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Kohei Sawada

International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment
2018 · Ksenia Blinova, Qianyu Dang, et al. · Cell Reports · 390
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A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm
2015 · Bernard Fermini, Jules C. Hancox, et al. · SLAS DISCOVERY · 307
A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes
2016 · Hiroyuki Ando, Takashi Yoshinaga, et al. · Journal of Pharmacological and Toxicological Methods · 185
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Differential nociceptive responses in mice lacking the α1B subunit of N-type Ca2+ channels
2001 · Shinji Hatakeyama, Minoru Wakamori, et al. · Neuroreport · 157
Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes
2015 · Keiichi Asakura, Seiji Hayashi, et al. · Journal of Pharmacological and Toxicological Methods · 152
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Functional disorders of the sympathetic nervous system in mice lacking the α 1B subunit (Ca v 2.2) of N-type calcium channels
2001 · Mitsuhiro Ino, Takashi Yoshinaga, et al. · Proceedings of the National Academy of Sciences · 146
Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential
2016 · Wataru Yamamoto, Keiichi Asakura, et al. · PLoS ONE · 90
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Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
2015 · Jun-ichi Okada, Takashi Yoshinaga, et al. · Science Advances · 87
Study of neuroprotection of donepezil, a therapy for Alzheimer's disease
2008 · S. Akasofu, M. Kimura, et al. · Chemico-Biological Interactions · 87
Development of torsadogenic risk assessment using human induced pluripotent stem cell-derived cardiomyocytes: Japan iPS Cardiac Safety Assessment (JiCSA) update
2018 · Yasunari Kanda, Daiju Yamazaki, et al. · Journal of Pharmacological Sciences · 84
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Omega-agatoxin-TK containing D-serine at position 46, but not synthetic omega-[L-Ser46]agatoxin-TK, exerts blockade of P-type calcium channels in cerebellar Purkinje neurons.
1994 · M Kuwada, T Teramoto, et al. · Molecular Pharmacology · 83
Assessment of Testing Methods for Drug-Induced Repolarization Delay and Arrhythmias in an iPS Cell–Derived Cardiomyocyte Sheet: Multi-site Validation Study
2014 · Yuji Nakamura, Junko Matsuo, et al. · Journal of Pharmacological Sciences · 76
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Protective effect of donepezil against Aβ(1-40) neurotoxicity in rat septal neurons
2005 · Manami Kimura, Shigeru Akasofu, et al. · Brain Research · 75
Histiocyte reaction in rabbit femurs to UHMWPE, metal, and ceramic particles in different sizes
1999 · Toshikazu Kubo, Kohei Sawada, et al. · Journal of Biomedical Materials Research · 65
Role of Glutamate Receptors and Voltage-Dependent Calcium and Sodium Channels in the Extracellular Glutamate/Aspartate Accumulation and Subsequent Neuronal Injury Induced by Oxygen/Glucose Deprivation in Cultured Hippocampal Neurons
1998 · Manami Kimura, Kohei Sawada, et al. · Journal of Pharmacology and Experimental Therapeutics · 61
Deep learning-based quality control of cultured human-induced pluripotent stem cell-derived cardiomyocytes
2019 · Ken Orita, Kohei Sawada, et al. · Journal of Pharmacological Sciences · 55
Low-density plating is sufficient to induce cardiac hypertrophy and electrical remodeling in highly purified human iPS cell-derived cardiomyocytes
2013 · Mai Uesugi, Atsuko Ojima, et al. · Journal of Pharmacological and Toxicological Methods · 48
Two types of calcium channels sensitive to ω-agatoxin-TK in cultured rat hippocampal neurones
1995 · T. Teramoto, T. Niidome, et al. · Neuroreport · 44
Design, synthesis, and characterization of BK channel openers based on oximation of abietane diterpene derivatives
2010 · Yong-Mei Cui, Eriko Yasutomi, et al. · Bioorganic & Medicinal Chemistry · 37
A novel method of selecting human embryonic stem cell-derived cardiomyocyte clusters for assessment of potential to influence QT interval
2011 · Kazuto Yamazaki, Taro Hihara, et al. · Toxicology in Vitro · 36
K+-Channel Openers Suppress Epileptiform Activities Induced by 4-Aminopyridine in Cultured Rat Hippocampal Neurons
2008 · Kiyoaki Kobayashi, Yukio Nishizawa, et al. · Journal of Pharmacological Sciences · 32
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Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway
2017 · Takayuki Kimura, Mai Uesugi, et al. · Toxicology and Applied Pharmacology · 31
Novel ATP-Competitive MEK Inhibitor E6201 Is Effective against Vemurafenib-Resistant Melanoma Harboring the MEK1-C121S Mutation in a Preclinical Model
2014 · Yusuke Narita, Kiyoshi Okamoto, et al. · Molecular Cancer Therapeutics · 31
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Establishment of a Human Neuronal Network Assessment System by Using a Human Neuron/Astrocyte Co-Culture Derived from Fetal Neural Stem/Progenitor Cells
2015 · Kazuyuki Fukushima, Yuji Miura, et al. · SLAS DISCOVERY · 29
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Protective effect of donepezil in primary-cultured rat cortical neurons exposed to N-methyl-d-aspartate (NMDA) toxicity
2006 · Shigeru Akasofu, Manami Kimura, et al. · European Journal of Pharmacology · 28
Works count: 106
Citation count: 2,803
H-index: 26
I10-index: 43
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