Author

Alex Chia Yu Chang

Observed names: Alex Chia Yu Chang, Alex C Chang, Alex C Y Chang, Alex C-Y Chang, Alex C. Chang, Alex C. Y. Chang, Alex C.Y. Chang, Alex CY Chang, Alex CY. Chang, Alex Chang, Alex C Y Chang, Alex C.Y. Chang, Andrew C. H. Chang, CHANG Alex Chia Yu, Chang, Alex Chia Yu

Institutions: Shanghai Jiao Tong University, Shanghai Ninth People's Hospital, Stanford Medicine, Institute for Stem Cell Biology and Regenerative Medicine, Stanford Cardiovascular Institute, Stanford University

Observed institutions: BC Cancer Agency, University of British Columbia, Shanghai Jiao Tong University, Shanghai Ninth People's Hospital, Canada's Michael Smith Genome Sciences Centre, Stanford Medicine, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Institute for Stem Cell Biology and Regenerative Medicine, Stanford Cardiovascular Institute, Stanford University

ORCID: 0000-0001-9441-4033

Observed ORCID: 0000-0001-9441-4033

OpenAlex ID: A5016780098

Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

2016 · Paul W Burridge, Yong Fuga Li, et al. · Nature Medicine · 742

Hydrogen sulfide protects cardiomyocytes from doxorubicin-induced ferroptosis through the SLC7A11/GSH/GPx4 pathway by Keap1 S-sulfhydration and Nrf2 activation

2024 · Hui Zhang, Hui Zhang, et al. · Redox Biology · 229

Notch Initiates the Endothelial-to-Mesenchymal Transition in the Atrioventricular Canal through Autocrine Activation of Soluble Guanylyl Cyclase

2011 · Alex C.Y. Chang, YangXin Fu, et al. · Developmental Cell · 164

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Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development

2012 · Victoria C. Garside, Alex C. Chang, et al. · Cellular and Molecular Life Sciences · 159

Humanizing the mdx mouse model of DMD: the long and the short of it

2018 · Nora Yucel, Alex C. Chang, et al. · npj Regenerative Medicine · 145

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Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients

2019 · Haodi Wu, Huaxiao Yang, et al. · European Heart Journal · 135

A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles

2019 · Joe Z. Zhang, Vittavat Termglinchan, et al. · Cell stem cell · 127

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Differential Regulation of Transforming Growth Factor β Signaling Pathways by Notch in Human Endothelial Cells

2009 · YangXin Fu, Alex Chang, et al. · Journal of Biological Chemistry · 113

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Telomere shortening is a hallmark of genetic cardiomyopathies

2018 · Alex C. Y. Chang, Andrew C. H. Chang, et al. · Proceedings of the National Academy of Sciences · 90

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Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy

2016 · Alex Chia Yu Chang, Sang-Ging Ong, et al. · Proceedings of the National Academy of Sciences · 81

Delivery of mitochondria confers cardioprotection through mitochondria replenishment and metabolic compliance

2023 · Alian Zhang, Yangyang Liu, et al. · Molecular Therapy · 75

The Imbalance of p53–Park7 Signaling Axis Induces Iron Homeostasis Dysfunction in Doxorubicin‐Challenged Cardiomyocytes

2023 · Jianan Pan, Weiyao Xiong, et al. · Advanced Science · 73

A highly specific CRISPR-Cas12j nuclease enables allele-specific genome editing

2023 · Yao Wang, Yao Wang, et al. · Science Advances · 52

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Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes

2021 · Alex C.Y. Chang, Gaspard Pardon, et al. · Stem Cell Reports · 52

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Silencing of MYH7 ameliorates disease phenotypes in human iPSC-cardiomyocytes

2020 · Alexandra Dainis, Kathia Zaleta-Rivera, et al. · Physiological Genomics · 52

Intercellular mitochondrial component transfer triggers ischemic cardiac fibrosis

2023 · Chan Zhang, Hao Hao, et al. · 中国科学通报：英文版 · 50

Association of Metformin with the Mortality and Incidence of Cardiovascular Events in Patients with Pre-existing Cardiovascular Diseases

2022 · Tian Li, Rui Providencia, et al. · Drugs · 46

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RUNX3 Maintains the Mesenchymal Phenotype after Termination of the Notch Signal

2011 · YangXin Fu, Alex Chia Yu Chang, et al. · Journal of Biological Chemistry · 44

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Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition

2018 · Victoria N. Parikh, Jing Liu, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 42

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Mitochondrial Amount Determines Doxorubicin‐Induced Cardiotoxicity in Cardiomyocytes

2025 · Weiyao Xiong, Bin Li, et al. · Advanced Science · 40

p53‐Dependent Mitochondrial Compensation in Heart Failure With Preserved Ejection Fraction

2022 · Xiaonan Chen, Hao Lin, et al. · Journal of the American Heart Association · 37

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Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

2019 · Pablo Cordero, Victoria N. Parikh, et al. · Nature Communications · 36

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A Notch‐dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion

2014 · Alex C.Y. Chang, Victoria C. Garside, et al. · Developmental Dynamics · 35

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Targeting Rab7‐Rilp Mediated Microlipophagy Alleviates Lipid Toxicity in Diabetic Cardiomyopathy

2024 · Jiahan Ke, Jianan Pan, et al. · Advanced Science · 32

Pharmacological Silencing of MicroRNA-152 Prevents Pressure Overload–Induced Heart Failure

2020 · Thomas J. LaRocca, Timon Seeger, et al. · Circulation Heart Failure · 30

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Works count: 100

Citation count: 3,096

H-index: 27

I10-index: 42