciparum
2022 · Simone Giovannuzzi, Viviana De Luca, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 17
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May Sulfonamide Inhibitors of Carbonic Anhydrases from Mammaliicoccus sciuri Prevent Antimicrobial Resistance Due to Gene Transfer to Other Harmful Staphylococci?
2022 · Viviana De Luca, Simone Giovannuzzi, et al. · International Journal of Molecular Sciences · 16
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Redesigning oxazolidinones as carbonic anhydrase inhibitors against vancomycin-resistant enterococci
2025 · Andrea Ammara, Simone Giovannuzzi, et al. · European Journal of Medicinal Chemistry · 15
Benzoxaborinine, New Chemotype for Carbonic Anhydrase Inhibition: Ex Novo Synthesis, Crystallography, In Silico Studies, and Anti-Melanoma Cell Line Activity
2024 · Simone Giovannuzzi, Anna Nikitjuka, et al. · Journal of Medicinal Chemistry · 15
Continued Structural Exploration of Sulfocoumarin as Selective Inhibitor of Tumor-Associated Human Carbonic Anhydrases IX and XII
2022 · Simone Giovannuzzi, Clemente Capasso, et al. · Molecules · 15
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1,2,3‐Triazole‐based esters and carboxylic acids as nonclassical carbonic anhydrase inhibitors capable of cathepsin B inhibition
2023 · Kiran Siwach, Manishita Rani, et al. · Archiv der Pharmazie · 14
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Works count: 117
Citation count: 988
H-index: 18
I10-index: 35
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