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Herbert Binch

Observed names: H Binch, Herbert Binch, III
OpenAlex ID: A5019281136
Identification of the primary muscarinic autoreceptor subtype in rat striatum as m2 through a correlation of in vivo microdialysis and in vitro receptor binding data.
1995 · W Billard, H Binch, et al. · Journal of Pharmacology and Experimental Therapeutics · 103
Design and synthesis of piperidinyl piperidine analogues as potent and selective M2 muscarinic receptor antagonists
2000 · Yuguang Wang, Samuel Chackalamannil, et al. · Bioorganic & Medicinal Chemistry Letters · 96
SCH 57790, a selective muscarinic M2 receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals
2001 · Galen J. Carey, William Billard, et al. · European Journal of Pharmacology · 74
Muscarinic agonists and antagonists in the treatment of Alzheimer's disease
2001 · W Greenlee, J Clader, et al. · Il Farmaco · 73
Facilitation of acetylcholine release and improvement in cognition by a selective M2 muscarinic antagonist, SCH 72788
2001 · Jean E. Lachowicz, Ruth A. Duffy, et al. · Life Sciences · 38
Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity
2003 · John W Clader, William Billard, et al. · Bioorganic & Medicinal Chemistry · 27
Substituted 2-(R)-Methyl piperazines as muscarinic M2 selective ligands
2002 · Joseph A Kozlowski, Guowei Zhou, et al. · Bioorganic & Medicinal Chemistry Letters · 20
Diphenylsulfone muscarinic antagonists: piperidine derivatives with high m2 selectivity and improved potency
2000 · William Billard, Herbert Binch, et al. · Bioorganic & Medicinal Chemistry Letters · 17
Diphenyl sulfoxides as selective antagonists of the muscarinic M2 receptor
2000 · Joseph A Kozlowski, Derek B Lowe, et al. · Bioorganic & Medicinal Chemistry Letters · 16
Benzylidene ketal derivatives as M2 muscarinic receptor antagonists
2000 · Craig D Boyle, Samuel Chackalamannil, et al. · Bioorganic & Medicinal Chemistry Letters · 13
Metabolic stabilization of benzylidene ketal M2 muscarinic receptor antagonists via halonaphthoic acid substitution
2001 · Craig D. Boyle, Samuel Chackalamannil, et al. · Bioorganic & Medicinal Chemistry Letters · 10
Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M2 muscarinic receptor antagonists via benzamide modification
2002 · Craig D. Boyle, Susan F. Vice, et al. · Bioorganic & Medicinal Chemistry Letters · 7
Sch 226206 A potent, selective and orally efficacious M2 muscarinic receptor antagonist for the treatment of Alzheimers disease
2002 · Yuguang Wang, Samuel Chackalamannil, et al. · Abstracts of papers - American Chemical Society
Works count: 13
Citation count: 494
H-index: 10
I10-index: 11
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