Author

Emma D. Wrenn

Observed names: Emma D Wrenn, Emma Wrenn

Institutions: Center for Cancer and Blood Disorders, Seattle Children's Research Institute

Observed institutions: Seattle Children's Hospital, University of Washington, Fred Hutch Cancer Center, Center for Cancer and Blood Disorders, Seattle Children's Research Institute

ORCID: 0000-0002-9643-457X

Observed ORCID: 0000-0002-9643-457X

OpenAlex ID: A5012937907

Regulation of Collective Metastasis by Nanolumenal Signaling

2020 · Emma D. Wrenn, Ami Yamamoto, et al. · Cell · 78

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Mechanisms of breast cancer metastasis

2021 · S. David Nathanson, Michael Detmar, et al. · Clinical & Experimental Metastasis · 67

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The importance of fusion protein activity in Ewing sarcoma and the cell intrinsic and extrinsic factors that regulate it: A review

2022 · April A. Apfelbaum, Emma D. Wrenn, et al. · Frontiers in Oncology · 48

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Collective metastasis: coordinating the multicellular voyage

2021 · Emma Wrenn, Yin Huang, et al. · Clinical & Experimental Metastasis · 41

Cancer-Associated Fibroblast-Like Tumor Cells Remodel the Ewing Sarcoma Tumor Microenvironment

2023 · Emma D. Wrenn, April A. Apfelbaum, et al. · Clinical Cancer Research · 38

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EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma

2022 · April A. Apfelbaum, Feinan Wu, et al. · Clinical Cancer Research · 29

Optimal, Large-Scale Propagation of Mouse Mammary Tumor Organoids

2020 · Emma D. Wrenn, Breanna M. Moore, et al. · Journal of Mammary Gland Biology and Neoplasia · 13

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Autocrine TGFβ2 enforces a transcriptionally hybrid cell state in Ewing sarcoma

2026 · Emma D. Wrenn, Jacob C. Harris, et al. · Science Advances · 5

Carcinoma-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment

2023 · Emma D. Wrenn, April A. Apfelbaum, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5

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Supplementary Table from EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma

2023 · April A. Apfelbaum, Feinan Wu, et al. · 1

FoxP1 “Tspans” Quiescence and Activation of Mammary Stem Cells

2018 · Emma D. Wrenn, Kevin J. Cheung · Developmental Cell · 1

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Menin inhibition impairs metastatic colonization of Ewing sarcoma

2026 · Katherine A. Braun, Nicolas M. Garcia, et al. · JCI Insight

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Author response: Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

2026 · Olivia G Waltner, April A Apfelbaum, et al.

Reviewer #2 (Public review): Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

2026 · Olivia G Waltner, April A Apfelbaum, et al.

Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

2025 · Olivia G Waltner, April A Apfelbaum, et al. · eLife

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Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

2025 · Olivia G Waltner, April A Apfelbaum, et al. · eLife

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Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

2025 · Olivia G. Waltner, April A. Apfelbaum, et al. · eLife

Transcriptional Rewiring of BET Inhibitor Treated Ewing Sarcoma Cells Augments their Dependency on Focal Adhesion Kinase

2025 · Shireen S Ganapathi, Emma D Wrenn, et al. · bioRxiv (Cold Spring Harbor Laboratory)

Abstract C050: Leveraging ECM deposition by CAF-like Ewing sarcoma tumor cells to target micrometastases with matrix-binding VHHs

2024 · Emma D. Wrenn, Jason P. Price, et al. · Cancer Research

Supplementary Table 1 from Cancer-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment