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Hilmar Bischoff

The mechanism of alpha-glucosidase inhibition in the management of diabetes.
1995 · H Bischoff · PubMed · 231
Crystal structures of human pancreatic α-amylase in complex with carbohydrate and proteinaceous inhibitors
2000 · Virginie NAHOUM, Geneviève ROUX, et al. · Biochemical Journal · 190
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Cerivastatin: pharmacology of a novel synthetic and highly active HMG-CoA reductase inhibitor
1997 · Hilmar Bischoff, Rolf Angerbauer, et al. · Atherosclerosis · 109
The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor
1997 · Spyros E Zographos, Nikos G Oikonomakos, et al. · Structure · 79
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Enzyme-Catalyzed Condensation Reaction in a Mammalian α-Amylase. High-Resolution Structural Analysis of an Enzyme−Inhibitor Complex
2001 · Minxie Qian, Virginie Nahoum, et al. · Biochemistry · 76
Repetitive postprandial hyperglycemia increases cardiac ischemia/reperfusion injury: prevention by the α‐glucosidase inhibitor acarbose
2005 · Stefan Frantz, Laura Calvillo, et al. · The FASEB Journal · 70
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40th EASD Annual Meeting of the European Association for the Study of Diabetes
2004 · M. Veitenhansl, K. Stegner, et al. · Diabetologia · 70
Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3‐isopropyl 4‐(2‐chlorophenyl)‐1,4‐dihydro‐1‐ethyl‐2‐methyl‐pyridine‐3,5,6‐tricarboxylate
1999 · Nikos G. Oikonomakos, Katerina E. Tsitsanou, et al. · Protein Science · 45
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Preclinical and clinical pharmacology of cerivastatin
1998 · Hilmar Bischoff, Allen H Heller · The American Journal of Cardiology · 42
Cholesteryl ester transfer protein and its inhibition
2010 · Olaf Weber, Hilmar Bischoff, et al. · Cellular and Molecular Life Sciences · 37
Minor structural modifications convert a selective PPARα agonist into a potent, highly selective PPARδ agonist
2005 · Stefan Weigand, Hilmar Bischoff, et al. · Bioorganic & Medicinal Chemistry Letters · 29
BAY W 6228
1994 · R. Angerbauer, H. Bischoff, et al. · Drugs of the Future · 28
Novel tetrahydrochinoline derived CETP inhibitors
2010 · Carsten Schmeck, Heike Gielen-Haertwig, et al. · Bioorganic & Medicinal Chemistry Letters · 24
Increased platelet activation in young Zucker rats with impaired glucose tolerance is improved by acarbose
2004 · Martin Eigenthaler, Hilmar Bischoff, et al. · Thrombosis and Haemostasis · 24
Inhibition of glycogenolysis enhances gluconeogenic precursor uptake by the liver of conscious dogs
1997 · Masakazu Shiota, Patricia A. Jackson, et al. · American Journal of Physiology-Endocrinology and Metabolism · 24
Acarbose ‐ ein neues Wirkprinzip in der Diabetestherapie
1994 · Hilmar Bischoff, Hans Jürgen Ahr, et al. · Nachrichten aus Chemie Technik und Laboratorium · 23
Identification and optimization of tetrahydro-2H-3-benzazepin-2-ones as squalene synthase inhibitors
2011 · Nils Griebenow, Timo Flessner, et al. · Bioorganic & Medicinal Chemistry Letters · 20
Chromanol derivatives—A novel class of CETP inhibitors
2010 · Alexandros Vakalopoulos, Carsten Schmeck, et al. · Bioorganic & Medicinal Chemistry Letters · 20
Cerivastatin (BAY w 6228): A Novel HMG‐CoA Reductase Inhibitor
1998 · J. Kuhlmann, W. Mück, et al. · Cardiovascular Drug Reviews · 19
Preclinical review of cerivastatin sodium—a step forward in HMG-CoA reductase inhibition
1998 · H. Bischoff, R. Angerbauer, et al. · Atherosclerosis · 19
93 Cerivastatin: High enzyme affinity and active metabolites contribute to its high pharmacological activity
1997 · H. Bischoff, R. Angerbauer, et al. · Atherosclerosis · 17
Early acarbose treatment ameliorates resistance of insulin-regulated GLUT4 trafficking in obese Zucker rats
2002 · Daniela Ledwig, Heidi Müller, et al. · European Journal of Pharmacology · 15
Prediction of a potentially effective dose in humans for BAY 60–5521, a potent inhibitor of cholesteryl ester transfer protein (CETP) by allometric species scaling and combined pharmacodynamic and physiologically‐based pharmacokinetic modelling
2011 · Olaf Weber, Stefan Willmann, et al. · British Journal of Clinical Pharmacology · 13
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Identification of 4H,6H-[2]benzoxepino[4,5-c][1,2]oxazoles as novel squalene synthase inhibitors
2011 · Nils Griebenow, Anja Buchmueller, et al. · Bioorganic & Medicinal Chemistry Letters · 11
Fluorine-Substitution in Cholesteryl Ester Transfer Protein Inhibitors (CETPInhibitors) – Biology, Chemistry, SAR, and Properties
2004 · Holger Paulsena, Siegfried Zaiss, et al. · CHIMIA International Journal for Chemistry · 9
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Works count: 41
Citation count: 1,282
H-index: 19
I10-index: 24
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