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Author

Lars V. Bock

Observed names: Bock, L., Bock, Lars, Bock, Lars V., L.V. Bock, Lars Bock, Lars V Bock
ORCID: 0000-0003-4554-7336
Observed ORCID: 0000-0003-4554-7336
OpenAlex ID: A5031556547
Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM
2015 · Niels Fischer, Piotr Neumann, et al. · Nature · 368
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Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P
2017 · Paul Huter, Stefan Arenz, et al. · Molecular Cell · 188
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Energy barriers and driving forces in tRNA translocation through the ribosome
2013 · Lars V Bock, Christian Blau, et al. · Nature Structural & Molecular Biology · 184
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A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest
2016 · Stefan Arenz, Lars V. Bock, et al. · Nature Communications · 119
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The pathway to GTPase activation of elongation factor SelB on the ribosome
2016 · Niels Fischer, Piotr Neumann, et al. · Nature · 116
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics
2021 · Bertrand Beckert, Elodie C. Leroy, et al. · Nature Communications · 100
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Structural conservation of antibiotic interaction with ribosomes
2023 · Helge Paternoga, Caillan Crowe-McAuliffe, et al. · Nature Structural & Molecular Biology · 96
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Automated cryo-EM structure refinement using correlation-driven molecular dynamics
2019 · Maxim Igaev, Carsten Kutzner, et al. · eLife · 91
Effects of cryo-EM cooling on structural ensembles
2022 · Lars V. Bock, Helmut Grubmüller · Nature Communications · 79
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Active role of elongation factor G in maintaining the mRNA reading frame during translation
2019 · Bee-Zen Peng, Lars V. Bock, et al. · Science Advances · 47
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Thermodynamic control of −1 programmed ribosomal frameshifting
2019 · Lars V. Bock, Neva Caliskan, et al. · Nature Communications · 41
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Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation
2015 · Lars V. Bock, Christian Blau, et al. · Nucleic Acids Research · 40
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Molecular simulations of the ribosome and associated translation factors
2017 · Lars V Bock, Michal H Kolář, et al. · Current Opinion in Structural Biology · 39
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The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome
2024 · Felix Gersteuer, Martino Morici, et al. · Nature Communications · 38
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Simulation of Complex Biomolecular Systems: The Ribosome Challenge
2023 · Lars V. Bock, Sara Gabrielli, et al. · Annual Review of Biophysics · 34
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Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88
2024 · Simon M. Lauer, Maren Reepmeyer, et al. · Nature Communications · 28
Chemomechanical Regulation of SNARE Proteins Studied with Molecular Dynamics Simulations
2010 · Lars V. Bock, Brian Hutchings, et al. · Biophysical Journal · 23
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tRNA Dissociation from EF-Tu after GTP Hydrolysis: Primary Steps and Antibiotic Inhibition
2019 · Malte Warias, Helmut Grubmüller, et al. · Biophysical Journal · 22
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Single-particle Cryo-EM and molecular dynamics simulations: A perfect match
2024 · Lars V. Bock, Maxim Igaev, et al. · Current Opinion in Structural Biology · 14
Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel
2022 · Michal H Kolář, Gabor Nagy, et al. · Nucleic Acids Research · 14
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Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1
2025 · Barbara Orth, Pavel Pohl, et al. · Nature Communications · 13
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RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity
2024 · Martino Morici, Sara Gabrielli, et al. · Nature Communications · 12
Effects of cryo-EM cooling on structural ensembles
2022 · Lars V. Bock, Helmut Grubmuller · Biophysical Journal · 8
Transient non-local interactions dominate the dynamics of measles virus NTAIL
2025 · Lillian Otteson, Gabor Nagy, et al. · Communications Chemistry · 4
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Chemomechanical Regulation of Snare Proteins Studied with Molecular Dynamics Simulations
2010 · Lars Bock, Brian Hutchings, et al. · Biophysical Journal · 2
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Works count: 111
Citation count: 1,731
H-index: 18
I10-index: 22
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