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Karen L. Marquis

Observed names: K L Marquis, K. L. MARQUIS, K. L. Marquis, K. Marquis, K.L. Marquis, Karen L Marquis, Karen Marquis
OpenAlex ID: A5028117769
Activation of estrogen receptor-β regulates hippocampal synaptic plasticity and improves memory
2008 · Feng Liu, Mark Day, et al. · Nature Neuroscience · 504
Phosphodiesterase 10A Inhibitor Activity in Preclinical Models of the Positive, Cognitive, and Negative Symptoms of Schizophrenia
2009 · Steven M. Grauer, Virginia L. Pulito, et al. · Journal of Pharmacology and Experimental Therapeutics · 270
Schizophrenia-Related Neural and Behavioral Phenotypes in Transgenic Mice Expressing TruncatedDisc1
2008 · Sanbing Shen, Bing Lang, et al. · Journal of Neuroscience · 250
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Acute γ-Secretase Inhibition Improves Contextual Fear Conditioning in the Tg2576 Mouse Model of Alzheimer's Disease
2005 · Thomas A. Comery, Robert L. Martone, et al. · Journal of Neuroscience · 214
ADX47273 [S-(4-Fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: A Novel Metabotropic Glutamate Receptor 5-Selective Positive Allosteric Modulator with Preclinical Antipsychotic-Like and Procognitive Activities
2008 · Feng Liu, Steve Grauer, et al. · Journal of Pharmacology and Experimental Therapeutics · 183
Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist
2009 · Robert H. Ring, Lee E. Schechter, et al. · Neuropharmacology · 145
WAY-163909 [(7 bR,10 aR)-1,2,3,4,8,9,10,10 a-Octahydro-7 bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole]: A Novel 5-Hydroxytryptamine 2C Receptor-Selective Agonist with Preclinical Antipsychotic-Like Activity
2006 · Karen L. Marquis, Annmarie L. Sabb, et al. · Journal of Pharmacology and Experimental Therapeutics · 144
Lecozotan (SRA-333): A Selective Serotonin 1A Receptor Antagonist That Enhances the Stimulated Release of Glutamate and Acetylcholine in the Hippocampus and Possesses Cognitive-Enhancing Properties
2005 · L.E. Schechter, D.L. Smith, et al. · Journal of Pharmacology and Experimental Therapeutics · 129
Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents
2007 · Sharon Rosenzweig-Lipson, Annmarie Sabb, et al. · Psychopharmacology · 102
Pharmacological comparison of muscarinic ligands: Historical versus more recent muscarinic M1-preferring receptor agonists
2009 · Julia N. Heinrich, John A. Butera, et al. · European Journal of Pharmacology · 101
The orphan GPCR, GPR88, modulates function of the striatal dopamine system: A possible therapeutic target for psychiatric disorders?
2009 · Sheree F. Logue, Steven M. Grauer, et al. · Molecular and Cellular Neuroscience · 91
Synthesis and SAR of Adatanserin: Novel Adamantyl Aryl- and Heteroarylpiperazines with Dual Serotonin 5-HT1A and 5-HT2 Activity as Potential Anxiolytic and Antidepressant Agents
1999 · Magid A. Abou-Gharbia, Wayne E. Childers, et al. · Journal of Medicinal Chemistry · 82
Pharmacological Profile of the 5‐HT2C Receptor Agonist WAY‐163909; Therapeutic Potential in Multiple Indications
2006 · John Dunlop, Karen L. Marquis, et al. · CNS Drug Reviews · 79
Highly Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitors
2011 · Michael S. Malamas, Yike Ni, et al. · Journal of Medicinal Chemistry · 71
Discovery of Imidazo[1,5-a]pyrido[3,2-e]pyrazines as a New Class of Phosphodiesterase 10A Inhibitiors
2010 · Norbert Höfgen, Hans Stange, et al. · Journal of Medicinal Chemistry · 63
Discovery of N1-(6-Chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a Potent, Selective, and Orally Active 5-HT6Receptor Agonist
2007 · Derek C. Cole, Joseph R. Stock, et al. · Journal of Medicinal Chemistry · 61
Estrogen Receptor Neurobiology and its Potential for Translation into Broad Spectrum Therapeutics for CNS Disorders
2009 · Zoe Hughes, Feng Liu, et al. · Current Molecular Pharmacology · 59
Comparative electroencephalographic and behavioral effects of phencyclidine, (+)-SKF-10,047 and MK-801 in rats.
1989 · K L Marquis, N C Paquette, et al. · Journal of Pharmacology and Experimental Therapeutics · 47
5-HT2C Receptor Agonists as an Innovative Approach for Psychiatric Disorders
2007 · Sharon Rosenzweig-Lipson, John Dunlop, et al. · Drug News & Perspectives · 46
New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D2Agonist Pharmacophore. Structure−Activity Relationships of a Series of 2-(Aminomethyl)chromans
1997 · Richard E. Mewshaw, Joseph Kavanagh, et al. · Journal of Medicinal Chemistry · 43
5-HT2C Agonists as Therapeutics for the Treatment of Schizophrenia
2012 · Sharon Rosenzweig-Lipson, Thomas A. Comery, et al. · Handbook of experimental pharmacology · 42
The inhibition of glycogen synthase kinase 3β by a metabotropic glutamate receptor 5 mediated pathway confers neuroprotection to Aβ peptides
2005 · Feng Liu, Xiaohai Gong, et al. · Journal of Neurochemistry · 42
Effects of fixed ratio size and dose on phencyclidine self-administration by rats
1989 · Karen L. Marquis, Michael G. Webb, et al. · Psychopharmacology · 42
The convulsant and anticonvulsant effects of phencyclidine (PCP) and PCP analogues in the rat
1986 · Arthur P. Leccese, Karen L. Marquis, et al. · Behavioural Brain Research · 40
Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonists Containing a Urea Moiety: Identification and Characterization of the Potent, Selective, and Orally Efficacious Agonist 1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) Urea (SEN34625/WYE-103914)
2010 · Chiara Ghiron, Simon N. Haydar, et al. · Journal of Medicinal Chemistry · 30
Works count: 65
Citation count: 3,311
H-index: 28
I10-index: 46
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