Author

Jennings F. Worley

Observed names: J F Worley, J. F. Worley, J. WORLEY, J. Worley, J.F. Worley, JENNINGS F. WORLEY, Jennings F Worley, III, Jennings F. Worley III, Jennings F. Worley, III, Jennings Worley, Jennings Worley, III

Institution: Vertex Pharmaceuticals (United States)

Observed institutions: University of Vermont, West Virginia University, University of Maryland, Baltimore, University of Miami, GlaxoSmithKline (United Kingdom), University of Chicago, GlaxoSmithKline (United States), Heinrich Heine University Düsseldorf, Vertex Pharmaceuticals (United States), University of Pennsylvania

OpenAlex ID: A5020816632

Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone

1990 · M. T. Nelson, J. B. Patlak, et al. · American Journal of Physiology-Cell Physiology · 1,096

Ivacaftor potentiation of multiple CFTR channels with gating mutations

2012 · Haihui Yu, Bill Burton, et al. · Journal of Cystic Fibrosis · 423

PDF

Noradrenaline contracts arteries by activating voltage-dependent calcium channels

1988 · Mark T. Nelson, Nicholas B. Standen, et al. · Nature · 333

IonWorks™ HT: A New High-Throughput Electrophysiology Measurement Platform

2003 · Kirk Schroeder, Brad Neagle, et al. · SLAS DISCOVERY · 220

PDF

Single sodium channels from rat brain incorporated into planar lipid bilayer membranes

1983 · Bruce K. Krueger, Jennings F. Worley, et al. · Nature · 181

Endoplasmic reticulum calcium store regulates membrane potential in mouse islet beta-cells.

1994 · J.F. Worley, M.S. McIntyre, et al. · Journal of Biological Chemistry · 157

PDF

Defective glucose-dependent endoplasmic reticulum Ca2+ sequestration in diabetic mouse islets of Langerhans

1994 · M.W. Roe, L.H. Philipson, et al. · Journal of Biological Chemistry · 147

PDF

Dependence on NADH produced during glycolysis for beta-cell glucose signaling

1994 · I.D. Dukes, M.S. McIntyre, et al. · Journal of Biological Chemistry · 138

Expression and Function of Pancreatic β-Cell Delayed Rectifier K+ Channels

1996 · Michael Wm. Roe, Jennings F. Worley, et al. · Journal of Biological Chemistry · 120

Characterization of a Ca2+ Release-activated Nonselective Cation Current Regulating Membrane Potential and [Ca2+] Oscillations in Transgenically Derived β-Cells

1998 · Michael W. Roe, Jennings F. Worley, et al. · Journal of Biological Chemistry · 111

Depletion of intracellular Ca2+ stores activates a maitotoxin-sensitive nonselective cationic current in beta-cells.

1994 · J F Worley, M S McIntyre, et al. · Journal of Biological Chemistry · 109

Voltage-dependent intracellular calcium release from mouse islets stimulated by glucose

1993 · M.W. Roe, M.E. Lancaster, et al. · Journal of Biological Chemistry · 108

Activation of Stimulus-Secretion Coupling in Pancreatic β-Cells by Specific Products of Glucose Metabolism

1996 · Robert J. Mertz, Jennings F. Worley, et al. · Journal of Biological Chemistry · 104

PDF

Single nisoldipine-sensitive calcium channels in smooth muscle cells isolated from rabbit mesenteric artery.

1986 · J F Worley, J W Deitmer, et al. · Proceedings of the National Academy of Sciences · 104

HTS approaches to voltage-gated ion channel drug discovery

1998 · Jane Denyer, Jennings Worley, et al. · Drug Discovery Today · 100

Dihydropyridine inhibition of single calcium channels and contraction in rabbit mesenteric artery depends on voltage.

1989 · M T Nelson, J F Worley · The Journal of Physiology · 87

Voltage-dependent block by saxitoxin of sodium channels incorporated into planar lipid bilayers

1984 · R.J. French, J.F. Worley, et al. · Biophysical Journal · 85

PDF

Trimethyloxonium modification of single batrachotoxin-activated sodium channels in planar bilayers. Changes in unit conductance and in block by saxitoxin and calcium.

1986 · J F Worley, R J French, et al. · The Journal of General Physiology · 78

Thapsigargin inhibits the glucose-induced decrease of intracellular Ca2+ in mouse islets of Langerhans

1994 · M. W. Roe, R. J. Mertz, et al. · American Journal of Physiology-Endocrinology and Metabolism · 77

Inhibition of human breast cancer cell proliferation in tissue culture by the neuroleptic agents pimozide and thioridazine.

1990 · J S Strobl, K L Kirkwood, et al. · PubMed · 75

Dihydropyridine-sensitive single calcium channels in airway smooth muscle cells

1990 · J. F. Worley, M. I. Kotlikoff · American Journal of Physiology-Lung Cellular and Molecular Physiology · 73

Regulation of single calcium channels in cerebral arteries by voltage, serotonin, and dihydropyridines

1991 · J. F. Worley, J. M. Quayle, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 65

Delayed rectifier K+ channel overexpression in transgenic islets and beta-cells associated with impaired glucose responsiveness.

1994 · L H Philipson, M P Rosenberg, et al. · Journal of Biological Chemistry · 64

Amylin modulates beta-cell glucose sensing via effects on stimulus-secretion coupling.

1993 · P K Wagoner, C Chen, et al. · Proceedings of the National Academy of Sciences · 62

PDF

NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity

1996 · M. W. Roe, J. F. Worley, et al. · American Journal of Physiology-Endocrinology and Metabolism · 48

Works count: 50

Citation count: 4,523

H-index: 30

I10-index: 36