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Ana Paula Arruda

Observed names: A.P. Arruda, ANA PAULA ARRUDA, AP Arruda, Ana P. Arruda, Ana Paula ARRUDA, Ana Paula Arruda, Arruda, Ana Paula
Observed institutions: Broad Institute, Universidade Federal do Rio de Janeiro, Harvard University, Universidade Estadual de Campinas (UNICAMP), Chan Zuckerberg Biohub San Francisco, Massachusetts Institute of Technology, University of California, Berkeley
ORCID: 0000-0001-6179-2687
Observed ORCID: 0000-0001-6179-2687
OpenAlex ID: A5031995461
Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity
2014 · Ana Paula Arruda, Benedicte M Pers, et al. · Nature Medicine · 722
Calcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes
2015 · Ana Paula Arruda, Gökhan S. Hotamisligil · Cell Metabolism · 343
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NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis
2017 · Scott B. Widenmaier, Nicole A. Snyder, et al. · Cell · 232
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Inhibition of Hypothalamic Inflammation Reverses Diet-Induced Insulin Resistance in the Liver
2012 · Marciane Milanski, Ana P. Arruda, et al. · Diabetes · 225
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Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 · Alexander Bartelt, Scott B Widenmaier, et al. · Nature Medicine · 208
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Low-Grade Hypothalamic Inflammation Leads to Defective Thermogenesis, Insulin Resistance, and Impaired Insulin Secretion
2011 · Ana Paula Arruda, Marciane Milanski, et al. · Endocrinology · 203
Deletion of Tumor Necrosis Factor-α Receptor 1 (TNFR1) Protects against Diet-induced Obesity by Means of Increased Thermogenesis
2009 · Talita Romanatto, Erika A. Roman, et al. · Journal of Biological Chemistry · 156
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Regulation of liver subcellular architecture controls metabolic homeostasis
2022 · Güneş Parlakgül, Ana Paula Arruda, et al. · Nature · 136
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Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism
2020 · Amir Tirosh, Gurol Tuncman, et al. · Cell Metabolism · 104
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Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity
2015 · Suneng Fu, Abdullah Yalcin, et al. · Science Translational Medicine · 97
Hypothalamic Actions of Tumor Necrosis Factor α Provide the Thermogenic Core for the Wastage Syndrome in Cachexia
2009 · Ana Paula Arruda, Marciane Milanski, et al. · Endocrinology · 95
Defective Regulation of the Ubiquitin/Proteasome System in the Hypothalamus of Obese Male Mice
2014 · Leticia M. Ignacio-Souza, Bruna Bombassaro, et al. · Endocrinology · 81
Role of Sarco/Endoplasmic Reticulum Ca2+-ATPase in Thermogenesis
2005 · Leopoldo de Meis, Ana Paula Arruda, et al. · Bioscience Reports · 80
TNF-α transiently induces endoplasmic reticulum stress and an incomplete unfolded protein response in the hypothalamus
2010 · R.G. Denis, A.P. Arruda, et al. · Neuroscience · 65
Cold Tolerance in Hypothyroid Rabbits: Role of Skeletal Muscle Mitochondria and Sarcoplasmic Reticulum Ca2+ ATPase Isoform 1 Heat Production
2008 · Ana Paula Arruda, Luisa A. Ketzer, et al. · Endocrinology · 55
Defective STIM-mediated store operated Ca2+ entry in hepatocytes leads to metabolic dysfunction in obesity
2017 · Ana Paula Arruda, Benedicte Mengel Pers, et al. · eLife · 54
Taurine enhances the anorexigenic effects of insulin in the hypothalamus of rats
2011 · Carina S. Solon, Daniel Franci, et al. · Amino Acids · 49
Integration of ER protein quality control mechanisms defines β cell function and ER architecture
2022 · Neha Shrestha, Mauricio Torres, et al. · Journal of Clinical Investigation · 48
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Hyperthyroidism increases the uncoupled ATPase activity and heat production by the sarcoplasmic reticulum Ca2+-ATPase
2003 · Ana Paula ARRUDA, Wagner S. da-SILVA, et al. · Biochemical Journal · 48
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Spatial mapping of hepatic ER and mitochondria architecture reveals zonated remodeling in fasting and obesity
2024 · Güneş Parlakgül, Song Pang, et al. · Nature Communications · 46
Identification of a Ca2+-ATPase in Brown Adipose Tissue Mitochondria
2006 · Leopoldo de Meis, Ana Paula Arruda, et al. · Journal of Biological Chemistry · 46
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Thermogenic activity of Ca2+-ATPase from skeletal muscle heavy sarcoplasmic reticulum: The role of ryanodine Ca2+ channel
2007 · Ana Paula Arruda, Mariana Nigro, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 43
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Chaperone Insufficiency Links TLR4 Protein Signaling to Endoplasmic Reticulum Stress
2012 · Andressa Coope, Marciane Milanski, et al. · Journal of Biological Chemistry · 40
CoQ imbalance drives reverse electron transport to disrupt liver metabolism
2025 · Renata L. S. Goncalves, Zeqiu Branden Wang, et al. · Nature · 35
The impact of science in Brazil
2007 · Leopoldo de Meis, Ana Paula Arruda, et al. · IUBMB Life · 34
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Works count: 56
Citation count: 3,543
H-index: 27
I10-index: 39
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