Author

Andrew D. Napper

Observed names: A D Napper, A Napper, A. D. Napper, Andrew D Napper, Andrew Napper, Napper, A.D.

Institution: Bristol-Myers Squibb (United States)

Observed institutions: Pennsylvania State University, Bucknell University, Alfred I. duPont Hospital for Children, Harvard University, Thomas Jefferson University, Lankenau Institute for Medical Research, Bristol-Myers Squibb (United States), Constellation Pharmaceuticals (United States), University of Pennsylvania, University of Delaware

ORCID: 0009-0002-6923-0704

Observed ORCID: 0009-0002-6923-0704

OpenAlex ID: A5031030579

Substrate-specific Activation of Sirtuins by Resveratrol

2005 · Matt Kaeberlein, Thomas McDonagh, et al. · Journal of Biological Chemistry · 745

Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1

2005 · Andrew D. Napper, Jeffrey Hixon, et al. · Journal of Medicinal Chemistry · 523

Identification of Specific Inhibitors of Human RAD51 Recombinase Using High-Throughput Screening

2011 · Fei Huang, Nuzhat A. Motlekar, et al. · ACS Chemical Biology · 231

A Stereospecific Cyclization Catalyzed by an Antibody

1987 · Andrew D. Napper, Stephen J. Benkovic, et al. · Science · 129

Mitoxantrone Targets Human Ubiquitin-Specific Peptidase 11 (USP11) and Is a Potent Inhibitor of Pancreatic Cancer Cell Survival

2013 · Richard A. Burkhart, Yu Peng, et al. · Molecular Cancer Research · 117

Purification and characterization of multiple forms of the pineapple-stem-derived cysteine proteinases ananain and comosain

1994 · A D Napper, S P Bennett, et al. · Biochemical Journal · 111

Assay Guidance Manual

2004 · G. Sitta Sittampalam, Nathan P. Coussens, et al. · 110

Identification of Novel Inhibitors of Dietary Lipid Absorption Using Zebrafish

2010 · Justin D. Clifton, Edinson Lucumi, et al. · PLoS ONE · 88

PDF

Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-d-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC)

2009 · Sharmila Sivendran, Victoria Jones, et al. · Bioorganic & Medicinal Chemistry · 79

Catalysis of a stereospecific bimolecular amide synthesis by an antibody.

1988 · S J Benkovic, A D Napper, et al. · Proceedings of the National Academy of Sciences · 78

Drug Discovery for Duchenne Muscular Dystrophy via Utrophin Promoter Activation Screening

2011 · Catherine Moorwood, Olga Lozynska, et al. · PLoS ONE · 69

PDF

Antibody-Catalyzed Hydrolysis of an Unsubstituted Amide

1994 · Mark T. Martin, Thelma S. Angeles, et al. · Journal of the American Chemical Society · 69

Novel high-throughput screen against Candida albicans identifies antifungal potentiators and agents effective against biofilms

2011 · M. D. LaFleur, E. Lucumi, et al. · Journal of Antimicrobial Chemotherapy · 59

Potentiometric biosensor employing catalytic antibodies as the molecular recognition element

1990 · Gary F. Blackburn, David B. Talley, et al. · Analytical Chemistry · 52

Assay Guidance Manual : Quantitative Biology and Pharmacology in Preclinical Drug Discovery

2018 · Nathan P. Coussens, G. Sitta Sittampalam, et al. · Clinical and Translational Science · 50

PDF

Beta-hairpin hydrogels as scaffolds for high-throughput drug discovery in three-dimensional cell culture

2017 · Peter Worthington, Katherine M. Drake, et al. · Analytical Biochemistry · 49

Discovery of Potent Small-Molecule Inhibitors of Multidrug-Resistant Plasmodium falciparum Using a Novel Miniaturized High-Throughput Luciferase-Based Assay

2010 · Edinson Lucumi, Claire Darling, et al. · Antimicrobial Agents and Chemotherapy · 47

Kinetic Characterization and Molecular Docking of a Novel, Potent, and Selective Slow-Binding Inhibitor of Human Cathepsin L

2008 · Parag P. Shah, Michael C. Myers, et al. · Molecular Pharmacology · 44

A Sensitive Luminescent Assay for the Histone Methyltransferase NSD1 and Other SAM-Dependent Enzymes

2014 · Katherine M. Drake, Venita G. Watson, et al. · Assay and Drug Development Technologies · 35

Mechanistic studies of a tyrosine-dependent catalytic antibody

1991 · Mark T. Martin, Andrew D. Napper, et al. · Biochemistry · 35

Evaluation of an Orthogonal Pooling Strategy for Rapid High-Throughput Screening of Proteases

2008 · Nuzhat Motlekar, Scott L. Diamond, et al. · Assay and Drug Development Technologies · 29

Implementation of a High-Throughput Pilot Screen in Peptide Hydrogel-Based Three-Dimensional Cell Cultures

2019 · Peter Worthington, Katherine M. Drake, et al. · SLAS DISCOVERY · 28

Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin

2005 · Thomas McDonagh, Jeffrey Hixon, et al. · Methods · 27

Disruption of Annexin II /p11 Interaction Suppresses Leukemia Cell Binding, Homing and Engraftment, and Sensitizes the Leukemia Cells to Chemotherapy

2015 · Anilkumar Gopalakrishnapillai, E. Anders Kolb, et al. · PLoS ONE · 25

PDF

Identification and characterization of 3-substituted pyrazolyl esters as alternate substrates for cathepsin B: The confounding effects of DTT and cysteine in biological assays

2007 · Michael C. Myers, Andrew D. Napper, et al. · Bioorganic & Medicinal Chemistry Letters · 23

Works count: 94

Citation count: 3,033

H-index: 24

I10-index: 31