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Emma J Searle
Observed names:
Dr. Emma Searle,
E. Searle,
E.J. Searle,
Emma J. Searle,
Emma Searle,
Searle, Emma
show all 6
Institution:
The Christie NHS Foundation Trust
Observed institutions:
Manchester Academic Health Science Centre,
University of Manchester,
The Christie Hospital,
The Christie NHS Foundation Trust,
Royal Manchester Children's Hospital,
Cancer Research UK Manchester Centre
show all 6
ORCID:
0000-0002-3942-3081
Observed ORCID:
0000-0002-3942-3081
OpenAlex ID:
A5032366727
Elranatamab in relapsed or refractory multiple myeloma: phase 2 MagnetisMM-3 trial results
2023
·
Alexander M. Lesokhin
, Michael H. Tomasson
, et al.
·
Nature Medicine
·
652
PDF
Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
2023
·
Luciano Nicosia
, Gary J. Spencer
, et al.
·
Cancer Cell
·
122
Teclistamab in Combination with Subcutaneous Daratumumab and Lenalidomide in Patients with Multiple Myeloma: Results from One Cohort of MajesTEC-2, a Phase1b, Multicohort Study
2022
·
Emma Searle
, Hang Quach
, et al.
·
Blood
·
61
Targeting hypoxia in solid and haematological malignancies
2022
·
Bill Harris
, Sana Saleem
, et al.
·
Journal of Experimental & Clinical Cancer Research
·
53
PDF
A First-in-Human Phase 1 Study of the Menin-KMT2A (MLL1) Inhibitor JNJ-75276617 in Adult Patients with Relapsed/Refractory Acute Leukemia Harboring KMT2A or NPM1 Alterations
2023
·
Elias Jabbour
, Emma Searle
, et al.
·
Blood
·
51
Talquetamab + Pomalidomide in Patients with Relapsed/Refractory Multiple Myeloma: Safety and Preliminary Efficacy Results from the Phase 1b MonumenTAL-2 Study
2023
·
Jeffrey Matous
, Noa Biran
, et al.
·
Blood
·
45
Bleximenib Dose Optimization and Determination of RP2D from a Phase 1 Study in Relapsed/Refractory Acute Leukemia Patients with KMT2A and NPM1 Alterations
2024
·
Emma Searle
, Christian Recher
, et al.
·
Blood
·
40
The Dynamic Interface Between the Bone Marrow Vascular Niche and Hematopoietic Stem Cells in Myeloid Malignancy
2021
·
Laura Mosteo
, Joanna Storer
, et al.
·
Frontiers in Cell and Developmental Biology
·
36
PDF
Initial Findings from a First-in-Human Phase 1a/b Trial of NX-5948, a Selective Bruton's Tyrosine Kinase (BTK) Degrader, in Patients with Relapsed/Refractory B Cell Malignancies
2023
·
Emma Searle
, Francesco Forconi
, et al.
·
Blood
·
34
Efficacy and Safety of the Bruton's Tyrosine Kinase (BTK) Degrader NX-5948 in Patients with Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia (CLL): Updated Results from an Ongoing Phase 1a/b Study
2024
·
Nirav N. Shah
, Zulfa Omer
, et al.
·
Blood
·
33
Teclistamab, Daratumumab, and Pomalidomide in Patients with Relapsed/Refractory Multiple Myeloma: Results from the Majestec-2 Cohort a and Trimm-2 Studies
2024
·
Anita D'Souza
, Luciano J. Costa
, et al.
·
Blood
·
28
Phase 1b Study of Menin-KMT2A Inhibitor Bleximenib in Combination with Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia with KMT2Ar or NPM1 Alterations
2024
·
Christian Recher
, Jenny O'Nions
, et al.
·
Blood
·
27
PDF
Recombinant factor VIIa and other pro-haemostatic therapies in primary postpartum haemorrhage
2008
·
E. Searle
, S. Pavord
, et al.
·
Best Practice & Research Clinical Obstetrics & Gynaecology
·
15
Bleximenib in combination with intensive chemotherapy: A phase 1b study in newly diagnosed Acute Myeloid Leukemia with KMT2A or NPM1 alterations
2025
·
Hartmut Döhner
, Andre Schuh
, et al.
·
Blood
·
14
PDF
P30 Single Cohort Results From Majestec-2: Teclistamab (tec) in Combination With Subcutaneous Daratumumab (dara) and Lenalidomide (len) in Patients With Multiple Myeloma (mm)
2023
·
E. Searle
, H. Quach
, et al.
·
HemaSphere
·
14
Akt inhibition improves long‐term tumour control following radiotherapy by altering the microenvironment
2017
·
Emma J Searle
, Brian A Telfer
, et al.
·
EMBO Molecular Medicine
·
14
PDF
Emerging Opportunities for the Combination of Molecularly Targeted Drugs with Radiotherapy
2014
·
E.J. Searle
, T.M. Illidge
, et al.
·
Clinical Oncology
·
14
Inflammatory BCG adenitis associated with immune reconstitution following allogeneic haematopoietic stem cell transplant in infancy
2009
·
E. Searle
, H. Patel
, et al.
·
Pediatric Blood & Cancer
·
13
Mezigdomide (MEZI) in Novel-Novel Combinations for Relapsed or Refractory Multiple Myeloma (RRMM): Preliminary Results from the CA057-003 Trial
2024
·
Luciano J. Costa
, Fredrik Schjesvold
, et al.
·
Blood
·
12
Patient Experiences of Using Wearable Health Monitors During Cancer Treatment: A Qualitative Study
2024
·
S. Collinson
, S. Ingram-Walpole
, et al.
·
Clinical Oncology
·
10
S196: Elranatamab, a B-cell Maturation Antigen (bcma)-cd3 Bispecific Antibody, for Patients With Relapsed/refractory Multiple Myeloma: Extended Follow up and Biweekly Administration From Magnetismm-3
2023
·
Mohamad Mohty
, Michael H. Tomasson
, et al.
·
HemaSphere
·
7
P865: Teclistamab in Combination With Lenalidomide in Previously Treated Patients With Multiple Myeloma in the Phase 1b Multicohort Majestec-2 Study
2023
·
Carlyn Tan
, Emma Searle
, et al.
·
HemaSphere
·
7
Long-term efficacy and safety of etentamig, a B-cell maturation antigen (BCMA) bispecific antibody in patients with relapsed/refractory multiple myeloma (RRMM).
2025
·
Muhamed Baljevic
, Peter M. Voorhees
, et al.
·
Journal of Clinical Oncology
·
6
Potent Pre-Clinical and Early Phase Clinical Activity of EP300/CBP Bromodomain Inhibitor CCS1477 in Multiple Myeloma
2022
·
Luciano Nicosia
, Nigel Brooks
, et al.
·
Blood
·
6
Phase 1b study of bleximenib in combination with venetoclax in Acute Myeloid Leukemia with KMT2A or NPM1 alterations
2025
·
Jenny O'Nions
, Andrew Wei
, et al.
·
Blood
·
5
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Works count:
83
Citation count:
1,360
H-index:
14
I10-index:
19
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