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Sebastian J. Pomplun

Observed names: Pomplun, Sebastian, S. Pomplun, Sebastian Pomplun
ORCID: 0000-0003-0905-8551
Observed ORCID: 0000-0003-0905-8551
OpenAlex ID: A5028126343
Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD
2020 · G. Zhang, S. Pomplun, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 153
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De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV‑2 Spike Protein
2020 · Sebastian Pomplun, Muhammad Jbara, et al. · ACS Central Science · 88
Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins
2018 · Sebastian Pomplun, Claudia Sippel, et al. · Journal of Medicinal Chemistry · 62
Engineering Bioactive Dimeric Transcription Factor Analogs via Palladium Rebound Reagents
2021 · Muhammad Jbara, Sebastian Pomplun, et al. · Journal of the American Chemical Society · 51
Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides
2020 · Sebastian Pomplun · RSC Medicinal Chemistry · 49
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Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides
2021 · Jürgen M. Kolos, Sebastian Pomplun, et al. · Chemical Science · 41
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Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription
2021 · Sebastian Pomplun, Muhammad Jbara, et al. · ACS Central Science · 35
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Rational Design and Asymmetric Synthesis of Potent and Neurotrophic Ligands for FK506‐Binding Proteins (FKBPs)
2014 · Sebastian Pomplun, Yansong Wang, et al. · Angewandte Chemie International Edition · 33
Discovery of Nucleic Acid Binding Molecules from Combinatorial Biohybrid Nucleobase Peptide Libraries
2020 · Sebastian Pomplun, Zachary P. Gates, et al. · Journal of the American Chemical Society · 31
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Efficient Pictet–Spengler Bioconjugation with N ‐Substituted Pyrrolyl Alanine Derivatives
2019 · Sebastian Pomplun, Mohamed Y. H. Mohamed, et al. · Angewandte Chemie International Edition · 29
Advances in Ultrahigh Throughput Hit Discovery with Tandem Mass Spectrometry Encoded Libraries
2023 · J. Miguel Mata, Edith van der Nol, et al. · Journal of the American Chemical Society · 26
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Loratadine and Analogues: Discovery and Preliminary Structure–Activity Relationship of Inhibitors of the Amino Acid Transporter B0AT2
2014 · Serena Cuboni, Christian Devigny, et al. · Journal of Medicinal Chemistry · 26
Recent Progress in FKBP Ligand Development
2015 · Xixi Feng, Sebastian Pomplun, et al. · Current Molecular Pharmacology · 22
Secondary Amino Alcohols: Traceless Cleavable Linkers for Use in Affinity Capture and Release
2020 · Sebastian Pomplun, Christopher R. Shugrue, et al. · Angewandte Chemie International Edition · 18
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Evaluating BindCraft for Generative Design of High-Affinity Peptides
2025 · Mike Filius, Thanasis Patsos, et al. · ACS Chemical Biology · 16
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Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC
2024 · Brecht D. Ellenbroek, Jan Pascal Kahler, et al. · Angewandte Chemie International Edition · 12
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Automated Flow Peptide Synthesis Enables Engineering of Proteins with Stabilized Transient Binding Pockets
2024 · Anna Charalampidou, Thomas Nehls, et al. · ACS Central Science · 12
Synthetic Peptides: Promising Modalities for the Targeting of Disease‐Related Nucleic Acids
2024 · Brecht D. Ellenbroek, Jan Pascal Kahler, et al. · Angewandte Chemie International Edition · 11
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Rationales Design und asymmetrische Synthese potenter neuritotropher Liganden für FK506‐bindende Proteine (FKBPs)
2014 · Sebastian Pomplun, Yansong Wang, et al. · Angewandte Chemie · 7
Barcode-free hit discovery from massive libraries enabled by automated small molecule structure annotation
2025 · Edith van der Nol, Nils Alexander Haupt, et al. · Nature Communications · 6
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Efficient Pictet–Spengler Bioconjugation with N‐Substituted Pyrrolyl Alanine Derivatives
2019 · Sebastian Pomplun, Mohamed Y. H. Mohamed, et al. · Angewandte Chemie · 6
Generative Design of High-Affinity Peptides Using BindCraft
2025 · Mike Filius, Thanasis Patsos, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
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Massive barcode-free chemical screenings enable the discovery of bioactive macrocycles with passive membrane permeability
2026 · J. Miguel Mata, Jingming Liu, et al. · Nature Communications · 3
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Use of DNA forceps to measure receptor-ligand dissociation equilibrium constants in a single-molecule competition assay
2024 · François Stransky, Dorota Kostrz, et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 3
Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides
2021 · Sebastian Pomplun · DSpace@MIT (Massachusetts Institute of Technology) · 3
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Works count: 48
Citation count: 752
H-index: 15
I10-index: 18
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