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Takushi Shimomura
Observed names:
SHIMOMURA, TAKUSHI,
Shimomura, Takushi,
T. Shimomura,
Takushi SHIMOMURA
Institutions:
Hiroshima University,
The Graduate University for Advanced Studies, SOKENDAI,
National Institute for Physiological Sciences
Observed institutions:
Hiroshima University,
The Graduate University for Advanced Studies, SOKENDAI,
Kyoto University,
National Institute for Physiological Sciences,
Cellular and Structural Physiology Institute, Nagoya University,
Nagoya University
show all 6
ORCID:
0000-0002-8109-535X
Observed ORCID:
0000-0002-8109-535X
OpenAlex ID:
A5020306754
Works
63
Awards
4
RETRACTED ARTICLE: Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression
2019
·
Atsunori Kamiya
, Yohsuke Hayama
, et al.
·
Nature Neuroscience
·
292
Control of Spontaneous Ca2+Transients Is Critical for Neuronal Maturation in the Developing Neocortex
2014
·
Yuki Bando
, Katsumasa Irie
, et al.
·
Cerebral Cortex
·
76
Comparative Study of the Gating Motif and C-type Inactivation in Prokaryotic Voltage-gated Sodium Channels
2009
·
Katsumasa Irie
, Kazuya Kitagawa
, et al.
·
Journal of Biological Chemistry
·
65
Two Alternative Conformations of a Voltage-Gated Sodium Channel
2013
·
Ching-Ju Tsai
, Kazutoshi Tani
, et al.
·
Journal of Molecular Biology
·
58
PDF
A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence
2020
·
Takushi Shimomura
, Yoshiki Yonekawa
, et al.
·
eLife
·
34
Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior
2022
·
Daisuke Tsuboi
, Takeshi Otsuka
, et al.
·
Cell Reports
·
29
PDF
The C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rate
2012
·
Katsumasa Irie
, Takushi Shimomura
, et al.
·
Nature Communications
·
29
PDF
Phosphoinositides modulate the voltage dependence of two-pore channel 3
2019
·
Takushi Shimomura
, Yoshihiro Kubo
·
The Journal of General Physiology
·
19
Optimized expression and purification of NavAb provide the structural insight into the voltage dependence
2017
·
Katsumasa Irie
, Yukari Haga
, et al.
·
FEBS Letters
·
16
PDF
SLO potassium channels antagonize premature decision making in C. elegans
2018
·
Ichiro Aoki
, Michihiro Tateyama
, et al.
·
Communications Biology
·
15
PDF
Two mutations at different positions in the CNBH domain of the hERG channel accelerate deactivation and impair the interaction with the EAG domain
2018
·
Shinichiro Kume
, Takushi Shimomura
, et al.
·
The Journal of Physiology
·
15
Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization
2021
·
Kazuki Matsumura
, Takushi Shimomura
, et al.
·
BMC Molecular and Cell Biology
·
14
PDF
Arrangement and Mobility of the Voltage Sensor Domain in Prokaryotic Voltage-gated Sodium Channels
2010
·
Takushi Shimomura
, Katsumasa Irie
, et al.
·
Journal of Biological Chemistry
·
13
PDF
Conformational rearrangements in the second voltage sensor domain switch PIP 2 - and voltage-gating modes in two-pore channels
2023
·
Takushi Shimomura
, Kiichi Hirazawa
, et al.
·
Proceedings of the National Academy of Sciences
·
9
Phosphoinositide regulates dynamic movement of the S4 voltage sensor in the second repeat in two-pore channel 3
2021
·
Kiichi Hirazawa
, Michihiro Tateyama
, et al.
·
Journal of Biological Chemistry
·
6
Closed-state inactivation of cardiac, skeletal, and neuronal sodium channels is isoform specific
2022
·
Niklas Brake
, Adamo S. Mancino
, et al.
·
The Journal of General Physiology
·
5
Molecular determinants of prokaryotic voltage‐gated sodium channels for recognition of local anesthetics
2016
·
Takushi Shimomura
, Katsumasa Irie
, et al.
·
FEBS Journal
·
5
Evidence for lateral mobility of voltage sensors in prokaryotic voltage-gated sodium channels
2010
·
Hitoshi Nagura
, Katsumasa Irie
, et al.
·
Biochemical and Biophysical Research Communications
·
5
Characterization and Engineering of a Blue-Sensitive, Gi/o-Biased, and Bistable Ciliary Opsin from a Fan Worm
2025
·
Sachiko Fukuzawa
, Tomoki Kawaguchi
, et al.
·
Biochemistry
·
3
Retraction Note: Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression
2024
·
Atsunori Kamiya
, Yohsuke Hayama
, et al.
·
Nature Neuroscience
·
3
PDF
Intrinsic Gating Behavior of Voltage-Gated Sodium Channels Predetermines Regulation by Auxiliary β-subunits
2021
·
Niklas Brake
, Adamo S Mancino
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
3
PDF
Extracellular K+ modulates the pore conformations of Cys-loop receptor anion channels
2026
·
Takushi Shimomura
, Yoshihiro Kubo
, et al.
·
Nature Communications
·
1
PDF
Functional characterization of zebrafish Kcnh2a splice variants reveals distinct gating properties
2026
·
Shinichiro Kume
, Takushi Shimomura
, et al.
·
Biochemical and Biophysical Research Communications
Extracellular K+ modulates the pore conformations of Cys-loop receptor anion channels
2026
·
SHIMOMURA, TAKUSHI
, Kubo, Yoshihiro
, et al.
·
Figshare
Descending to inhibit: Antagonist-induced downward shift of VSD II in TPC2
2024
·
Takushi Shimomura
·
Structure
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Works count:
63
Citation count:
716
H-index:
13
I10-index:
13
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