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Author

Ruju Chen

ORCID: 0000-0002-9574-7814
Observed ORCID: 0000-0002-9574-7814
OpenAlex ID: A5029320192
Epigenetic regulation of connective tissue growth factor by MicroRNA-214 delivery in exosomes from mouse or human hepatic stellate cells
2013 · Li Chen, Alyssa Charrier, et al. · Hepatology · 265
Adeno-Associated Virus-Mediated Gene Transfer to the Brain: Duration and Modulation of Expression
1999 · Warren D. Lo, Guang Qu, et al. · Human Gene Therapy · 188
Suppression of fibrogenic signaling in hepatic stellate cells by Twist1-dependent microRNA-214 expression: Role of exosomes in horizontal transfer of Twist1
2015 · Li Chen, Ruju Chen, et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 143
Exosomes mediate intercellular transfer of pro-fibrogenic connective tissue growth factor (CCN2) between hepatic stellate cells, the principal fibrotic cells in the liver
2014 · Alyssa Charrier, Ruju Chen, et al. · Surgery · 131
Generation of Neutralizing Activity against Human Immunodeficiency Virus Type 1 in Serum by Antibody Gene Transfer
2002 · Anne D. Lewis, Ruju Chen, et al. · Journal of Virology · 124
Therapeutic effects of serum extracellular vesicles in liver fibrosis
2018 · Li Chen, Ruju Chen, et al. · Journal of Extracellular Vesicles · 113
Connective tissue growth factor (CCN2) and microRNA-21 are components of a positive feedback loop in pancreatic stellate cells (PSC) during chronic pancreatitis and are exported in PSC-derived exosomes
2014 · Alyssa Charrier, Ruju Chen, et al. · Journal of Cell Communication and Signaling · 88
Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes # †
2009 · ZhenYue Tong, Ruju Chen, et al. · Hepatology · 78
Selective Rep-Cap Gene Amplification as a Mechanism for High-Titer Recombinant AAV Production from Stable Cell Lines
2000 · Xingluo Liu, Frosso Voulgaropoulou, et al. · Molecular Therapy · 78
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Pathways of production and delivery of hepatocyte exosomes
2017 · Li Chen, Ruju Chen, et al. · Journal of Cell Communication and Signaling · 77
Fibrogenic Signaling Is Suppressed in Hepatic Stellate Cells through Targeting of Connective Tissue Growth Factor (CCN2) by Cellular or Exosomal MicroRNA-199a-5p
2016 · Li Chen, Ruju Chen, et al. · American Journal Of Pathology · 74
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Extracellular Vesicles From Hepatocytes Are Therapeutic for Toxin-Mediated Fibrosis and Gene Expression in the Liver
2020 · Xinlei Li, Ruju Chen, et al. · Frontiers in Cell and Developmental Biology · 44
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Regulation of pancreatic inflammation by connective tissue growth factor ( CTGF / CCN 2)
2013 · Alyssa Charrier, Ruju Chen, et al. · Immunology · 29
Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes
2021 · Xinlei Li, Ruju Chen, et al. · Frontiers in Cell and Developmental Biology · 28
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Dynamic Changes in Function and Proteomic Composition of Extracellular Vesicles from Hepatic Stellate Cells during Cellular Activation
2020 · Xinlei Li, Ruju Chen, et al. · Cells · 28
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Gene Transfer into the CNS Using Recombinant Adeno-associated Virus: Analysis of Vector DNA Forms Resulting in Sustained Expression
1999 · K. Reed Clark, Thomas J. Sferra, et al. · Journal of drug targeting · 25
Effect of neutrophil depletion in acute cerebritis
1998 · Warren D Lo, Ruju Chen, et al. · Brain Research · 11
Production, Exacerbating Effect, and EV-Mediated Transcription of Hepatic CCN2 in NASH: Implications for Diagnosis and Therapy of NASH Fibrosis
2023 · Xinlei Li, Ruju Chen, et al. · International Journal of Molecular Sciences · 4
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Therapeutic Actions of Hepatocyte Extracellular Vesicles in a Murine Model of Diet-Induced Steatohepatitis with Fibrosis
2025 · Xinlei Li, Ruju Chen, et al. · Biomedicines · 1
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Proteomic changes in extracellular vesicles from hepatocytes after cytotoxic ethanol injury
2020 · Xinlei Li, Ruju Chen, et al. · The FASEB Journal
Comparative Analysis of Proteins in Extracellular Vesicles from Quiescent versus Activated Hepatic Stellate Cells
2019 · Ruju Chen, Xinlei Li, et al. · The FASEB Journal
Works count: 22
Citation count: 1,529
H-index: 16
I10-index: 17
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