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Lori Capone
Observed names:
Capone, Lori,
L Capone,
L. Capone
Institution:
Celgene (United States)
Observed institution:
Celgene (United States)
OpenAlex ID:
A5015956946
Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis
2009
·
PH Schafer
, A Parton
, et al.
·
British Journal of Pharmacology
·
426
PDF
Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity
2014
·
P.H. Schafer
, A. Parton
, et al.
·
Cellular Signalling
·
315
PDF
Dexamethasone Synergizes with Lenalidomide to Inhibit Multiple Myeloma Tumor Growth, But Reduces Lenalidomide-Induced Immunomodulation of T and NK Cell Function
2010
·
A. K. Gandhi
, J. Kang
, et al.
·
Current Cancer Drug Targets
·
176
Absorption, metabolism and excretion of [14C]pomalidomide in humans following oral administration
2012
·
Matthew Hoffmann
, Claudia Kasserra
, et al.
·
Cancer Chemotherapy and Pharmacology
·
125
PDF
Spebrutinib (CC-292) Affects Markers of B Cell Activation, Chemotaxis, and Osteoclasts in Patients with Rheumatoid Arthritis: Results from a Mechanistic Study
2019
·
Peter H. Schafer
, Alan J. Kivitz
, et al.
·
Rheumatology and Therapy
·
71
PDF
Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity
2012
·
Alexander L. Ruchelman
, Hon-Wah Man
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
61
Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity
2017
·
Yumi Nakayama
, Jolanta Kosek
, et al.
·
The Journal of Immunology
·
55
PDF
Disposition, metabolism and mass balance of [ 14 C]apremilast following oral administration
2011
·
Matthew Hoffmann
, Gondi Kumar
, et al.
·
Xenobiotica
·
52
PDF
CC-122 Is a Novel Pleiotropic Pathway Modifier with Potent in Vitro Immunomodulatory and Anti-Angiogenic Properties and in Vivo Anti-Tumor Activity in Hematological Cancers.
2012
·
Anita K Gandhi
, Derek Mendy
, et al.
·
Blood
·
8
Opposing Effects of Dexamethasone on Lenalidomide Activity in Multiple Myeloma: Additive/Synergistic Effects on Anti-Proliferative Activity on Myeloma Cells and Antagonistic Effects on Immune Function
2008
·
Peter H Schafer
, Anita K Gandhi
, et al.
·
Blood
·
6
Anti-Proliferative and Apoptotic Activity of Lenalidomide in Combination with Rituximab in Follicular Lymphoma: An in Vitro and Ex Vivo Analysis in Follicular Lymphoma Cells.
2009
·
Anita K Gandhi
, Jian Kang
, et al.
·
Blood
·
3
Targeting Cereblon with the High Affinity Immunomodulatory Compound CC-220: A Novel Therapeutic Agent for B Cell Dyscrasias
2012
·
Peter H Schafer
, Emily Rychak
, et al.
·
Blood
·
2
SAT0028 Aiolos overexpression in systemic lupus erythematosus b-cell subtypes and baff induced memory b-cell differentiation are reduced by cc-220 modulation of cereblon activity
2017
·
GE Ringheim
, J Kosek
, et al.
·
Annals of the Rheumatic Diseases
·
1
PDF
SAT0035 Inhibition of protein kinase c theta by the selective inhibitor cc-90005 induces t cell anergy
2017
·
EM Hur
, L Capone
, et al.
·
Annals of the Rheumatic Diseases
PDF
Inhibition of B Cell Differentiation to the Plasmablast and Plasma Cell Lineage by CC-220, a Potent Modulator of the CRBN E3 Ubiquitin Ligase Complex
2012
·
Peter H Schafer
, Lori Capone
, et al.
·
Blood
B444 Opposing Effects of Dexamethasone on Lenalidomide Activity in Multiple Myeloma
2009
·
PH Schafer
, AK Gandhi
, et al.
·
Clinical Lymphoma & Myeloma
Antiproliferative Effects of Lenalidomide in Combination with Chemotherapeutic Agents in Lymphoma Cell Lines
2008
·
Anita K Gandhi
, Jian Kang
, et al.
·
Blood
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Works count:
18
Citation count:
1,301
H-index:
8
I10-index:
8
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