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John T.-A. Hsu

Observed names: J. T.-A. Hsu, J.T.A. Hsu, John Hsu, John T. A. Hsu, John T.-A Hsu, John T.-A.Hsu, John T.A. Hsu, John T.‐A. Hsu, John Tsu-An Hsu
ORCID: 0000-0002-8766-8681
Observed ORCID: 0000-0002-8766-8681
OpenAlex ID: A5014668342
Inhibition of SARS‐CoV 3C‐like Protease Activity by Theaflavin‐3,3′‐digallate (TF3)
2005 · Chia-Nan Chen, Coney P. C. Lin, et al. · Evidence-based Complementary and Alternative Medicine · 244
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Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate
2004 · Chih-Jung Kuo, Ya-Hui Chi, et al. · Biochemical and Biophysical Research Communications · 161
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Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors
2013 · Yi-Hui Peng, Hui-Yi Shiao, et al. · Journal of Medicinal Chemistry · 150
Discovery of M Protease Inhibitors Encoded by SARS-CoV-2
2020 · Hui-Chen Hung, Yi-Yu Ke, et al. · Antimicrobial Agents and Chemotherapy · 108
Strategies of Development of Antiviral Agents Directed Against Influenza Virus Replication
2007 · Hsing-Pang Hsieh, John Hsu · Current Pharmaceutical Design · 102
Evaluation of metal‐conjugated compounds as inhibitors of 3CL protease of SARS‐CoV
2004 · John T.-A. Hsu, Chih-Jung Kuo, et al. · FEBS Letters · 94
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Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents
2008 · Chih-Jung Kuo, Jiun-Jie Shie, et al. · Bioorganic & Medicinal Chemistry · 88
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Structure-Based Drug Design of Novel Aurora Kinase A Inhibitors: Structural Basis for Potency and Specificity
2009 · Mohane Selvaraj Coumar, Jiun-Shyang Leou, et al. · Journal of Medicinal Chemistry · 75
Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells
2006 · Chia-Nan Chen, Hsin-Hsiu Huang, et al. · Cancer Letters · 69
Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid
2010 · H.-C. Hung, T.-C. Chen, et al. · Journal of Antimicrobial Chemotherapy · 65
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Identification of ligand efficient, fragment-like hits from an HTS library: structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity
2014 · Sailu Sarvagalla, Vivek Kumar Singh, et al. · Journal of Computer-Aided Molecular Design · 64
Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening
2015 · Jian-Sung Wu, Shu-Yu Lin, et al. · Journal of Medicinal Chemistry · 62
The Effects of Aβ1-42 Binding to the SARS-CoV-2 Spike Protein S1 Subunit and Angiotensin-Converting Enzyme 2
2021 · John Tsu-An Hsu, Chih-Feng Tien, et al. · International Journal of Molecular Sciences · 51
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Bispecific Antibody Conjugated Manganese-Based Magnetic Engineered Iron Oxide for Imaging of HER2/neu- and EGFR-Expressing Tumors
2015 · Shou-Cheng Wu, Yu-Jen Chen, et al. · Theranostics · 44
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Antiviral Drug Discovery Against SARS-CoV
2006 · Yu-Shan Wu, Wen-Hsing Lin, et al. · Current Medicinal Chemistry · 44
Mycotoxin Patulin Suppresses Innate Immune Responses by Mitochondrial Dysfunction and p62/Sequestosome-1-dependent Mitophagy
2016 · Wan-Ting Tsai, Yin-Chiu Lo, et al. · Journal of Biological Chemistry · 42
Identification, SAR Studies, and X‐ray Co‐crystallographic Analysis of a Novel Furanopyrimidine Aurora Kinase A Inhibitor
2009 · Mohane Selvaraj Coumar, Ming‐Tsung Tsai, et al. · ChemMedChem · 38
Epstein-Barr Virus BALF3 Has Nuclease Activity and Mediates Mature Virion Production during the Lytic Cycle
2014 · Shih-Hsin Chiu, Meng-Chuan Wu, et al. · Journal of Virology · 37
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Zika Virus NS3 Protease Pharmacophore Anchor Model and Drug Discovery
2020 · Nikhil Pathak, Yi-Ping Kuo, et al. · Scientific Reports · 31
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Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold
2008 · Mohane Selvaraj Coumar, Jian-Sung Wu, et al. · Bioorganic & Medicinal Chemistry Letters · 31
BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71
2014 · Arul Balaji Velu, Guang-Wu Chen, et al. · Antiviral Research · 30
Development of an Anti-Influenza Drug Screening Assay Targeting Nucleoproteins with Tryptophan Fluorescence Quenching
2012 · Hui-Chen Hung, Chia-Lin Liu, et al. · Analytical Chemistry · 29
BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses
2009 · S.-R. Shih, J.-T. Horng, et al. · Journal of Antimicrobial Chemotherapy · 27
Sf‐Caspase‐1‐repressed stable cells: resistance to apoptosis and augmentation of recombinant protein production
2007 · Chih‐Chien Lin, John T.‐A. Hsu, et al. · Biotechnology and Applied Biochemistry · 19
Facile Identification of Dual FLT3–Aurora A Inhibitors: A Computer‐Guided Drug Design Approach
2014 · Yung Chang Hsu, Yi‐Yu Ke, et al. · ChemMedChem · 14
Works count: 35
Citation count: 1,794
H-index: 23
I10-index: 30
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