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Gladys N. Macharia
Observed names:
Gladys Macharia,
Gladys N Macharia,
Macharia, Gladys Njeri
Institution:
Imperial College London
Observed institutions:
International AIDS Vaccine Initiative,
Kenya Medical Research Institute,
KEMRI-Wellcome Trust Research Programme,
Imperial College London
ORCID:
0000-0002-5605-5604
Observed ORCID:
0000-0002-5605-5604
OpenAlex ID:
A5022561453
Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4 + T cells, and disease progression
2015
·
Daniel T. Claiborne
, Jessica L. Prince
, et al.
·
Proceedings of the National Academy of Sciences
·
102
Control of Viremia Enables Acquisition of Resting Memory B Cells with Age and Normalization of Activated B Cell Phenotypes in HIV-Infected Children
2015
·
Daniel M Muema
, Gladys N Macharia
, et al.
·
The Journal of Immunology
·
31
Proportions of circulating follicular helper T cells are reduced and correlate with memory B cells in HIV-infected children
2017
·
Daniel M. Muema
, Gladys N. Macharia
, et al.
·
PLoS ONE
·
16
PDF
Infection with multiple HIV-1 founder variants is associated with lower viral replicative capacity, faster CD4+ T cell decline and increased immune activation during acute infection
2020
·
Gladys N. Macharia
, Ling Yue
, et al.
·
PLoS Pathogens
·
15
PDF
Better Viral Control despite Higher CD4 + T Cell Activation during Acute HIV-1 Infection in Zambian Women Is Linked to the Sex Hormone Estradiol
2020
·
Elina El-Badry
, Gladys Macharia
, et al.
·
Journal of Virology
·
15
Utilizing Computational Machine Learning Tools to Understand Immunogenic Breadth in the Context of a CD8 T-Cell Mediated HIV Response
2021
·
Ed McGowan
, Rachel Rosenthal
, et al.
·
Frontiers in Immunology
·
10
PDF
Breadth of CD8 T-cell mediated inhibition of replication of diverse HIV-1 transmitted-founder isolates correlates with the breadth of recognition within a comprehensive HIV-1 Gag, Nef, Env and Pol potential T-cell epitope (PTE) peptide set
2021
·
Peter Hayes
, Natalia Fernandez
, et al.
·
PLoS ONE
·
9
PDF
Direct identification of HLA‐presented CD8 T cell epitopes from transmitted founder HIV‐1 variants
2021
·
Jonathan Hare
, Gladys Macharia
, et al.
·
PROTEOMICS
·
9
PDF
Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis
2019
·
Daniel T. Claiborne
, Eileen P. Scully
, et al.
·
PLoS Pathogens
·
9
PDF
Infection with HIV-1 subtype D among acutely infected Ugandans is associated with higher median concentration of cytokines compared to subtype A
2022
·
Anne Kapaata
, Sheila N. Balinda
, et al.
·
IJID Regions
·
6
PDF
A Novel Sample Selection Approach to Aid the Identification of Factors That Correlate With the Control of HIV-1 Infection
2021
·
Julia Makinde
, Eunice W. Nduati
, et al.
·
Frontiers in Immunology
·
4
PDF
Transmission of Multiple HIV-1 Founder Viruses and High Frequency of Unique Recombinant Forms among MSM in Kenya
2016
·
Gladys Macharia
, Lifan Yue
, et al.
·
AIDS Research and Human Retroviruses
·
1
HIV Replicative Capacity of Transmitted Viruses Is Associated with Early Immune Activation, Exhaustion and Establishment of the Viral Reservoir
2014
·
Jessica L. Prince
, Daniel T. Claiborne
, et al.
·
AIDS Research and Human Retroviruses
·
1
The role of HIV-1 transmitted/founder virus characteristics in driving pathogenesis
2019
·
Macharia, Gladys Njeri
·
Spiral (Imperial College London)
PDF
Infection With Multiple Transmitted/Founder (TF) HIV-1 Viruses Impacts Peak VL and HIV-1 Pathogenesis
2018
·
Gladys Macharia
, Ecco Staller
, et al.
·
AIDS Research and Human Retroviruses
Protective HLA Alleles Reduce Markers of Gut Damage and Microbial Translocation and Preserve the Cellular Immune Response during Acute HIV-1 Infection
2014
·
Daniel Claiborne
, Jessica Prince
, et al.
·
AIDS Research and Human Retroviruses
African Early Infection Cohort as a Platform for Vaccine Discovery: The IAVI Protocol C Experience
2014
·
Jill Gilmour
, Anatoli Kamali
, et al.
·
AIDS Research and Human Retroviruses
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Works count:
17
Citation count:
228
H-index:
9
I10-index:
6
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