Author

Melody Sauerborn

Observed institutions: Netherlands Organisation for Applied Scientific Research, Utrecht University

OpenAlex ID: A5010337176

Immunological mechanism underlying the immune response to recombinant human protein therapeutics

2009 · Melody Sauerborn, Vera Brinks, et al. · Trends in Pharmacological Sciences · 216

Oxidized and Aggregated Recombinant Human Interferon Beta is Immunogenic in Human Interferon Beta Transgenic Mice

2011 · Miranda M. C. van Beers, Melody Sauerborn, et al. · Pharmaceutical Research · 117

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Aggregated Recombinant Human Interferon Beta Induces Antibodies but No Memory in Immune-Tolerant Transgenic Mice

2010 · Miranda M. C. van Beers, Melody Sauerborn, et al. · Pharmaceutical Research · 92

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Hybrid transgenic immune tolerant mouse model for assessing the breaking of B cell tolerance by human interferon beta

2009 · Miranda M.C. van Beers, Melody Sauerborn, et al. · Journal of Immunological Methods · 38

Practical Considerations for the Pharmacokinetic and Immunogenic Assessment of Antibody–Drug Conjugates

2014 · Melody Sauerborn, William van Dongen · BioDrugs · 20

Antibody Response Against Betaferon® in Immune Tolerant Mice: Involvement of Marginal Zone B-cells and CD4+ T-cells and Apparent Lack of Immunological Memory

2012 · Melody Sauerborn, Miranda M. C. van Beers, et al. · Journal of Clinical Immunology · 19

B-1 cells and naturally occurring antibodies: influencing the immunogenicity of recombinant human therapeutic proteins?

2009 · Melody Sauerborn, Huub Schellekens · Current Opinion in Biotechnology · 19

Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin

2014 · Riccardo Torosantucci, Vera Brinks, et al. · Journal of Pharmaceutical Sciences · 17

Natural Antibodies Against Bone Morphogenic Proteins and Interferons in Healthy Donors and in Patients with Infections Linked to Type-1 Cytokine Responses

2011 · Melody Sauerborn, Esther van de Vosse, et al. · Journal of Interferon & Cytokine Research · 12

Development of ADA Against Recombinant Human Interferon Beta in Immune Tolerant Mice Requires Rapid Recruitment of CD4+ T Cells, Induces Formation of Germinal Centers but Lacks Susceptibility for (Most) Adjuvants

2014 · Grzegorz Kijanka, Melody Sauerborn, et al. · Journal of Pharmaceutical Sciences · 8

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The Immunogenicity of Therapeutic Antibodies

2014 · Melody Sauerborn · Wiley eBooks · 6

Is The Tiered Immunogenicity Testing of Biologics The Adequate Approach in Preclinical Development?

2013 · Melody Sauerborn · Bioanalysis · 3

Immunological aspects of antibody formation against recombinant human therapeutics

2010 · Melody Sauerborn · Utrecht University Repository (Utrecht University) · 1

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(Bio) analysis of biosimilars

2016 · Melody Sauerborn

Immunoassays for unwanted and wanted immunogenicity including validation

2015 · Melody Sauerborn · Journal of Vaccines & Vaccination

Use of human protein transgenic animal models for immunogenicity testing and their value for comparative studies of biosimilars

2013 · Melody Sauerborn · Journal of Bioequivalence & Bioavailability

The use of LC/MS to characterize and analyze biosimilars (peptides and proteins)

2013 · Melody Sauerborn · Journal of Bioequivalence & Bioavailability

Immunological aspects of formation of anti-drug antibodies against aggregated protein drugs

2013 · Melody Sauerborn · Journal of Bioequivalence & Bioavailability

Antibody Assays in Animal Research

2011 · Vera Brinks, Francesca Gilli, et al. · Wiley eBooks

Works count: 19

Citation count: 568

H-index: 9

I10-index: 9