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Kathleen A. Farley

Observed names: Farley, Kathleen, Farley, Kathleen A., K. A. FARLEY, K. A. Farley, Kathleen A Farley, Kathleen Farley
Observed institution: Pfizer (United States)
ORCID: 0000-0001-8935-6852
Observed ORCID: 0000-0001-8935-6852
OpenAlex ID: A5007684792
Delineating the role of cooperativity in the design of potent PROTACs for BTK
2018 · Adelajda Zorba, Chuong Nguyen, et al. · Proceedings of the National Academy of Sciences · 419
A New Resistance Gene, linB , Conferring Resistance to Lincosamides by Nucleotidylation in Enterococcus faecium HM1025
1999 · Bülent Bozdogan, Latifa Berrezouga, et al. · Antimicrobial Agents and Chemotherapy · 180
Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications
2014 · Andreas Maderna, Matthew Doroski, et al. · Journal of Medicinal Chemistry · 136
Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance
2012 · Arthur C. Rand, Siegfried S. F. Leung, et al. · MedChemComm · 132
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19
2024 · Charlotte M. N. Allerton, Joel T. Arcari, et al. · Journal of Medicinal Chemistry · 90
Integrating Intramolecular Hydrogen Bonding (IMHB) Considerations in Drug Discovery Using ΔlogP As a Tool
2013 · Marina Shalaeva, Giulia Caron, et al. · Journal of Medicinal Chemistry · 89
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Discovery of Azetidinyl Ketolides for the Treatment of Susceptible and Multidrug Resistant Community-Acquired Respiratory Tract Infections
2009 · Thomas V. Magee, Sharon L. Ripp, et al. · Journal of Medicinal Chemistry · 54
A New and Useful Method for the Macrocyclization of Linear Peptides
2012 · Allyn T. Londregan, Kathleen A. Farley, et al. · Organic Letters · 52
Non-Uniform Sampling for All: More NMR Spectral Quality, Less Measurement Time.
2017 · Frank Delaglio, Gregory S Walker, et al. · PubMed · 44
Cyclic Peptide Design Guided by Residual Dipolar Couplings, J -Couplings, and Intramolecular Hydrogen Bond Analysis
2019 · Kathleen A. Farley, Ye Che, et al. · The Journal of Organic Chemistry · 37
Discovery of Nirmatrelvir (PF-07321332): A Potent, Orally Active Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Main Protease
2025 · Jamison B. Tuttle, Christophe Allais, et al. · Journal of Medicinal Chemistry · 35
Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss
2023 · Michelle R. Garnsey, Aaron C. Smith, et al. · Journal of Medicinal Chemistry · 33
Comparative pharmacokinetic profile of cyclosporine (CsA) with a decapeptide and a linear analogue
2017 · David A. Price, Heather Eng, et al. · Organic & Biomolecular Chemistry · 33
Increased HMBC Sensitivity for Correlating Poorly Resolved Proton Multiplets to Carbon-13 Using Selective or Semi-selective Pulses
1996 · Ad Bax, Kathleen A. Farley, et al. · Journal of Magnetic Resonance Series A · 30
Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptor
2011 · Vincent Mascitti, Benjamin D. Stevens, et al. · Bioorganic & Medicinal Chemistry Letters · 29
Macrocyclizations for Medicinal Chemistry: Synthesis of Druglike Macrocycles by High-Concentration Ullmann Coupling
2012 · James C. Collins, Kathleen A. Farley, et al. · The Journal of Organic Chemistry · 28
Complete spectroscopic structural characterization of novobiocin, isonovobiocin, decarbamylnovobiocin, 2″‐(o‐Carbamyl)novobiocin, and novobiocin‐2″,3″‐carbonate
1999 · Frank W. Crow, Wayne K. Duholke, et al. · Journal of Heterocyclic Chemistry · 27
Regioselective Hydroarylations and Parallel Kinetic Resolution of Vince Lactam
2013 · Adam S. Kamlet, Cathy Préville, et al. · Angewandte Chemie International Edition · 26
Screening of Compound Libraries for Protein Binding Using Flow-Injection Nuclear Magnetic Resonance Spectroscopy
2002 · Brian J. Stockman, Kathleen A. Farley, et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 26
Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS)
2021 · Anokha S. Ratnayake, Mark E. Flanagan, et al. · Bioorganic & Medicinal Chemistry · 24
Structural basis for CCR6 modulation by allosteric antagonists
2024 · David Jonathan Wasilko, Brian S. Gerstenberger, et al. · Nature Communications · 23
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Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1
2021 · Agustin Casimiro-Garcia, Christophe Allais, et al. · Journal of Medicinal Chemistry · 23
Cross‐Linked Poly‐4‐Acrylomorpholine: A Flexible and Reversibly Compressible Aligning Gel for Anisotropic NMR Analysis of Peptides and Small Molecules in Water
2021 · Kathleen A. Farley, Martin R. M. Koos, et al. · Angewandte Chemie International Edition · 21
Long-range two-dimensional1H-15N heteronuclear shift correlation at natural abundance using GHNMQC. A study of the reverse transcriptase inhibitor delavirdine
1997 · Kathleen A. Farley, Gregory S. Walker, et al. · Magnetic Resonance in Chemistry · 21
Utilizing on‐ and off‐line monitoring tools to follow a kinetic resolution step during flow synthesis
2016 · Kathleen A. Farley, Usa Reilly, et al. · Magnetic Resonance in Chemistry · 19
Works count: 57
Citation count: 1,824
H-index: 22
I10-index: 34
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