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Charles J. R. Hedgecock

Observed names: C HEDGECOCK, C. J. R. HEDGECOCK, C.J.R. Hedgecock, Charles Hedgecock, Charles J. R. HEDGECOCK, Charles J.R Hedgecock, Charles J.R. Hedgecock, Charles JR Hedgecock
Institution: Uppsala University
OpenAlex ID: A5024110321
Synthesis, Structure−Activity Relationships, and Pharmacokinetic Properties of Dihydroorotate Dehydrogenase Inhibitors: 2-Cyano-3-cyclopropyl-3-hydroxy- N-[3‘-methyl-4‘-(trifluoromethyl)phenyl]propenamide and Related Compounds
1996 · Elizabeth A. Kuo, Philip T. Hambleton, et al. · Journal of Medicinal Chemistry · 91
The rapidly expanding range of neuronal benzodiazepine receptor ligands
1993 · C GARDNER, W TULLY, et al. · Progress in Neurobiology · 84
A novel application of the Dess-Martin reagent to the synthesis of an FK506 analogue and other tricarbonyl compounds
1993 · Mark J. Batchelor, Roger J. Gillespie, et al. · Tetrahedron Letters · 62
The interleukin-2 and interleukin-4 receptors studied by molecular modelling
1994 · Paul Bamborough, Charles JR Hedgecock, et al. · Structure · 57
Asymmetric Synthesis of (-)-Tetrahydrolipstatin
1991 · Stephen C. Case-Green, Stephen G. Davies, et al. · Synlett · 55
Asymmetric Synthesis of Homochiral β-Lactones via the Iron Chiral Auxiliary [(η5-C5H5)Fe(CO)(PPh3)]
1991 · Stephen C. Case-Green, Stephen G. Davies, et al. · Synlett · 30
A stereocontrolled approach to 1β-methylcarbapenem
1995 · Stephen G. Davies, Charles J.R. Hedgecock, et al. · Tetrahedron Asymmetry · 28
A direct method for the alkylation of adenosine nucleosides at position 8.
1979 · Derek H.R. Barton, Charles J.R. Hedgecock, et al. · Tetrahedron Letters · 26
Stereochemistry of the reductoisomerase and αβ-dihydroxyacid dehydratase-catalysed steps in valine and isoleucine biosynthesis. Observation of a novel tertiary ketol rearrangement
1974 · Frank B. Armstrong, Charles J. R. Hedgecock, et al. · Journal of the Chemical Society Chemical Communications · 25
Asymmetric Synthesis of (2S,3S)- and (2R,3S)-2,3-Diaminobutanoic Acids, Non-Protein Amino-Acid Diastereomers found in a number of Peptide Antibiotics
1996 · Anthony J. Burke, Stephen G. Davies, et al. · Synlett · 24
A computer model of the interleukin‐4/receptor complex
1993 · Paul Bamborough, Guy H. Grant, et al. · Proteins Structure Function and Bioinformatics · 23
Analysis of immunoreceptor tyrosine‐based activation motif (ITAM) binding to ZAP‐70 by surface plasmon resonance
1997 · Frédéric Vély, Jacques A. Nunès, et al. · European Journal of Immunology · 22
A formal total asymmetric synthesis of (+)-thienamycin
1995 · Stephen G Davies, Charles J.R Hedgecock, et al. · Tetrahedron Asymmetry · 22
Total syntheses of close analogues of the immunosuppressant FK506
1994 · Mark J Batchelor, Roger J Gillespie, et al. · Tetrahedron · 21
The base-catalysed rearrangement of α-acetolactate (2-hydroxy-2-methyl-3-oxobutanoate) : a novel carboxylate ion migration in a tertiary ketol rearrangement
1979 · David H. G. Crout, Charles J. R. Hedgecock · Journal of the Chemical Society Perkin Transactions 1 · 21
Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase
2018 · Natalia Szałaj, Lu Lu, et al. · European Journal of Medicinal Chemistry · 19
Drug targets in inflammation and immunomodulation
1997 · Derek R. Buckle, Charles J.R. Hedgecock · Drug Discovery Today · 14
Kinetic resolution of the chiral iron acetyl complexes [Fe(CO)(η 5 -C 5 H 5 )(L)COCH 3 ][L = PPh 3 , P(p-tolyl) 3 ]via aldol reactions with camphor
1994 · Stephen C. Case-Green, James F. Costello, et al. · Journal of the Chemical Society Perkin Transactions 1 · 12
A new approach to phospholipase A2 inhibition
1992 · Julian M.C. Golec, Charles J.R. Hedgecock, et al. · Tetrahedron Letters · 10
New Synthetic S-Adenosylhomocysteine Analogues with Oncostatic and Antiviral Activity
1978 · Edgar Lederer, Marc Vuilhorgne, et al. · Heterocycles · 9
Stereochemistry of Valine Biosynthesis
1980 · David H. G. CROUT, Charles J. R. HEDGECOCK, et al. · European Journal of Biochemistry · 7
Kinetic resolution of the chiral iron acetyl [Fe(η 5 -C 5 H 5 )(CO)(PPh 3 )COMe]
1993 · Stephen C. Case-Green, James F. Costello, et al. · Journal of the Chemical Society Chemical Communications · 6
A versatile synthon approach to the preparation of some phospholipase A2 inhibitors
1992 · JMC Golec, C.J.R. Hedgecock, et al. · Tetrahedron Letters · 5
Biosynthesis of L-valine in Salmonella typhimurium: origin of the diastereotopic methyl groups
1980 · David H. G. Crout, Charles J. R. Hedgecock, et al. · Journal of the Chemical Society Chemical Communications · 4
ChemInform Abstract: Asymmetric Synthesis of (2S,3S)‐ and (2R,3S)‐2,3‐Diaminobutanoic Acids, Non‐Protein Amino‐Acid Diastereomers Found in a Number of Peptide Antibiotics.
1996 · A. J. BURKE, S. G. DAVIES, et al. · ChemInform · 1
Works count: 33
Citation count: 679
H-index: 16
I10-index: 19
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