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William Markland

Observed names: Markland, William, W Markland, W. Markland
OpenAlex ID: A5028466818
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 · J.L Kim, K.A Morgenstern, et al. · Cell · 727
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Broad-Spectrum Antiviral Activity of the IMP Dehydrogenase Inhibitor VX-497: a Comparison with Ribavirin and Demonstration of Antiviral Additivity with Alpha Interferon
2000 · W. Markland, T. J. McQuaid, et al. · Antimicrobial Agents and Chemotherapy · 254
Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib)
2017 · Ursula A. Germann, Brinley F. Furey, et al. · Molecular Cancer Therapeutics · 233
Crystal structure of JNK3: a kinase implicated in neuronal apoptosis
1998 · Xiaoling Xie, Yong Gu, et al. · Structure · 198
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Directed evolution of a protein: selection of potent neutrophil elastase inhibitors displayed on M13 fusion phage.
1992 · B L Roberts, W Markland, et al. · Proceedings of the National Academy of Sciences · 198
M13 bacteriophage displaying disulfide-constrained microproteins
1993 · M.A. McLafferty, R.B. Kent, et al. · Gene · 175
Structure-Guided Design of Potent and Selective Pyrimidylpyrrole Inhibitors of Extracellular Signal-Regulated Kinase (ERK) Using Conformational Control
2009 · Alex M. Aronov, Qing Tang, et al. · Journal of Medicinal Chemistry · 144
LINGO-1, a Transmembrane Signaling Protein, Inhibits Oligodendrocyte Differentiation and Myelination through Intercellular Self-interactions
2012 · Scott Jepson, Bryan Vought, et al. · Journal of Biological Chemistry · 108
Iterative Optimization of High-Affinity Protease Inhibitors Using Phage Display. 1. Plasmin
1996 · William Markland, Arthur Charles Ley, et al. · Biochemistry · 93
Iterative Optimization of High-Affinity Protease Inhibitors Using Phage Display. 2. Plasma Kallikrein and Thrombin
1996 · William Markland, Arthur Charles Ley, et al. · Biochemistry · 92
Active-Site Residues of Escherichia coli DNA Gyrase Required in Coupling ATP Hydrolysis to DNA Supercoiling and Amino Acid Substitutions Leading to Novobiocin Resistance
2003 · Christian H. Gross, Jonathan D. Parsons, et al. · Antimicrobial Agents and Chemotherapy · 89
Design, construction and function of a multicopy display vector using fusions to the major coat protein of bacteriophage M13
1991 · W. Markland, B.L. Roberts, et al. · Gene · 72
Protease inhibitor display M13 phage: selection of high-affinity neutrophil elastase inhibitors
1992 · B.L. Roberts, W. Markland, et al. · Gene · 50
Signal-Dependent Translocation of Simian Virus 40 Large-T Antigen into Rat Liver Nuclei in a Cell-Free System
1987 · W Markland, A E Smith, et al. · Molecular and Cellular Biology · 49
Mutants of polyomavirus middle-T antigen
1987 · William Markland, Alan E. Smith · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 46
In vitro mutagenesis of the putative membrane-binding domain of polyomavirus middle-T antigen
1986 · W Markland, S H Cheng, et al. · Journal of Virology · 43
Mutations around the NG59 lesion indicate an active association of polyoma virus middle‐T antigen with pp60c‐src is required for cell transformation.
1986 · S.H. Cheng, W. Markland, et al. · The EMBO Journal · 40
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Site-directed mutagenesis of polyomavirus middle-T antigen sequences encoding tyrosine 315 and tyrosine 250
1986 · W Markland, B A Oostra, et al. · Journal of Virology · 34
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Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)
2008 · Luc J. Farmer, Guy Bemis, et al. · Bioorganic & Medicinal Chemistry Letters · 28
Purification and characterization of the NS3 serine protease domain of hepatitis C virus expressed in Saccharomyces cerevisiae.
1997 · W Markland, M Fitzgibbon, et al. · Journal of General Virology · 25
Abstract 4693: The selective ERK inhibitor BVD-523 is active in models of MAPK pathway-dependent cancers, including those with intrinsic and acquired drug resistance
2015 · Ursula Germann, Brinley Furey, et al. · Cancer Research · 21
Obtaining a family of high-affinity, high-specificity protein inhibitors of plasmin and plasma kallikrein
1996 · Arthur Charles Ley, William Markland, et al. · Molecular Diversity · 21
Structural and Kinetic Analyses of the Protease from an Amprenavir-Resistant Human Immunodeficiency Virus Type 1 Mutant Rendered Resistant to Saquinavir and Resensitized to Amprenavir
2000 · W. Markland, B. G. Rao, et al. · Journal of Virology · 20
Association of p62c-yes with polyomavirus middle T-antigen mutants correlates with transforming ability
1990 · S Kornbluth, S H Cheng, et al. · Journal of Virology · 20
Mapping of the amino-terminal half of polyomavirus middle-T antigen indicates that this region is the binding domain for pp60c-src
1987 · W Markland, A E Smith · Journal of Virology · 20
Works count: 56
Citation count: 2,857
H-index: 21
I10-index: 26
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