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J. Agustin Cruz

Observed names: J Agustin Cruz, J. Agustin Cruz
ORCID: 0000-0002-4927-9140
Observed ORCID: 0000-0002-4927-9140
OpenAlex ID: A5021722010
IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis
2016 · Heather R. Conti, Vincent M. Bruno, et al. · Cell Host & Microbe · 177
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MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation
2015 · Abhishek V. Garg, Nilesh Amatya, et al. · Immunity · 145
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IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a
2018 · Nilesh Amatya, Erin E. Childs, et al. · Science Signaling · 75
CCAAT/Enhancer-binding protein β promotes pathogenesis of EAE
2017 · Michelle R. Simpson-Abelson, Gerard Hernandez-Mir, et al. · Cytokine · 45
Sex-, stress-, and sympathetic post-ganglionic-dependent changes in identity and proportions of immune cells in the dura
2016 · Lisa A McIlvried, J Agustin Cruz, et al. · Cephalalgia · 39
Chronic hypoxia induces right heart failure in caveolin-1−/− mice
2012 · J. Agustin Cruz, Eileen M. Bauer, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 37
A network-centric approach to drugging TNF-induced NF-κB signaling
2019 · Nicolas A. Pabon, Qiuhong Zhang, et al. · Nature Communications · 34
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IL-17 Signaling Triggers Degradation of the Constitutive NF-κB Inhibitor ABIN-1
2017 · J Agustin Cruz, Erin E Childs, et al. · ImmunoHorizons · 29
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A variable-gain stochastic pooling motif mediates information transfer from receptor assemblies into NF-κB
2021 · J. Agustin Cruz, Chaitanya S. Mokashi, et al. · Science Advances · 20
dNEMO: a tool for quantification of mRNA and punctate structures in time-lapse images of single cells
2020 · Gabriel J Kowalczyk, J Agustin Cruz, et al. · Bioinformatics · 8
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Stochastic pooling of IKK/NEMO complexes describes information transmission in the NF-KB pathway in response to IL-1 and TNF stimulation
2021 · J Agustin Cruz, Chaitanya Mokashi, et al. · The Journal of Immunology · 1
Arid5a orchestrates IL-17-mediated inflammation through post-transcriptional control of mRNA
2018 · Nilesh Amatya, J Agustin Cruz, et al. · The Journal of Immunology · 1
Decoding Treg diversity and dysfunction to advance Treg-based therapies in autoimmune and inflammatory diseases
2026 · Austin McKay, J. Agustin Cruz, et al. · Frontiers in Immunology
Decoding patterns of macrophage TNF production to model NF-κB dynamics and cell-cell communication
2020 · J. Agustin Cruz, Rachel A. Gottschalk, et al. · The Journal of Immunology
Functional Regulation of Interleukin-17 Receptor Signaling
2018 · J. Agustin Cruz · D-Scholarship@Pitt (University of Pittsburgh)
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Faculty Opinions recommendation of IL-17 sequestration via salivary gland gene therapy in a mouse model of Sjogren's syndrome suppresses disease-associated expression of the putative autoantigen Klk1b22.
2015 · Sarah Gaffen, J Agustin Cruz · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
ID: 36
2015 · Abhishek Garg, Nilesh Amatya, et al. · Cytokine
ID: 179
2015 · J. Agustin Cruz, Abhishek V. Garg, et al. · Cytokine
Faculty Opinions recommendation of IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations.
2015 · Sarah Gaffen, J Agustin Cruz · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Faculty Opinions recommendation of T(H)17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26.
2015 · Sarah Gaffen, J Agustin Cruz · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Faculty Opinions recommendation of Syk mediates IL-17-induced CCL20 expression by targeting Act1-dependent K63-linked ubiquitination of TRAF6.
2015 · Sarah Gaffen, J Agustin Cruz · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Faculty Opinions recommendation of Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity.
2015 · Sarah Gaffen, J Agustin Cruz · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Faculty Opinions recommendation of TNIP1 reduction of HSPA6 gene expression occurs in promoter regions lacking binding sites for known TNIP1-repressed transcription factors.
2015 · Sarah Gaffen, J Agustin Cruz · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Faculty Opinions recommendation of Emergence of the A20/ABIN-mediated inhibition of NF-κB signaling via modifying the ubiquitinated proteins in a basal chordate.
2014 · Sarah Gaffen, J Agustin Cruz · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Faculty Opinions recommendation of Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.
2014 · Sarah Gaffen, J Agustin Cruz · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Works count: 27
Citation count: 611
H-index: 9
I10-index: 9
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