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Limo Chen

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
2014 · Limo Chen, Don L. Gibbons, et al. · Nature Communications · 966
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Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer
2019 · Triparna Sen, B. Leticia Rodriguez, et al. · Cancer Discovery · 894
CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade
2018 · Limo Chen, Lixia Diao, et al. · Cancer Discovery · 461
Epithelial–Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma
2016 · Yanyan Lou, Lixia Diao, et al. · Clinical Cancer Research · 438
Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion
2020 · David H. Peng, Bertha Leticia Rodriguez, et al. · Nature Communications · 436
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Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target
2011 · Ting Chen, Duygu Ozel, et al. · Nature Chemical Biology · 120
Tumor suppression by small molecule inhibitors of translation initiation
2012 · Limo Chen, Bertal H Aktas, et al. · Oncotarget · 104
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Th17 cells contribute to combination MEK inhibitor and anti-PD-L1 therapy resistance in KRAS/p53 mutant lung cancers
2021 · David H. Peng, B. Leticia Rodriguez, et al. · Nature Communications · 71
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Twist induces epithelial-mesenchymal transition in cervical carcinogenesis by regulating the TGF-β/Smad3 signaling pathway
2015 · QIONG FAN, MEI-TING QIU, et al. · Oncology Reports · 59
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In vitro inhibition of translation initiation by N,N′-diarylureas—potential anti-cancer agents
2011 · Séverine Denoyelle, Ting Chen, et al. · Bioorganic & Medicinal Chemistry Letters · 55
An essential role for platelet-activating factor in activating mast cell migration following ultraviolet irradiation
2013 · Rommel Chacón-Salinas, Limo Chen, et al. · Journal of Leukocyte Biology · 50
Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression
2016 · Limo Chen, Xiaohui Yi, et al. · OncoImmunology · 42
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KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1
2015 · Mei-Ting Qiu, Qiong Fan, et al. · Oncotarget · 41
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Overexpression of CXC Chemokine Ligand 14 Exacerbates Collagen-Induced Arthritis
2010 · Limo Chen, Linjie Guo, et al. · The Journal of Immunology · 36
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γ-Glutamyl cyclotransferase contributes to tumor progression in high grade serous ovarian cancer by regulating epithelial-mesenchymal transition via activating PI3K/AKT/mTOR pathway
2018 · Yanli Li, Tingting Wu, et al. · Gynecologic Oncology · 31
CD38 as an Immunomodulator in Cancer
2020 · Yanli Li, Rui Yang, et al. · Future Oncology · 30
Synthesis of Rigidified eIF4E/eIF4G Inhibitor-1 (4EGI-1) Mimetic and Their in Vitro Characterization as Inhibitors of Protein–Protein Interaction
2014 · Poornachandran Mahalingam, Khuloud Takrouri, et al. · Journal of Medicinal Chemistry · 28
Synthesis and SAR study of novel 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as potent eIF2·GTP·Met-tRNAiMet ternary complex inhibitors
2013 · Séverine Denoyelle, Ting Chen, et al. · European Journal of Medicinal Chemistry · 27
The mutually regulatory loop of epithelial–mesenchymal transition and immunosuppression in cancer progression
2015 · Limo Chen, John V Heymach, et al. · OncoImmunology · 26
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Reversal of the phenotype by K-ras val12 silencing mediated by adenovirus-delivered siRNA in human pancreatic cancer cell line Panc-1
2005 · Li-Mo Chen · World Journal of Gastroenterology · 26
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Amplification and functional characterization of MUC1 promoter and gene-virotherapy via a targeting adenoviral vector expressing hSSTR2 gene in MUC1-positive Panc-1 pancreatic cancer cells in vitro
2005 · Limo Chen, Qiang Liu, et al. · International Journal of Molecular Medicine · 22
Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance
2023 · B. Leticia Rodriguez, Limo Chen, et al. · Frontiers in Immunology · 19
3‐Substituted Indazoles as Configurationally Locked 4EGI‐1 Mimetics and Inhibitors of the eIF4E/eIF4G Interaction
2014 · Revital Yefidoff‐Freedman, Ting Chen, et al. · ChemBioChem · 18
CD38 as a novel immune checkpoint and a mechanism of resistance to the blockade of the PD-1/PD-L1 axis.
2017 · Limo Chen, Lauren Averett Byers, et al. · Journal of Clinical Oncology · 16
Targeting CD38 to improve anti-PD-1/CTLA-4 combination therapy in lung cancer.
2018 · Limo Chen, Yanli Li, et al. · Journal of Clinical Oncology · 12
Works count: 70
Citation count: 4,039
H-index: 21
I10-index: 25
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