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Sharon L. Ripp
Observed names:
Ripp, S.L.,
S L Ripp,
Sharon L Ripp,
Sharon Ripp
Institution:
Pfizer (United States)
Observed institutions:
University of Wisconsin–Madison,
University of Louisville,
Pfizer (United States),
National Institute of Environmental Health Sciences
ORCID:
0009-0003-1056-8716
Observed ORCID:
0009-0003-1056-8716
OpenAlex ID:
A5020100940
Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks
2012
·
Suvi T. M. Orr
, Sharon L. Ripp
, et al.
·
Journal of Medicinal Chemistry
·
230
In Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America Perspective
2009
·
Valeria Chu
, Heidi J. Einolf
, et al.
·
Drug Metabolism and Disposition
·
162
Use of Immortalized Human Hepatocytes to Predict the Magnitude of Clinical Drug-Drug Interactions Caused by CYP3A4 Induction
2006
·
Sharon L. Ripp
, Jessica B. Mills
, et al.
·
Drug Metabolism and Disposition
·
121
Deuterium Isotope Effects on Drug Pharmacokinetics. I. System-Dependent Effects of Specific Deuteration with Aldehyde Oxidase Cleared Drugs
2011
·
Raman Sharma
, Timothy J. Strelevitz
, et al.
·
Drug Metabolism and Disposition
·
117
Transcriptional Suppression of Cytochrome P450 Genes by Endogenous and Exogenous Chemicals
2004
·
David S. Riddick
, Chunja Lee
, et al.
·
Drug Metabolism and Disposition
·
97
Evaluation of models for predicting drug–drug interactions due to induction
2010
·
Odette A Fahmi
, Sharon L Ripp
·
Expert Opinion on Drug Metabolism & Toxicology
·
82
Species and Sex Differences in Expression of Flavin-Containing Monooxygenase Form 3 in Liver and Kidney Microsomes
1999
·
Sharon L. Ripp
, Kiyoshi Itagaki
, et al.
·
Drug Metabolism and Disposition
·
81
DHEA metabolites activate estrogen receptors alpha and beta
2012
·
Kristy K. Michael Miller
, Numan Al-Rayyan
, et al.
·
Steroids
·
77
Stereo- and Regioselectivity Account for the Diversity of Dehydroepiandrosterone (dhea) Metabolites Produced by Liver Microsomal Cytochromes P450
2004
·
Kristy K. Michael Miller
, Jian Cai
, et al.
·
Drug Metabolism and Disposition
·
73
Oxidation of Cysteine S-Conjugates by Rabbit Liver Microsomes and cDNA-Expressed Flavin-Containing Mono-oxygenases: Studies withS-(1,2-Dichlorovinyl)-l-cysteine,S-(1,2,2-Trichlorovinyl)-l-cysteine,S-Allyl-l-cysteine, andS-Benzyl-l-cysteine
1997
·
Sharon L. Ripp
, Lila H. Overby
, et al.
·
Molecular Pharmacology
·
72
Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11β-hydroxysteroid dehydrogenases?
2003
·
Boaz Robinzon
, Kristy K Michael
, et al.
·
Archives of Biochemistry and Biophysics
·
70
Induction of CYP3A Expression by Dehydroepiandrosterone: Involvement of the Pregnane X Receptor
2002
·
Sharon L. Ripp
, Jennifer L. Fitzpatrick
, et al.
·
Drug Metabolism and Disposition
·
60
Discovery of Azetidinyl Ketolides for the Treatment of Susceptible and Multidrug Resistant Community-Acquired Respiratory Tract Infections
2009
·
Thomas V. Magee
, Sharon L. Ripp
, et al.
·
Journal of Medicinal Chemistry
·
54
A Rational Chemical Intervention Strategy To Circumvent Bioactivation Liabilities Associated with a Nonpeptidyl Thrombopoietin Receptor Agonist Containing a 2-Amino-4-arylthiazole Motif
2007
·
Amit S. Kalgutkar
, James Driscoll
, et al.
·
Chemical Research in Toxicology
·
54
Metabolism of DHEA by Cytochromes P450 in Rat and Human Liver Microsomal Fractions
2001
·
Jennifer L. Fitzpatrick
, Sharon L. Ripp
, et al.
·
Archives of Biochemistry and Biophysics
·
50
Methionine S-Oxidation in Human and Rabbit Liver Microsomes: Evidence for a High-Affinity Methionine S-Oxidase Activity That Is Distinct from Flavin-Containing Monooxygenase 3
1999
·
Sharon L. Ripp
, Kiyoshi Itagaki
, et al.
·
Archives of Biochemistry and Biophysics
·
47
Oxidative Metabolism of Seleno- l -methionine to l -Methionine Selenoxide by Flavin-Containing Monooxygenases
2006
·
Renee J. Krause
, Steven C. Glocke
, et al.
·
Chemical Research in Toxicology
·
39
Modulation of Receptor Phosphorylation Contributes to Activation of Peroxisome Proliferator Activated Receptor α by Dehydroepiandrosterone and Other Peroxisome Proliferators
2007
·
Viola Tamasi
, Kristy K. Michael Miller
, et al.
·
Molecular Pharmacology
·
36
Dehydroepiandrosterone Affects the Expression of Multiple Genes in Rat Liver Including 11β-Hydroxysteroid Dehydrogenase Type 1: A cDNA Array Analysis
2003
·
Shi Gu
, Sharon L Ripp
, et al.
·
Molecular Pharmacology
·
34
Characterization of the MethionineS-Oxidase Activity of Rat Liver and Kidney Microsomes: Immunochemical and Kinetic Evidence for FMO3 Being the Major Catalyst
1996
·
Renee J. Krause
, Sharon L. Ripp
, et al.
·
Archives of Biochemistry and Biophysics
·
34
Regulation of CYP2C11 by Dehydroepiandrosterone and Peroxisome Proliferators: Identification of the Negative Regulatory Region of the Gene
2003
·
Sharon L Ripp
, K. Cameron Falkner
, et al.
·
Molecular Pharmacology
·
28
Molecular regulation of genes encoding xenobiotic-metabolizing enzymes: mechanisms involving endogenous factors.
2001
·
R N Hines
, Z Luo
, et al.
·
PubMed
·
24
Comparative nonclinical assessments of the biosimilar PF-06410293 and originator adalimumab
2020
·
Mazin Derzi
, Ahmed M. Shoieb
, et al.
·
Regulatory Toxicology and Pharmacology
·
21
PDF
The Time to Move Cytochrome P450 Induction into Mainstream Pharmacology Is Long Overdue
2007
·
Dennis A. Smith
, Maurice Dickins
, et al.
·
Drug Metabolism and Disposition
·
21
Effect of moxidectin on CYP3A4 activity as evaluated by oral midazolam pharmacokinetics in healthy subjects
2013
·
Joan M. Korth‐Bradley
, Virginia Parks
, et al.
·
Clinical Pharmacology in Drug Development
·
20
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Works count:
35
Citation count:
1,776
H-index:
22
I10-index:
28
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