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Simeng Xu
Institution:
Northwest A&F University
Observed institutions:
Hunan Normal University,
Yantai University,
Beijing University of Chemical Technology,
Northwest A&F University
ORCID:
0000-0002-1697-8391
Observed ORCID:
0000-0002-1697-8391
OpenAlex ID:
A5028409253
Down‐regulation of PKM2 decreases FASN expression in bladder cancer cells through AKT/mTOR/SREBP‐1c axis
2018
·
Ting Tao
, Qiongli Su
, et al.
·
Journal of Cellular Physiology
·
96
Metformin targets Clusterin to control lipogenesis and inhibit the growth of bladder cancer cells through SREBP-1c/FASN axis
2021
·
Jun Deng
, Mei Peng
, et al.
·
Signal Transduction and Targeted Therapy
·
61
PDF
Reduction-sensitive platinum (IV)-prodrug nano-sensitizer with an ultra-high drug loading for efficient chemo-radiotherapy of Pt-resistant cervical cancer in vivo
2020
·
Kejun Luo
, Wenxuan Guo
, et al.
·
Journal of Controlled Release
·
56
Inhibition of PKM2 Enhances Sensitivity of Olaparib to Ovarian Cancer Cells and Induces DNA Damage
2022
·
Sichun Zhou
, Duo Li
, et al.
·
International Journal of Biological Sciences
·
47
Vitamin A prevents lipopolysaccharide‐induced injury on tight junctions in mice
2020
·
Caimei He
, Xin Hu
, et al.
·
Food Science & Nutrition
·
24
PDF
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy
2022
·
Di Xiao
, Xin Hu
, et al.
·
Cell Death and Disease
·
21
PDF
4-Methoxydalbergione Inhibits Bladder Cancer Cell Growth via Inducing Autophagy and Inhibiting Akt/ERK Signaling Pathway
2022
·
Haifang Du
, Ting Tao
, et al.
·
Frontiers in Molecular Biosciences
·
21
Anticancer properties of novel pyrazole‐containing biguanide derivatives with activating the adenosine monophosphate‐activated protein kinase signaling pathway
2019
·
Sichun Zhou
, Leichuan Xu
, et al.
·
Archiv der Pharmazie
·
17
Synthesis, biological evaluation and anti-proliferative mechanism of fluorine-containing proguanil derivatives
2019
·
Di Xiao
, Zhicheng Lu
, et al.
·
Bioorganic & Medicinal Chemistry
·
16
Synthesis, Anti-Proliferative Evaluation and Mechanism of 4-Trifluoro Methoxy Proguanil Derivatives with Various Carbon Chain Length
2021
·
Simeng Xu
, Yufang Cao
, et al.
·
Molecules
·
10
PDF
Simultaneous quantification of baloxavir marboxil and its active metabolite in human plasma using UHPLC-MS/MS: Application to a human pharmacokinetic study with different anticoagulants
2024
·
Haiyan Liu
, Simeng Xu
, et al.
·
Journal of Pharmaceutical and Biomedical Analysis
·
8
Proguanil synergistically sensitizes ovarian cancer cells to olaparib by increasing DNA damage and inducing apoptosis
2022
·
Yan Wu
, Tianyu Wu
, et al.
·
International Journal of Medical Sciences
·
8
PDF
Synergistic augmentation of osimertinib‐induced autophagic death by proguanil or rapamycin in bladder cancer
2023
·
Di Xiao
, Simeng Xu
, et al.
·
MedComm
·
7
PDF
Phenformin synergistically sensitizes liver cancer cells to sorafenib by downregulating CRAF/ERK and PI3K/AKT/mTOR pathways.
2021
·
Lingli Huang
, Di Xiao
, et al.
·
PubMed
·
6
Synthesis, Anticancer Activities, and Mechanism of N-heptyl-containing Biguanide Derivatives
2022
·
Wei Wang
, Di Xiao
, et al.
·
Medicinal Chemistry
·
5
Synthesis, Anticancer Activity and Mechanism of Phenformin Derivatives
2022
·
Yufang Cao
, Simeng Xu
, et al.
·
ChemistrySelect
·
4
Fufang Gaoziban Pian alleviates anxiety and depression-like behavior in mice via the gut-brain axis: Involvement of the estrogen signaling pathway
2025
·
Wanting Ren
, Wenyue Yang
, et al.
·
Phytomedicine
·
1
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Works count:
17
Citation count:
408
H-index:
10
I10-index:
10
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