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Nuno J. Machado
Observed names:
Nuno J Machado,
Nuno Jesus Machado,
Nuno Machado
Institutions:
Centro de Inovação em Biomedicina e Biotecnologia,
University of Coimbra
Observed institutions:
McGovern Institute for Brain Research,
Universidade Federal do Ceará,
Centro de Neurociências e Biologia Celular,
Centro de Inovação em Biomedicina e Biotecnologia,
Massachusetts Institute of Technology,
University of Coimbra
show all 6
ORCID:
0000-0001-5097-4231
Observed ORCID:
0000-0001-5097-4231
OpenAlex ID:
A5016540306
Adenosine A2AReceptor Blockade Prevents Synaptotoxicity and Memory Dysfunction Caused by β-Amyloid Peptides via p38 Mitogen-Activated Protein Kinase Pathway
2009
·
Paula M. Canas
, Lisiane O. Porciúncula
, et al.
·
Journal of Neuroscience
·
374
PDF
Caffeine acts through neuronal adenosine A 2A receptors to prevent mood and memory dysfunction triggered by chronic stress
2015
·
Manuella P. Kaster
, Nuno J. Machado
, et al.
·
Proceedings of the National Academy of Sciences
·
327
PDF
Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice
2013
·
Carla G. Silva
, Christine Métin
, et al.
·
Science Translational Medicine
·
183
Astrocytic Adenosine A2A Receptors Control the Amyloid-β Peptide-Induced Decrease of Glutamate Uptake
2012
·
Marco Matos
, Elisabete Augusto
, et al.
·
Journal of Alzheimer s Disease
·
144
Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease
2014
·
Daniel Rial
, Adalberto A. Castro
, et al.
·
PLoS ONE
·
128
PDF
Caffeine regulates frontocorticostriatal dopamine transporter density and improves attention and cognitive deficits in an animal model of attention deficit hyperactivity disorder
2012
·
Pablo Pandolfo
, Nuno J. Machado
, et al.
·
European Neuropsychopharmacology
·
123
Investigating Drug-induced Mitochondrial Toxicity: A Biosensor to Increase Drug Safety?
2009
·
Claudia Pereira
, Ana Moreira
, et al.
·
Current Drug Safety
·
108
PDF
Liraglutide Protects Against Brain Amyloid-β1–42 Accumulation in Female Mice with Early Alzheimer’s Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation
2020
·
Ana I. Duarte
, Emanuel Candeias
, et al.
·
International Journal of Molecular Sciences
·
94
Adenosine A2A Receptors in the Amygdala Control Synaptic Plasticity and Contextual Fear Memory
2016
·
Ana Patrícia Simões
, Nuno J Machado
, et al.
·
Neuropsychopharmacology
·
93
Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease
2018
·
António C. Silva
, Cristina Lemos
, et al.
·
Neurobiology of Disease
·
90
Type 2 Diabetic and Alzheimer's Disease Mice Present Similar Behavioral, Cognitive, and Vascular Anomalies
2013
·
Cristina Carvalho
, Nuno Machado
, et al.
·
Journal of Alzheimer s Disease
·
88
Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions
2018
·
Paula M. Canas
, Lisiane O. Porciúncula
, et al.
·
eNeuro
·
79
PDF
Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses
2016
·
Nuno J. Machado
, Ana Patrícia Simões
, et al.
·
Molecular Neurobiology
·
66
Central Ghrelin Resistance Permits the Overconsolidation of Fear Memory
2016
·
Elia S. Harmatz
, Lauren Stone
, et al.
·
Biological Psychiatry
·
61
The role of parkinson's disease‐associated receptor GPR 37 in the hippocampus: functional interplay with the adenosinergic system
2015
·
João P. Lopes
, Xavier Morató
, et al.
·
Journal of Neurochemistry
·
57
PDF
Crosstalk Between ATP-P2X7 and Adenosine A2A Receptors Controlling Neuroinflammation in Rats Subject to Repeated Restraint Stress
2021
·
Liliana Dias
, Cátia R. Lopes
, et al.
·
Frontiers in Cellular Neuroscience
·
44
PDF
Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of attentional deficit and hyperactivity disorder
2019
·
Douglas T. Leffa
, Samira G. Ferreira
, et al.
·
European Journal of Neuroscience
·
39
Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision Making
2018
·
Douglas T. Leffa
, Pablo Pandolfo
, et al.
·
Frontiers in Molecular Neuroscience
·
26
PDF
Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer’s Disease
2021
·
Sónia C. Correia
, Nuno J. Machado
, et al.
·
International Journal of Molecular Sciences
·
25
PDF
Imidazole alkaloids inhibit the pro-inflammatory mechanisms of human neutrophil and exhibit anti-inflammatory properties in vivo
2019
·
Talita Magalhães Rocha
, Nuno J Machado
, et al.
·
Journal of Pharmacy and Pharmacology
·
21
Impact of Coffee Intake on Measures of Wellbeing in Mice
2024
·
Nuno J. Machado
, Ana Paula Ardais
, et al.
·
Nutrients
·
17
PDF
Antineuroinflammatory Effect of Amburana cearensis and Its Molecules Coumarin and Amburoside A by Inhibiting the MAPK Signaling Pathway in LPS‐Activated BV‐2 Microglial Cells
2022
·
Ana Bruna de Araújo
, Francisco Vinícius Clemente Serra Azul
, et al.
·
Oxidative Medicine and Cellular Longevity
·
11
PDF
Medicinal Plants Containing Coumarin or Essential Oils from the Brazilian Biome May be New Option for Treating Leishmaniasis?
2021
·
Elizama Shirley Silveira
, Naya Lúcia De Castro Rodrigues
, et al.
·
Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review
·
10
Mitochondria as a Biosensor for Drug-induced Toxicity – Is It Really Relevant?
2011
·
Oliveira
, Ana Moreira
, et al.
·
InTech eBooks
·
5
PDF
Neuroprotective effects of proanthocyanidins of grape seed extracts against oxidative stress and apoptosis induced by 6-hydroxydopamine in PC12 cells
2021
·
Patricia de Araújo Rodrigues
, Selene Maia de Morais
, et al.
·
Conjecturas
·
4
PDF
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Works count:
28
Citation count:
2,217
H-index:
20
I10-index:
23
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