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Zahra Assar

Observed names: Assar, Zahra, Z. Assar
ORCID: 0000-0001-6008-6203
Observed ORCID: 0000-0001-6008-6203
OpenAlex ID: A5013975673
Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety
2019 · Frederick Cohen, James B. Aggen, et al. · ChemMedChem · 76
ERO1-PDI Redox Signaling in Health and Disease
2021 · Vishwanath Jha, Tripti Kumari, et al. · Antioxidants and Redox Signaling · 47
Design, Synthesis, and Structural Characterization of Lysine Covalent BH3 Peptides Targeting Mcl-1
2021 · Luca Gambini, Parima Udompholkul, et al. · Journal of Medicinal Chemistry · 39
Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors
2018 · Melissa C. Holt, Zahra Assar, et al. · Biochemistry · 38
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Crystal structure of wild-type (WT) human Glutamate oxaloacetate transaminase 1 (GOT1)
2018 · Z. Assar, M.C. Holt, et al. · Worldwide Protein Data Bank · 23
Covalent Targeting of Histidine Residues with Aryl Fluorosulfates: Application to Mcl-1 BH3 Mimetics
2024 · Giulia Alboreggia, Parima Udompholkul, et al. · Journal of Medicinal Chemistry · 21
A structural explanation for the mechanism and specificity of plant branching enzymes I and IIb
2021 · Hadi Nayebi Gavgani, Remie Fawaz, et al. · Journal of Biological Chemistry · 21
Histidine-Covalent Stapled Alpha-Helical Peptides Targeting hMcl-1
2024 · Giulia Alboreggia, Parima Udompholkul, et al. · Journal of Medicinal Chemistry · 20
Structures of holo wild-type human cellular retinol-binding protein II (hCRBPII) bound to retinol and retinal
2014 · Zahra Nossoni, Zahra Assar, et al. · Acta Crystallographica Section D Biological Crystallography · 17
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Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches
2019 · Alireza Ghanbarpour, Cody Pinger, et al. · Journal of the American Chemical Society · 16
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Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates
2016 · Zahra Assar, Zahra Nossoni, et al. · Structure · 15
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A Fragment-Based Electrophile-First Approach to Target Histidine with Aryl-Fluorosulfates: Application to hMcl-1
2025 · Giulia Alboreggia, Kendall Muzzarelli, et al. · Journal of Medicinal Chemistry · 6
Small molecule BLVRB redox inhibitor promotes megakaryocytopoiesis and stress thrombopoiesis in vivo
2025 · Natasha M. Nesbitt, Gian Luca Araldi, et al. · Nature Communications · 6
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Regulation of Absorption and Emission in a Protein/Fluorophore Complex
2024 · Elizabeth M. Santos, Ishita Chandra, et al. · ACS Chemical Biology · 6
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Human Cellular Retinol Binding Protein II Forms a Domain‐Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering
2020 · Alireza Ghanbarpour, Elizabeth M. Santos, et al. · ChemBioChem · 6
Identification of a selective pyruvate dehydrogenase kinase 1 (PDHK1) chemical probe by virtual screening
2024 · Mason A. Baber, Mya D. Gough, et al. · European Journal of Medicinal Chemistry · 4
Novel nitric oxide donors are coronary vasodilators that also bind to the papain-like protease of SARS-CoV-2
2024 · John F. Schmedtje, Fred Ciske, et al. · Biomedicine & Pharmacotherapy · 3
Covalent Targeting of Histidine Residues: A Ligand-First Approach
2026 · Giulia Alboreggia, Emma L. Atienza, et al. · Journal of Medicinal Chemistry · 2
Constrained β-Hairpins Targeting the EphA4 Ligand Binding Domain
2024 · Anne Marie Prentiss, Carlo Baggio, et al. · Journal of Medicinal Chemistry · 2
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Abstract 13295: Novel Experimental Therapeutics for COVID-19 Derived From a Nitric Oxide Donor
2020 · John F Schmedtje, Zahra Assar · Circulation · 1
Origin of Chain Length Specificites of Starch Branching Enzyme
2017 · Hadi Nayebi Gavgani, Remie Fawaz, et al. · Biophysical Journal · 1
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Purine nucleotides are competitive inhibitors of apo-GOT1
2025 · Narges Pourmandi, Arjun Jha, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Histidine-covalent alpha-helical peptide (compound 6) targeting hMcl-1
2024 · K.M. Muzzarelli, Z. Assar, et al. · Worldwide Protein Data Bank
Abstract 10067: A Nitric Oxide Donor Binds to SARS-CoV-2 Papain-Like Protease with Therapeutic Implications
2021 · John F Schmedtje, Zahra Assar, et al. · Circulation
Front Cover: Human Cellular Retinol Binding Protein II Forms a Domain‐Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering (ChemBioChem 22/2020)
2020 · Alireza Ghanbarpour, Elizabeth M. Santos, et al. · ChemBioChem
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Works count: 42
Citation count: 370
H-index: 11
I10-index: 11
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